Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GPR21 (G protein-coupled receptor 21)

Identity

Other alias-
HGNC (Hugo) GPR21
LocusID (NCBI) 2844
Atlas_Id 63985
Location 9q33.2  [Link to chromosome band 9q33]
Location_base_pair Starts at 123033643 and ends at 123035665 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPR21   4476
Cards
Entrez_Gene (NCBI)GPR21  2844  G protein-coupled receptor 21
Aliases
GeneCards (Weizmann)GPR21
Ensembl hg19 (Hinxton)ENSG00000011454 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000011454 [Gene_View]  chr9:123033643-123035665 [Contig_View]  GPR21 [Vega]
ICGC DataPortalENSG00000011454
TCGA cBioPortalGPR21
AceView (NCBI)GPR21
Genatlas (Paris)GPR21
WikiGenes2844
SOURCE (Princeton)GPR21
Genetics Home Reference (NIH)GPR21
Genomic and cartography
GoldenPath hg38 (UCSC)GPR21  -     chr9:123033643-123035665 +  9q33.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR21  -     9q33.2   [Description]    (hg19-Feb_2009)
EnsemblGPR21 - 9q33.2 [CytoView hg19]  GPR21 - 9q33.2 [CytoView hg38]
Mapping of homologs : NCBIGPR21 [Mapview hg19]  GPR21 [Mapview hg38]
OMIM601909   
Gene and transcription
Genbank (Entrez)AK299686 AK313539 BC066885 BC066886 BC067532
RefSeq transcript (Entrez)NM_005294
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPR21
Cluster EST : UnigeneHs.722039 [ NCBI ]
CGAP (NCI)Hs.722039
Alternative Splicing GalleryENSG00000011454
Gene ExpressionGPR21 [ NCBI-GEO ]   GPR21 [ EBI - ARRAY_EXPRESS ]   GPR21 [ SEEK ]   GPR21 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR21 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2844
GTEX Portal (Tissue expression)GPR21
Human Protein AtlasENSG00000011454-GPR21 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99679   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99679  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99679
Splice isoforms : SwissVarQ99679
PhosPhoSitePlusQ99679
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)GPR21
DMDM Disease mutations2844
Blocks (Seattle)GPR21
SuperfamilyQ99679
Human Protein Atlas [tissue]ENSG00000011454-GPR21 [tissue]
Peptide AtlasQ99679
HPRD03551
IPIIPI00017043   IPI01012596   
Protein Interaction databases
DIP (DOE-UCLA)Q99679
IntAct (EBI)Q99679
FunCoupENSG00000011454
BioGRIDGPR21
STRING (EMBL)GPR21
ZODIACGPR21
Ontologies - Pathways
QuickGOQ99679
Ontology : AmiGOdopamine neurotransmitter receptor activity, coupled via Gs  plasma membrane  dopamine receptor signaling pathway  integral component of membrane  positive regulation of multicellular organism growth  glucose homeostasis  negative regulation of insulin receptor signaling pathway  
Ontology : EGO-EBIdopamine neurotransmitter receptor activity, coupled via Gs  plasma membrane  dopamine receptor signaling pathway  integral component of membrane  positive regulation of multicellular organism growth  glucose homeostasis  negative regulation of insulin receptor signaling pathway  
NDEx NetworkGPR21
Atlas of Cancer Signalling NetworkGPR21
Wikipedia pathwaysGPR21
Orthology - Evolution
OrthoDB2844
GeneTree (enSembl)ENSG00000011454
Phylogenetic Trees/Animal Genes : TreeFamGPR21
HOVERGENQ99679
HOGENOMQ99679
Homologs : HomoloGeneGPR21
Homology/Alignments : Family Browser (UCSC)GPR21
Gene fusions - Rearrangements
Tumor Fusion PortalGPR21
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR21
dbVarGPR21
ClinVarGPR21
1000_GenomesGPR21 
Exome Variant ServerGPR21
ExAC (Exome Aggregation Consortium)ENSG00000011454
GNOMAD BrowserENSG00000011454
Genetic variants : HAPMAP2844
Genomic Variants (DGV)GPR21 [DGVbeta]
DECIPHERGPR21 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR21 
Mutations
ICGC Data PortalGPR21 
TCGA Data PortalGPR21 
Broad Tumor PortalGPR21
OASIS PortalGPR21 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR21  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPR21
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPR21
DgiDB (Drug Gene Interaction Database)GPR21
DoCM (Curated mutations)GPR21 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPR21 (select a term)
intoGenGPR21
Cancer3DGPR21(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601909   
Orphanet
DisGeNETGPR21
MedgenGPR21
Genetic Testing Registry GPR21
NextProtQ99679 [Medical]
TSGene2844
GENETestsGPR21
Target ValidationGPR21
Huge Navigator GPR21 [HugePedia]
snp3D : Map Gene to Disease2844
BioCentury BCIQGPR21
ClinGenGPR21
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2844
Chemical/Pharm GKB GenePA28864
Clinical trialGPR21
Miscellaneous
canSAR (ICR)GPR21 (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPR21
EVEXGPR21
GoPubMedGPR21
iHOPGPR21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:19:51 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.