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GPR173 (G protein-coupled receptor 173)

Identity

Alias_namesG-protein coupled receptor 173
G protein coupled receptor 173
Alias_symbol (synonym)SREB3
Other alias
HGNC (Hugo) GPR173
LocusID (NCBI) 54328
Atlas_Id 63977
Location Xp11.22  [Link to chromosome band Xp11]
Location_base_pair Starts at 53049324 and ends at 53080614 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARMC2 (6q21) / GPR173 (Xp11.22)CGNL1 (15q21.3) / GPR173 (Xp11.22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPR173   18186
Cards
Entrez_Gene (NCBI)GPR173  54328  G protein-coupled receptor 173
AliasesSREB3
GeneCards (Weizmann)GPR173
Ensembl hg19 (Hinxton)ENSG00000184194 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184194 [Gene_View]  chrX:53049324-53080614 [Contig_View]  GPR173 [Vega]
ICGC DataPortalENSG00000184194
TCGA cBioPortalGPR173
AceView (NCBI)GPR173
Genatlas (Paris)GPR173
WikiGenes54328
SOURCE (Princeton)GPR173
Genetics Home Reference (NIH)GPR173
Genomic and cartography
GoldenPath hg38 (UCSC)GPR173  -     chrX:53049324-53080614 +  Xp11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR173  -     Xp11.22   [Description]    (hg19-Feb_2009)
EnsemblGPR173 - Xp11.22 [CytoView hg19]  GPR173 - Xp11.22 [CytoView hg38]
Mapping of homologs : NCBIGPR173 [Mapview hg19]  GPR173 [Mapview hg38]
OMIM300253   
Gene and transcription
Genbank (Entrez)AB040801 BC009861 BC013072 BI602566 BM670611
RefSeq transcript (Entrez)NM_018969
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPR173
Cluster EST : UnigeneHs.193011 [ NCBI ]
CGAP (NCI)Hs.193011
Alternative Splicing GalleryENSG00000184194
Gene ExpressionGPR173 [ NCBI-GEO ]   GPR173 [ EBI - ARRAY_EXPRESS ]   GPR173 [ SEEK ]   GPR173 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR173 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54328
GTEX Portal (Tissue expression)GPR173
Human Protein AtlasENSG00000184194-GPR173 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NS66   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NS66  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NS66
Splice isoforms : SwissVarQ9NS66
PhosPhoSitePlusQ9NS66
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)GPR173
DMDM Disease mutations54328
Blocks (Seattle)GPR173
SuperfamilyQ9NS66
Human Protein Atlas [tissue]ENSG00000184194-GPR173 [tissue]
Peptide AtlasQ9NS66
HPRD02220
IPIIPI00016900   IPI01025336   
Protein Interaction databases
DIP (DOE-UCLA)Q9NS66
IntAct (EBI)Q9NS66
FunCoupENSG00000184194
BioGRIDGPR173
STRING (EMBL)GPR173
ZODIACGPR173
Ontologies - Pathways
QuickGOQ9NS66
Ontology : AmiGOG-protein coupled receptor activity  gonadotropin-releasing hormone receptor activity  plasma membrane  signal transduction  G-protein coupled receptor signaling pathway  integral component of membrane  cellular response to gonadotropin-releasing hormone  negative regulation of neuron migration  
Ontology : EGO-EBIG-protein coupled receptor activity  gonadotropin-releasing hormone receptor activity  plasma membrane  signal transduction  G-protein coupled receptor signaling pathway  integral component of membrane  cellular response to gonadotropin-releasing hormone  negative regulation of neuron migration  
NDEx NetworkGPR173
Atlas of Cancer Signalling NetworkGPR173
Wikipedia pathwaysGPR173
Orthology - Evolution
OrthoDB54328
GeneTree (enSembl)ENSG00000184194
Phylogenetic Trees/Animal Genes : TreeFamGPR173
HOVERGENQ9NS66
HOGENOMQ9NS66
Homologs : HomoloGeneGPR173
Homology/Alignments : Family Browser (UCSC)GPR173
Gene fusions - Rearrangements
Tumor Fusion PortalGPR173
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR173 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR173
dbVarGPR173
ClinVarGPR173
1000_GenomesGPR173 
Exome Variant ServerGPR173
ExAC (Exome Aggregation Consortium)ENSG00000184194
GNOMAD BrowserENSG00000184194
Genetic variants : HAPMAP54328
Genomic Variants (DGV)GPR173 [DGVbeta]
DECIPHERGPR173 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR173 
Mutations
ICGC Data PortalGPR173 
TCGA Data PortalGPR173 
Broad Tumor PortalGPR173
OASIS PortalGPR173 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR173  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPR173
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch GPR173
DgiDB (Drug Gene Interaction Database)GPR173
DoCM (Curated mutations)GPR173 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPR173 (select a term)
intoGenGPR173
Cancer3DGPR173(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300253   
Orphanet
DisGeNETGPR173
MedgenGPR173
Genetic Testing Registry GPR173
NextProtQ9NS66 [Medical]
TSGene54328
GENETestsGPR173
Target ValidationGPR173
Huge Navigator GPR173 [HugePedia]
snp3D : Map Gene to Disease54328
BioCentury BCIQGPR173
ClinGenGPR173
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54328
Chemical/Pharm GKB GenePA134896710
Clinical trialGPR173
Miscellaneous
canSAR (ICR)GPR173 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPR173
EVEXGPR173
GoPubMedGPR173
iHOPGPR173
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 19:31:46 CET 2017

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