GPR37L1 (G protein-coupled receptor 37 like 1)

2016-10-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
ET(B)R-LP-2,ETBR-LP-2,ETBRLP2
FUSION GENES

Other Information

Locus ID:

NCBI: 9283
MIM: 617630
HGNC: 14923
Ensembl: ENSG00000170075

Variants:

dbSNP: 9283
ClinVar: 9283
TCGA: ENSG00000170075
COSMIC: GPR37L1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170075ENST00000367282O60883

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
236905942013GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin.56
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
203608442010Genome-wide association study identifies GPC5 as a novel genetic locus protective against sudden cardiac arrest.21
270726552016Metalloprotease cleavage of the N terminus of the orphan G protein-coupled receptor GPR37L1 reduces its constitutive activity.10
286888532017GPR37L1 modulates seizure susceptibility: Evidence from mouse studies and analyses of a human GPR37L1 variant.6
304232892019GPR37 and GPR37L1 differently interact with dopamine 2 receptors in live cells.0

Citation

Dessen P

GPR37L1 (G protein-coupled receptor 37 like 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56441/gpr37l1