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GPR34 (G protein-coupled receptor 34)

Identity

Other aliasLYPSR1
HGNC (Hugo) GPR34
LocusID (NCBI) 2857
Atlas_Id 53155
Location Xp11.4  [Link to chromosome band Xp11]
Location_base_pair Starts at 41688973 and ends at 41697277 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
IGH (14q32.33) / GPR34 (Xp11.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(X;14)(p11.4;q32.33) IGH/GPR34


External links

Nomenclature
HGNC (Hugo)GPR34   4490
Cards
Entrez_Gene (NCBI)GPR34  2857  G protein-coupled receptor 34
AliasesLYPSR1
GeneCards (Weizmann)GPR34
Ensembl hg19 (Hinxton)ENSG00000171659 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171659 [Gene_View]  chrX:41688973-41697277 [Contig_View]  GPR34 [Vega]
ICGC DataPortalENSG00000171659
TCGA cBioPortalGPR34
AceView (NCBI)GPR34
Genatlas (Paris)GPR34
WikiGenes2857
SOURCE (Princeton)GPR34
Genetics Home Reference (NIH)GPR34
Genomic and cartography
GoldenPath hg38 (UCSC)GPR34  -     chrX:41688973-41697277 +  Xp11.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR34  -     Xp11.4   [Description]    (hg19-Feb_2009)
EnsemblGPR34 - Xp11.4 [CytoView hg19]  GPR34 - Xp11.4 [CytoView hg38]
Mapping of homologs : NCBIGPR34 [Mapview hg19]  GPR34 [Mapview hg38]
OMIM300241   
Gene and transcription
Genbank (Entrez)AA130392 AF039686 AK027780 AK074627 AK075217
RefSeq transcript (Entrez)NM_001033513 NM_001033514 NM_001097579 NM_005300
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPR34
Cluster EST : UnigeneHs.495989 [ NCBI ]
CGAP (NCI)Hs.495989
Alternative Splicing GalleryENSG00000171659
Gene ExpressionGPR34 [ NCBI-GEO ]   GPR34 [ EBI - ARRAY_EXPRESS ]   GPR34 [ SEEK ]   GPR34 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR34 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2857
GTEX Portal (Tissue expression)GPR34
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UPC5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UPC5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UPC5
Splice isoforms : SwissVarQ9UPC5
PhosPhoSitePlusQ9UPC5
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)GPR34
DMDM Disease mutations2857
Blocks (Seattle)GPR34
SuperfamilyQ9UPC5
Human Protein AtlasENSG00000171659
Peptide AtlasQ9UPC5
HPRD02213
IPIIPI00010051   IPI01009575   
Protein Interaction databases
DIP (DOE-UCLA)Q9UPC5
IntAct (EBI)Q9UPC5
FunCoupENSG00000171659
BioGRIDGPR34
STRING (EMBL)GPR34
ZODIACGPR34
Ontologies - Pathways
QuickGOQ9UPC5
Ontology : AmiGOG-protein coupled receptor activity  integral component of plasma membrane  G-protein coupled receptor signaling pathway  G-protein coupled purinergic nucleotide receptor signaling pathway  G-protein coupled purinergic nucleotide receptor activity  
Ontology : EGO-EBIG-protein coupled receptor activity  integral component of plasma membrane  G-protein coupled receptor signaling pathway  G-protein coupled purinergic nucleotide receptor signaling pathway  G-protein coupled purinergic nucleotide receptor activity  
NDEx NetworkGPR34
Atlas of Cancer Signalling NetworkGPR34
Wikipedia pathwaysGPR34
Orthology - Evolution
OrthoDB2857
GeneTree (enSembl)ENSG00000171659
Phylogenetic Trees/Animal Genes : TreeFamGPR34
HOVERGENQ9UPC5
HOGENOMQ9UPC5
Homologs : HomoloGeneGPR34
Homology/Alignments : Family Browser (UCSC)GPR34
Gene fusions - Rearrangements
Fusion : MitelmanIGH/GPR34 [14q32.33/Xp11.4]  [t(X;14)(p11;q32)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR34 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR34
dbVarGPR34
ClinVarGPR34
1000_GenomesGPR34 
Exome Variant ServerGPR34
ExAC (Exome Aggregation Consortium)GPR34 (select the gene name)
Genetic variants : HAPMAP2857
Genomic Variants (DGV)GPR34 [DGVbeta]
DECIPHERGPR34 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR34 
Mutations
ICGC Data PortalGPR34 
TCGA Data PortalGPR34 
Broad Tumor PortalGPR34
OASIS PortalGPR34 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR34  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPR34
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPR34
DgiDB (Drug Gene Interaction Database)GPR34
DoCM (Curated mutations)GPR34 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPR34 (select a term)
intoGenGPR34
Cancer3DGPR34(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300241   
Orphanet
MedgenGPR34
Genetic Testing Registry GPR34
NextProtQ9UPC5 [Medical]
TSGene2857
GENETestsGPR34
Target ValidationGPR34
Huge Navigator GPR34 [HugePedia]
snp3D : Map Gene to Disease2857
BioCentury BCIQGPR34
ClinGenGPR34
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2857
Chemical/Pharm GKB GenePA28878
Clinical trialGPR34
Miscellaneous
canSAR (ICR)GPR34 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPR34
EVEXGPR34
GoPubMedGPR34
iHOPGPR34
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:02:24 CEST 2017

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