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GPR161 (G protein-coupled receptor 161)

Identity

Alias_symbol (synonym)RE2
Other alias
HGNC (Hugo) GPR161
LocusID (NCBI) 23432
Atlas_Id 53926
Location 1q24.2  [Link to chromosome band 1q24]
Location_base_pair Starts at 168079542 and ends at 168137667 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CD247 (1q24.2) / GPR161 (1q24.2)GPR161 (1q24.2) / ZNF462 (9q31.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Adenocarcinoma


External links

Nomenclature
HGNC (Hugo)GPR161   23694
Cards
Entrez_Gene (NCBI)GPR161  23432  G protein-coupled receptor 161
AliasesRE2
GeneCards (Weizmann)GPR161
Ensembl hg19 (Hinxton)ENSG00000143147 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143147 [Gene_View]  chr1:168079542-168137667 [Contig_View]  GPR161 [Vega]
ICGC DataPortalENSG00000143147
TCGA cBioPortalGPR161
AceView (NCBI)GPR161
Genatlas (Paris)GPR161
WikiGenes23432
SOURCE (Princeton)GPR161
Genetics Home Reference (NIH)GPR161
Genomic and cartography
GoldenPath hg38 (UCSC)GPR161  -     chr1:168079542-168137667 -  1q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR161  -     1q24.2   [Description]    (hg19-Feb_2009)
EnsemblGPR161 - 1q24.2 [CytoView hg19]  GPR161 - 1q24.2 [CytoView hg38]
Mapping of homologs : NCBIGPR161 [Mapview hg19]  GPR161 [Mapview hg38]
OMIM612250   
Gene and transcription
Genbank (Entrez)AA662800 AF091890 AK026059 AK056040 AK091271
RefSeq transcript (Entrez)NM_001267609 NM_001267610 NM_001267611 NM_001267612 NM_001267613 NM_001267614 NM_001349632 NM_001349633 NM_001349634 NM_001349635 NM_007369 NM_153832
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPR161
Cluster EST : UnigeneHs.271809 [ NCBI ]
CGAP (NCI)Hs.271809
Alternative Splicing GalleryENSG00000143147
Gene ExpressionGPR161 [ NCBI-GEO ]   GPR161 [ EBI - ARRAY_EXPRESS ]   GPR161 [ SEEK ]   GPR161 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR161 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23432
GTEX Portal (Tissue expression)GPR161
Human Protein AtlasENSG00000143147-GPR161 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N6U8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N6U8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N6U8
Splice isoforms : SwissVarQ8N6U8
PhosPhoSitePlusQ8N6U8
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)GPR161
DMDM Disease mutations23432
Blocks (Seattle)GPR161
SuperfamilyQ8N6U8
Human Protein Atlas [tissue]ENSG00000143147-GPR161 [tissue]
Peptide AtlasQ8N6U8
HPRD17070
IPIIPI01014708   IPI00414738   IPI00642772   IPI00171156   IPI00985154   IPI00383926   
Protein Interaction databases
DIP (DOE-UCLA)Q8N6U8
IntAct (EBI)Q8N6U8
FunCoupENSG00000143147
BioGRIDGPR161
STRING (EMBL)GPR161
ZODIACGPR161
Ontologies - Pathways
QuickGOQ8N6U8
Ontology : AmiGOG-protein coupled receptor activity  cilium  G-protein coupled receptor signaling pathway  multicellular organism development  integral component of membrane  endocytic vesicle membrane  positive regulation of cAMP biosynthetic process  recycling endosome  ciliary membrane  negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning  
Ontology : EGO-EBIG-protein coupled receptor activity  cilium  G-protein coupled receptor signaling pathway  multicellular organism development  integral component of membrane  endocytic vesicle membrane  positive regulation of cAMP biosynthetic process  recycling endosome  ciliary membrane  negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning  
NDEx NetworkGPR161
Atlas of Cancer Signalling NetworkGPR161
Wikipedia pathwaysGPR161
Orthology - Evolution
OrthoDB23432
GeneTree (enSembl)ENSG00000143147
Phylogenetic Trees/Animal Genes : TreeFamGPR161
HOVERGENQ8N6U8
HOGENOMQ8N6U8
Homologs : HomoloGeneGPR161
Homology/Alignments : Family Browser (UCSC)GPR161
Gene fusions - Rearrangements
Fusion : MitelmanCD247/GPR161 [1q24.2/1q24.2]  [t(1;1)(q24;q24)]  
Fusion: Tumor Portal GPR161
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR161 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR161
dbVarGPR161
ClinVarGPR161
1000_GenomesGPR161 
Exome Variant ServerGPR161
ExAC (Exome Aggregation Consortium)ENSG00000143147
GNOMAD BrowserENSG00000143147
Genetic variants : HAPMAP23432
Genomic Variants (DGV)GPR161 [DGVbeta]
DECIPHERGPR161 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR161 
Mutations
ICGC Data PortalGPR161 
TCGA Data PortalGPR161 
Broad Tumor PortalGPR161
OASIS PortalGPR161 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR161  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPR161
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPR161
DgiDB (Drug Gene Interaction Database)GPR161
DoCM (Curated mutations)GPR161 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPR161 (select a term)
intoGenGPR161
Cancer3DGPR161(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612250   
Orphanet12620   
MedgenGPR161
Genetic Testing Registry GPR161
NextProtQ8N6U8 [Medical]
TSGene23432
GENETestsGPR161
Target ValidationGPR161
Huge Navigator GPR161 [HugePedia]
snp3D : Map Gene to Disease23432
BioCentury BCIQGPR161
ClinGenGPR161
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23432
Chemical/Pharm GKB GenePA134931474
Clinical trialGPR161
Miscellaneous
canSAR (ICR)GPR161 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPR161
EVEXGPR161
GoPubMedGPR161
iHOPGPR161
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:51:49 CET 2017

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