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GPR18 (G protein-coupled receptor 18)

Identity

Other alias-
HGNC (Hugo) GPR18
LocusID (NCBI) 2841
Atlas_Id 52180
Location 13q32.3  [Link to chromosome band 13q32]
Location_base_pair Starts at 99254713 and ends at 99258428 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPR18   4472
Cards
Entrez_Gene (NCBI)GPR18  2841  G protein-coupled receptor 18
Aliases
GeneCards (Weizmann)GPR18
Ensembl hg19 (Hinxton)ENSG00000125245 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000125245 [Gene_View]  chr13:99254713-99258428 [Contig_View]  GPR18 [Vega]
ICGC DataPortalENSG00000125245
TCGA cBioPortalGPR18
AceView (NCBI)GPR18
Genatlas (Paris)GPR18
WikiGenes2841
SOURCE (Princeton)GPR18
Genetics Home Reference (NIH)GPR18
Genomic and cartography
GoldenPath hg38 (UCSC)GPR18  -     chr13:99254713-99258428 -  13q32.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR18  -     13q32.3   [Description]    (hg19-Feb_2009)
EnsemblGPR18 - 13q32.3 [CytoView hg19]  GPR18 - 13q32.3 [CytoView hg38]
Mapping of homologs : NCBIGPR18 [Mapview hg19]  GPR18 [Mapview hg38]
OMIM602042   
Gene and transcription
Genbank (Entrez)AA825595 AF261135 AF339781 BC008569 BC050646
RefSeq transcript (Entrez)NM_001098200 NM_005292
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPR18
Cluster EST : UnigeneHs.741589 [ NCBI ]
CGAP (NCI)Hs.741589
Alternative Splicing GalleryENSG00000125245
Gene ExpressionGPR18 [ NCBI-GEO ]   GPR18 [ EBI - ARRAY_EXPRESS ]   GPR18 [ SEEK ]   GPR18 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR18 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2841
GTEX Portal (Tissue expression)GPR18
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14330   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14330  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14330
Splice isoforms : SwissVarQ14330
PhosPhoSitePlusQ14330
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    GPR18   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)GPR18
DMDM Disease mutations2841
Blocks (Seattle)GPR18
SuperfamilyQ14330
Human Protein AtlasENSG00000125245
Peptide AtlasQ14330
HPRD03621
IPIIPI00555618   IPI00640571   
Protein Interaction databases
DIP (DOE-UCLA)Q14330
IntAct (EBI)Q14330
FunCoupENSG00000125245
BioGRIDGPR18
STRING (EMBL)GPR18
ZODIACGPR18
Ontologies - Pathways
QuickGOQ14330
Ontology : AmiGOCD8-positive, alpha-beta intraepithelial T cell differentiation  CD8-positive, gamma-delta intraepithelial T cell differentiation  negative regulation of leukocyte chemotaxis  G-protein coupled receptor activity  G-protein coupled receptor activity  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  integral component of membrane  T cell differentiation  cytoplasmic vesicle membrane  negative regulation of tumor necrosis factor production  positive regulation of Rho protein signal transduction  positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway  
Ontology : EGO-EBICD8-positive, alpha-beta intraepithelial T cell differentiation  CD8-positive, gamma-delta intraepithelial T cell differentiation  negative regulation of leukocyte chemotaxis  G-protein coupled receptor activity  G-protein coupled receptor activity  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  integral component of membrane  T cell differentiation  cytoplasmic vesicle membrane  negative regulation of tumor necrosis factor production  positive regulation of Rho protein signal transduction  positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway  
NDEx NetworkGPR18
Atlas of Cancer Signalling NetworkGPR18
Wikipedia pathwaysGPR18
Orthology - Evolution
OrthoDB2841
GeneTree (enSembl)ENSG00000125245
Phylogenetic Trees/Animal Genes : TreeFamGPR18
HOVERGENQ14330
HOGENOMQ14330
Homologs : HomoloGeneGPR18
Homology/Alignments : Family Browser (UCSC)GPR18
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR18 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR18
dbVarGPR18
ClinVarGPR18
1000_GenomesGPR18 
Exome Variant ServerGPR18
ExAC (Exome Aggregation Consortium)GPR18 (select the gene name)
Genetic variants : HAPMAP2841
Genomic Variants (DGV)GPR18 [DGVbeta]
DECIPHERGPR18 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR18 
Mutations
ICGC Data PortalGPR18 
TCGA Data PortalGPR18 
Broad Tumor PortalGPR18
OASIS PortalGPR18 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR18  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPR18
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPR18
DgiDB (Drug Gene Interaction Database)GPR18
DoCM (Curated mutations)GPR18 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPR18 (select a term)
intoGenGPR18
Cancer3DGPR18(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602042   
Orphanet
MedgenGPR18
Genetic Testing Registry GPR18
NextProtQ14330 [Medical]
TSGene2841
GENETestsGPR18
Huge Navigator GPR18 [HugePedia]
snp3D : Map Gene to Disease2841
BioCentury BCIQGPR18
ClinGenGPR18
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2841
Chemical/Pharm GKB GenePA28860
Clinical trialGPR18
Miscellaneous
canSAR (ICR)GPR18 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPR18
EVEXGPR18
GoPubMedGPR18
iHOPGPR18
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:17:49 CEST 2017

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