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GPR35 (G protein-coupled receptor 35)

Identity

Other alias-
HGNC (Hugo) GPR35
LocusID (NCBI) 2859
Atlas_Id 63993
Location 2q37.3  [Link to chromosome band 2q37]
Location_base_pair Starts at 240605408 and ends at 240631259 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CAPN10 (2q37.3) / GPR35 (2q37.3)GPR35 (2q37.3) / MELK (9p13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPR35   4492
Cards
Entrez_Gene (NCBI)GPR35  2859  G protein-coupled receptor 35
Aliases
GeneCards (Weizmann)GPR35
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr2:240605408-240631259 [Contig_View]  GPR35 [Vega]
TCGA cBioPortalGPR35
AceView (NCBI)GPR35
Genatlas (Paris)GPR35
WikiGenes2859
SOURCE (Princeton)GPR35
Genetics Home Reference (NIH)GPR35
Genomic and cartography
GoldenPath hg38 (UCSC)GPR35  -     chr2:240605408-240631259 +  2q37.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR35  -     2q37.3   [Description]    (hg19-Feb_2009)
EnsemblGPR35 - 2q37.3 [CytoView hg19]  GPR35 - 2q37.3 [CytoView hg38]
Mapping of homologs : NCBIGPR35 [Mapview hg19]  GPR35 [Mapview hg38]
OMIM602646   
Gene and transcription
Genbank (Entrez)AF089087 AK131540 AK172786 AK290256 AK314002
RefSeq transcript (Entrez)NM_001195381 NM_001195382 NM_005301
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPR35
Cluster EST : UnigeneHs.112218 [ NCBI ]
CGAP (NCI)Hs.112218
Gene ExpressionGPR35 [ NCBI-GEO ]   GPR35 [ EBI - ARRAY_EXPRESS ]   GPR35 [ SEEK ]   GPR35 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR35 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2859
GTEX Portal (Tissue expression)GPR35
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HC97   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HC97  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HC97
Splice isoforms : SwissVarQ9HC97
PhosPhoSitePlusQ9HC97
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)GPR35
DMDM Disease mutations2859
Blocks (Seattle)GPR35
SuperfamilyQ9HC97
Peptide AtlasQ9HC97
HPRD16003
IPIIPI00943284   IPI00030217   IPI00867521   
Protein Interaction databases
DIP (DOE-UCLA)Q9HC97
IntAct (EBI)Q9HC97
BioGRIDGPR35
STRING (EMBL)GPR35
ZODIACGPR35
Ontologies - Pathways
QuickGOQ9HC97
Ontology : AmiGOG-protein coupled receptor activity  plasma membrane  integral component of plasma membrane  cytoskeleton organization  G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  C-X-C chemokine receptor activity  positive regulation of Rho protein signal transduction  positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway  chemokine-mediated signaling pathway  chemokine-mediated signaling pathway  negative regulation of voltage-gated calcium channel activity  negative regulation of neuronal action potential  
Ontology : EGO-EBIG-protein coupled receptor activity  plasma membrane  integral component of plasma membrane  cytoskeleton organization  G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  C-X-C chemokine receptor activity  positive regulation of Rho protein signal transduction  positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway  chemokine-mediated signaling pathway  chemokine-mediated signaling pathway  negative regulation of voltage-gated calcium channel activity  negative regulation of neuronal action potential  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkGPR35
Atlas of Cancer Signalling NetworkGPR35
Wikipedia pathwaysGPR35
Orthology - Evolution
OrthoDB2859
Phylogenetic Trees/Animal Genes : TreeFamGPR35
HOVERGENQ9HC97
HOGENOMQ9HC97
Homologs : HomoloGeneGPR35
Homology/Alignments : Family Browser (UCSC)GPR35
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR35 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR35
dbVarGPR35
ClinVarGPR35
1000_GenomesGPR35 
Exome Variant ServerGPR35
ExAC (Exome Aggregation Consortium)GPR35 (select the gene name)
Genetic variants : HAPMAP2859
Genomic Variants (DGV)GPR35 [DGVbeta]
DECIPHERGPR35 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR35 
Mutations
ICGC Data PortalGPR35 
TCGA Data PortalGPR35 
Broad Tumor PortalGPR35
OASIS PortalGPR35 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR35  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPR35
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPR35
DgiDB (Drug Gene Interaction Database)GPR35
DoCM (Curated mutations)GPR35 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPR35 (select a term)
intoGenGPR35
Cancer3DGPR35(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602646   
Orphanet783   
MedgenGPR35
Genetic Testing Registry GPR35
NextProtQ9HC97 [Medical]
TSGene2859
GENETestsGPR35
Target ValidationGPR35
Huge Navigator GPR35 [HugePedia]
snp3D : Map Gene to Disease2859
BioCentury BCIQGPR35
ClinGenGPR35
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2859
Chemical/Pharm GKB GenePA28880
Clinical trialGPR35
Miscellaneous
canSAR (ICR)GPR35 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPR35
EVEXGPR35
GoPubMedGPR35
iHOPGPR35
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:51:17 CEST 2017

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