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GPR149 (G protein-coupled receptor 149)

Identity

Alias_symbol (synonym)PGR10
IEDA
Other alias
HGNC (Hugo) GPR149
LocusID (NCBI) 344758
Atlas_Id 63965
Location 3q25.2  [Link to chromosome band 3q25]
Location_base_pair Starts at 154337672 and ends at 154429715 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPR149   23627
Cards
Entrez_Gene (NCBI)GPR149  344758  G protein-coupled receptor 149
AliasesIEDA; PGR10
GeneCards (Weizmann)GPR149
Ensembl hg19 (Hinxton)ENSG00000174948 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174948 [Gene_View]  chr3:154337672-154429715 [Contig_View]  GPR149 [Vega]
ICGC DataPortalENSG00000174948
TCGA cBioPortalGPR149
AceView (NCBI)GPR149
Genatlas (Paris)GPR149
WikiGenes344758
SOURCE (Princeton)GPR149
Genetics Home Reference (NIH)GPR149
Genomic and cartography
GoldenPath hg38 (UCSC)GPR149  -     chr3:154337672-154429715 -  3q25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR149  -     3q25.2   [Description]    (hg19-Feb_2009)
EnsemblGPR149 - 3q25.2 [CytoView hg19]  GPR149 - 3q25.2 [CytoView hg38]
Mapping of homologs : NCBIGPR149 [Mapview hg19]  GPR149 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AY255534 BC156849 DQ318360
RefSeq transcript (Entrez)NM_001038705
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPR149
Cluster EST : UnigeneHs.688231 [ NCBI ]
CGAP (NCI)Hs.688231
Alternative Splicing GalleryENSG00000174948
Gene ExpressionGPR149 [ NCBI-GEO ]   GPR149 [ EBI - ARRAY_EXPRESS ]   GPR149 [ SEEK ]   GPR149 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR149 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)344758
GTEX Portal (Tissue expression)GPR149
Human Protein AtlasENSG00000174948-GPR149 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86SP6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86SP6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86SP6
Splice isoforms : SwissVarQ86SP6
PhosPhoSitePlusQ86SP6
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)GPR149
DMDM Disease mutations344758
Blocks (Seattle)GPR149
SuperfamilyQ86SP6
Human Protein Atlas [tissue]ENSG00000174948-GPR149 [tissue]
Peptide AtlasQ86SP6
IPIIPI00328434   
Protein Interaction databases
DIP (DOE-UCLA)Q86SP6
IntAct (EBI)Q86SP6
FunCoupENSG00000174948
BioGRIDGPR149
STRING (EMBL)GPR149
ZODIACGPR149
Ontologies - Pathways
QuickGOQ86SP6
Ontology : AmiGOpreantral ovarian follicle growth  antral ovarian follicle growth  G-protein coupled receptor activity  integral component of plasma membrane  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  neuropeptide signaling pathway  chemical synaptic transmission  neuropeptide binding  neuron projection  negative regulation of ovulation  
Ontology : EGO-EBIpreantral ovarian follicle growth  antral ovarian follicle growth  G-protein coupled receptor activity  integral component of plasma membrane  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  neuropeptide signaling pathway  chemical synaptic transmission  neuropeptide binding  neuron projection  negative regulation of ovulation  
NDEx NetworkGPR149
Atlas of Cancer Signalling NetworkGPR149
Wikipedia pathwaysGPR149
Orthology - Evolution
OrthoDB344758
GeneTree (enSembl)ENSG00000174948
Phylogenetic Trees/Animal Genes : TreeFamGPR149
HOVERGENQ86SP6
HOGENOMQ86SP6
Homologs : HomoloGeneGPR149
Homology/Alignments : Family Browser (UCSC)GPR149
Gene fusions - Rearrangements
Fusion: Tumor Portal GPR149
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR149 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR149
dbVarGPR149
ClinVarGPR149
1000_GenomesGPR149 
Exome Variant ServerGPR149
ExAC (Exome Aggregation Consortium)ENSG00000174948
GNOMAD BrowserENSG00000174948
Genetic variants : HAPMAP344758
Genomic Variants (DGV)GPR149 [DGVbeta]
DECIPHERGPR149 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR149 
Mutations
ICGC Data PortalGPR149 
TCGA Data PortalGPR149 
Broad Tumor PortalGPR149
OASIS PortalGPR149 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR149  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPR149
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPR149
DgiDB (Drug Gene Interaction Database)GPR149
DoCM (Curated mutations)GPR149 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPR149 (select a term)
intoGenGPR149
Cancer3DGPR149(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenGPR149
Genetic Testing Registry GPR149
NextProtQ86SP6 [Medical]
TSGene344758
GENETestsGPR149
Target ValidationGPR149
Huge Navigator GPR149 [HugePedia]
snp3D : Map Gene to Disease344758
BioCentury BCIQGPR149
ClinGenGPR149
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD344758
Chemical/Pharm GKB GenePA134981369
Clinical trialGPR149
Miscellaneous
canSAR (ICR)GPR149 (select the gene name)
Probes
Litterature
PubMed2 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPR149
EVEXGPR149
GoPubMedGPR149
iHOPGPR149
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 11:49:31 CET 2017

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