Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GPR37L1 (G protein-coupled receptor 37 like 1)

Identity

Alias_symbol (synonym)ETBR-LP-2
Other aliasET(B)R-LP-2
ETBRLP2
HGNC (Hugo) GPR37L1
LocusID (NCBI) 9283
Atlas_Id 56441
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 202122841 and ends at 202133588 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GPR37L1 (1q32.1) / PLXNB3 (Xq28)LGR6 (1q32.1) / GPR37L1 (1q32.1)TESK2 (1p34.1) / GPR37L1 (1q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(1;1)(p34;q32) TESK2/GPR37L1
LGR6/GPR37L1 (1q32)


External links

Nomenclature
HGNC (Hugo)GPR37L1   14923
Cards
Entrez_Gene (NCBI)GPR37L1  9283  G protein-coupled receptor 37 like 1
AliasesET(B)R-LP-2; ETBR-LP-2; ETBRLP2
GeneCards (Weizmann)GPR37L1
Ensembl hg19 (Hinxton)ENSG00000170075 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170075 [Gene_View]  ENSG00000170075 [Sequence]  chr1:202122841-202133588 [Contig_View]  GPR37L1 [Vega]
ICGC DataPortalENSG00000170075
TCGA cBioPortalGPR37L1
AceView (NCBI)GPR37L1
Genatlas (Paris)GPR37L1
WikiGenes9283
SOURCE (Princeton)GPR37L1
Genetics Home Reference (NIH)GPR37L1
Genomic and cartography
GoldenPath hg38 (UCSC)GPR37L1  -     chr1:202122841-202133588 +  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR37L1  -     1q32.1   [Description]    (hg19-Feb_2009)
EnsemblGPR37L1 - 1q32.1 [CytoView hg19]  GPR37L1 - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBIGPR37L1 [Mapview hg19]  GPR37L1 [Mapview hg38]
OMIM617630   
Gene and transcription
Genbank (Entrez)AK222639 AK295576 AK313044 AL050068 BC050334
RefSeq transcript (Entrez)NM_004767
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPR37L1
Cluster EST : UnigeneHs.604697 [ NCBI ]
CGAP (NCI)Hs.604697
Alternative Splicing GalleryENSG00000170075
Gene ExpressionGPR37L1 [ NCBI-GEO ]   GPR37L1 [ EBI - ARRAY_EXPRESS ]   GPR37L1 [ SEEK ]   GPR37L1 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR37L1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9283
GTEX Portal (Tissue expression)GPR37L1
Human Protein AtlasENSG00000170075-GPR37L1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60883   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60883  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60883
Splice isoforms : SwissVarO60883
PhosPhoSitePlusO60883
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    GPR37_orph   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)GPR37L1
DMDM Disease mutations9283
Blocks (Seattle)GPR37L1
SuperfamilyO60883
Human Protein Atlas [tissue]ENSG00000170075-GPR37L1 [tissue]
Peptide AtlasO60883
HPRD13603
IPIIPI00032405   IPI01009210   
Protein Interaction databases
DIP (DOE-UCLA)O60883
IntAct (EBI)O60883
FunCoupENSG00000170075
BioGRIDGPR37L1
STRING (EMBL)GPR37L1
ZODIACGPR37L1
Ontologies - Pathways
QuickGOO60883
Ontology : AmiGOnegative regulation of systemic arterial blood pressure  G protein-coupled receptor activity  protein binding  plasma membrane  plasma membrane  G protein-coupled receptor signaling pathway  adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway  G protein-coupled peptide receptor activity  integral component of membrane  positive regulation of cerebellar granule cell precursor proliferation  prosaposin receptor activity  prosaposin receptor activity  peptide binding  receptor complex  positive regulation of MAPK cascade  negative regulation of neuron differentiation  negative regulation of smoothened signaling pathway  negative regulation of astrocyte differentiation  negative regulation of hydrogen peroxide-induced cell death  
Ontology : EGO-EBInegative regulation of systemic arterial blood pressure  G protein-coupled receptor activity  protein binding  plasma membrane  plasma membrane  G protein-coupled receptor signaling pathway  adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway  G protein-coupled peptide receptor activity  integral component of membrane  positive regulation of cerebellar granule cell precursor proliferation  prosaposin receptor activity  prosaposin receptor activity  peptide binding  receptor complex  positive regulation of MAPK cascade  negative regulation of neuron differentiation  negative regulation of smoothened signaling pathway  negative regulation of astrocyte differentiation  negative regulation of hydrogen peroxide-induced cell death  
NDEx NetworkGPR37L1
Atlas of Cancer Signalling NetworkGPR37L1
Wikipedia pathwaysGPR37L1
Orthology - Evolution
OrthoDB9283
GeneTree (enSembl)ENSG00000170075
Phylogenetic Trees/Animal Genes : TreeFamGPR37L1
HOVERGENO60883
HOGENOMO60883
Homologs : HomoloGeneGPR37L1
Homology/Alignments : Family Browser (UCSC)GPR37L1
Gene fusions - Rearrangements
Fusion : QuiverGPR37L1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR37L1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR37L1
dbVarGPR37L1
ClinVarGPR37L1
1000_GenomesGPR37L1 
Exome Variant ServerGPR37L1
ExAC (Exome Aggregation Consortium)ENSG00000170075
GNOMAD BrowserENSG00000170075
Varsome BrowserGPR37L1
Genetic variants : HAPMAP9283
Genomic Variants (DGV)GPR37L1 [DGVbeta]
DECIPHERGPR37L1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR37L1 
Mutations
ICGC Data PortalGPR37L1 
TCGA Data PortalGPR37L1 
Broad Tumor PortalGPR37L1
OASIS PortalGPR37L1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR37L1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPR37L1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPR37L1
DgiDB (Drug Gene Interaction Database)GPR37L1
DoCM (Curated mutations)GPR37L1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPR37L1 (select a term)
intoGenGPR37L1
Cancer3DGPR37L1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617630   
Orphanet
DisGeNETGPR37L1
MedgenGPR37L1
Genetic Testing Registry GPR37L1
NextProtO60883 [Medical]
TSGene9283
GENETestsGPR37L1
Target ValidationGPR37L1
Huge Navigator GPR37L1 [HugePedia]
snp3D : Map Gene to Disease9283
BioCentury BCIQGPR37L1
ClinGenGPR37L1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9283
Chemical/Pharm GKB GenePA28883
Clinical trialGPR37L1
Miscellaneous
canSAR (ICR)GPR37L1 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPR37L1
EVEXGPR37L1
GoPubMedGPR37L1
iHOPGPR37L1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:09:22 CET 2018

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