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GPR4 (G protein-coupled receptor 4)

Identity

Other alias-
HGNC (Hugo) GPR4
LocusID (NCBI) 2828
Atlas_Id 45722
Location 19q13.32  [Link to chromosome band 19q13]
Location_base_pair Starts at 46093023 and ends at 46105466 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPR4   4497
Cards
Entrez_Gene (NCBI)GPR4  2828  G protein-coupled receptor 4
Aliases
GeneCards (Weizmann)GPR4
Ensembl hg19 (Hinxton)ENSG00000177464 [Gene_View]  chr19:46093023-46105466 [Contig_View]  GPR4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000177464 [Gene_View]  chr19:46093023-46105466 [Contig_View]  GPR4 [Vega]
ICGC DataPortalENSG00000177464
TCGA cBioPortalGPR4
AceView (NCBI)GPR4
Genatlas (Paris)GPR4
WikiGenes2828
SOURCE (Princeton)GPR4
Genetics Home Reference (NIH)GPR4
Genomic and cartography
GoldenPath hg19 (UCSC)GPR4  -     chr19:46093023-46105466 -  19q13.32   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GPR4  -     19q13.32   [Description]    (hg38-Dec_2013)
EnsemblGPR4 - 19q13.32 [CytoView hg19]  GPR4 - 19q13.32 [CytoView hg38]
Mapping of homologs : NCBIGPR4 [Mapview hg19]  GPR4 [Mapview hg38]
OMIM600551   
Gene and transcription
Genbank (Entrez)AK290698 BC038450 BC067535 BC067536 BE669939
RefSeq transcript (Entrez)NM_005282
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)GPR4
Cluster EST : UnigeneHs.17170 [ NCBI ]
CGAP (NCI)Hs.17170
Alternative Splicing GalleryENSG00000177464
Gene ExpressionGPR4 [ NCBI-GEO ]   GPR4 [ EBI - ARRAY_EXPRESS ]   GPR4 [ SEEK ]   GPR4 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2828
GTEX Portal (Tissue expression)GPR4
Protein : pattern, domain, 3D structure
UniProt/SwissProtP46093   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP46093  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP46093
Splice isoforms : SwissVarP46093
PhosPhoSitePlusP46093
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    GPR4_orph   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)GPR4
DMDM Disease mutations2828
Blocks (Seattle)GPR4
SuperfamilyP46093
Human Protein AtlasENSG00000177464
Peptide AtlasP46093
HPRD02773
IPIIPI00004347   
Protein Interaction databases
DIP (DOE-UCLA)P46093
IntAct (EBI)P46093
FunCoupENSG00000177464
BioGRIDGPR4
STRING (EMBL)GPR4
ZODIACGPR4
Ontologies - Pathways
QuickGOP46093
Ontology : AmiGOG-protein coupled receptor activity  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  response to acidic pH  negative regulation of angiogenesis  angiogenesis involved in wound healing  glomerular mesangial cell development  
Ontology : EGO-EBIG-protein coupled receptor activity  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  response to acidic pH  negative regulation of angiogenesis  angiogenesis involved in wound healing  glomerular mesangial cell development  
NDEx NetworkGPR4
Atlas of Cancer Signalling NetworkGPR4
Wikipedia pathwaysGPR4
Orthology - Evolution
OrthoDB2828
GeneTree (enSembl)ENSG00000177464
Phylogenetic Trees/Animal Genes : TreeFamGPR4
HOVERGENP46093
HOGENOMP46093
Homologs : HomoloGeneGPR4
Homology/Alignments : Family Browser (UCSC)GPR4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR4
dbVarGPR4
ClinVarGPR4
1000_GenomesGPR4 
Exome Variant ServerGPR4
ExAC (Exome Aggregation Consortium)GPR4 (select the gene name)
Genetic variants : HAPMAP2828
Genomic Variants (DGV)GPR4 [DGVbeta]
DECIPHER (Syndromes)19:46093023-46105466  ENSG00000177464
CONAN: Copy Number AnalysisGPR4 
Mutations
ICGC Data PortalGPR4 
TCGA Data PortalGPR4 
Broad Tumor PortalGPR4
OASIS PortalGPR4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPR4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPR4
DgiDB (Drug Gene Interaction Database)GPR4
DoCM (Curated mutations)GPR4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPR4 (select a term)
intoGenGPR4
Cancer3DGPR4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600551   
Orphanet
MedgenGPR4
Genetic Testing Registry GPR4
NextProtP46093 [Medical]
TSGene2828
GENETestsGPR4
Huge Navigator GPR4 [HugePedia]
snp3D : Map Gene to Disease2828
BioCentury BCIQGPR4
ClinGenGPR4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2828
Chemical/Pharm GKB GenePA28886
Clinical trialGPR4
Miscellaneous
canSAR (ICR)GPR4 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPR4
EVEXGPR4
GoPubMedGPR4
iHOPGPR4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:08:04 CET 2017

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