GPR3 (G protein-coupled receptor 3)

2014-11-01  

Identity

HGNC
LOCATION
1p36.11
LOCUSID
ALIAS
ACCA

Other Information

Locus ID:

NCBI: 2827
MIM: 600241
HGNC: 4484
Ensembl: ENSG00000181773

Variants:

dbSNP: 2827
ClinVar: 2827
TCGA: ENSG00000181773
COSMIC: GPR3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000181773ENST00000374024P46089
ENSG00000181773ENST00000374024F1DAM5

Expression (GTEx)

0
1
2
3
4
5
6
7

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
155912062004The Gs-linked receptor GPR3 maintains meiotic arrest in mammalian oocytes.107
240693302013Gpr3 stimulates Aβ production via interactions with APP and β-arrestin2.13
126495922003Fluid shear stress differentially regulates gpr3, gpr6, and gpr12 expression in human umbilical vein endothelial cells.8
179539672008Oocyte-specific G-protein-coupled receptor 3 (GPR3): no perturbations found in 82 women with premature ovarian failure (first report).6
179539672008Oocyte-specific G-protein-coupled receptor 3 (GPR3): no perturbations found in 82 women with premature ovarian failure (first report).6
201589882010GPR3 may not be a potential candidate gene for premature ovarian failure.4
300383192018Allosteric sodium binding cavity in GPR3: a novel player in modulation of Aβ production.3
237326632013[G protein-coupled receptor 3: a key factor in the regulation of the nervous system and follicle development].0
238260792013Regulation of Constitutive GPR3 Signaling and Surface Localization by GRK2 and β-arrestin-2 Overexpression in HEK293 Cells.0

Citation

Dessen P

GPR3 (G protein-coupled receptor 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63989/gpr3