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GPR27 (G protein-coupled receptor 27)

Identity

Alias_symbol (synonym)SREB1
Other alias
HGNC (Hugo) GPR27
LocusID (NCBI) 2850
Atlas_Id 63988
Location 3p13  [Link to chromosome band 3p13]
Location_base_pair Starts at 71753724 and ends at 71756380 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPR27   4482
Cards
Entrez_Gene (NCBI)GPR27  2850  G protein-coupled receptor 27
AliasesSREB1
GeneCards (Weizmann)GPR27
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr3:71753724-71756380 [Contig_View]  GPR27 [Vega]
TCGA cBioPortalGPR27
AceView (NCBI)GPR27
Genatlas (Paris)GPR27
WikiGenes2850
SOURCE (Princeton)GPR27
Genetics Home Reference (NIH)GPR27
Genomic and cartography
GoldenPath hg38 (UCSC)GPR27  -     chr3:71753724-71756380 +  3p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR27  -     3p13   [Description]    (hg19-Feb_2009)
EnsemblGPR27 - 3p13 [CytoView hg19]  GPR27 - 3p13 [CytoView hg38]
Mapping of homologs : NCBIGPR27 [Mapview hg19]  GPR27 [Mapview hg38]
OMIM605187   
Gene and transcription
Genbank (Entrez)AB040799 BC160129 HQ709187
RefSeq transcript (Entrez)NM_018971
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPR27
Cluster EST : UnigeneHs.591653 [ NCBI ]
CGAP (NCI)Hs.591653
Gene ExpressionGPR27 [ NCBI-GEO ]   GPR27 [ EBI - ARRAY_EXPRESS ]   GPR27 [ SEEK ]   GPR27 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR27 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2850
GTEX Portal (Tissue expression)GPR27
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NS67   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NS67  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NS67
Splice isoforms : SwissVarQ9NS67
PhosPhoSitePlusQ9NS67
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)GPR27
DMDM Disease mutations2850
Blocks (Seattle)GPR27
SuperfamilyQ9NS67
Peptide AtlasQ9NS67
HPRD05542
IPIIPI00016902   
Protein Interaction databases
DIP (DOE-UCLA)Q9NS67
IntAct (EBI)Q9NS67
BioGRIDGPR27
STRING (EMBL)GPR27
ZODIACGPR27
Ontologies - Pathways
QuickGOQ9NS67
Ontology : AmiGOG-protein coupled receptor activity  plasma membrane  plasma membrane  signal transduction  G-protein coupled receptor signaling pathway  integral component of membrane  positive regulation of insulin secretion involved in cellular response to glucose stimulus  positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway  
Ontology : EGO-EBIG-protein coupled receptor activity  plasma membrane  plasma membrane  signal transduction  G-protein coupled receptor signaling pathway  integral component of membrane  positive regulation of insulin secretion involved in cellular response to glucose stimulus  positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway  
NDEx NetworkGPR27
Atlas of Cancer Signalling NetworkGPR27
Wikipedia pathwaysGPR27
Orthology - Evolution
OrthoDB2850
Phylogenetic Trees/Animal Genes : TreeFamGPR27
HOVERGENQ9NS67
HOGENOMQ9NS67
Homologs : HomoloGeneGPR27
Homology/Alignments : Family Browser (UCSC)GPR27
Gene fusions - Rearrangements
Fusion: Tumor Portal GPR27
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR27 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR27
dbVarGPR27
ClinVarGPR27
1000_GenomesGPR27 
Exome Variant ServerGPR27
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP2850
Genomic Variants (DGV)GPR27 [DGVbeta]
DECIPHERGPR27 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR27 
Mutations
ICGC Data PortalGPR27 
TCGA Data PortalGPR27 
Broad Tumor PortalGPR27
OASIS PortalGPR27 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR27  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPR27
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPR27
DgiDB (Drug Gene Interaction Database)GPR27
DoCM (Curated mutations)GPR27 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPR27 (select a term)
intoGenGPR27
Cancer3DGPR27(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605187   
Orphanet
MedgenGPR27
Genetic Testing Registry GPR27
NextProtQ9NS67 [Medical]
TSGene2850
GENETestsGPR27
Target ValidationGPR27
Huge Navigator GPR27 [HugePedia]
snp3D : Map Gene to Disease2850
BioCentury BCIQGPR27
ClinGenGPR27
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2850
Chemical/Pharm GKB GenePA28870
Clinical trialGPR27
Miscellaneous
canSAR (ICR)GPR27 (select the gene name)
Probes
Litterature
PubMed2 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPR27
EVEXGPR27
GoPubMedGPR27
iHOPGPR27
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 11:49:35 CET 2017

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