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GPR45 (G protein-coupled receptor 45)

Identity

Alias_symbol (synonym)PSP24
PSP24A
Other aliasPSP24(ALPHA)
HGNC (Hugo) GPR45
LocusID (NCBI) 11250
Atlas_Id 63997
Location 2q12.1  [Link to chromosome band 2q12]
Location_base_pair Starts at 105241743 and ends at 105243467 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPR45   4503
Cards
Entrez_Gene (NCBI)GPR45  11250  G protein-coupled receptor 45
AliasesPSP24; PSP24(ALPHA); PSP24A
GeneCards (Weizmann)GPR45
Ensembl hg19 (Hinxton)ENSG00000135973 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135973 [Gene_View]  ENSG00000135973 [Sequence]  chr2:105241743-105243467 [Contig_View]  GPR45 [Vega]
ICGC DataPortalENSG00000135973
TCGA cBioPortalGPR45
AceView (NCBI)GPR45
Genatlas (Paris)GPR45
WikiGenes11250
SOURCE (Princeton)GPR45
Genetics Home Reference (NIH)GPR45
Genomic and cartography
GoldenPath hg38 (UCSC)GPR45  -     chr2:105241743-105243467 +  2q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR45  -     2q12.1   [Description]    (hg19-Feb_2009)
GoldenPathGPR45 - 2q12.1 [CytoView hg19]  GPR45 - 2q12.1 [CytoView hg38]
ImmunoBaseENSG00000135973
Mapping of homologs : NCBIGPR45 [Mapview hg19]  GPR45 [Mapview hg38]
OMIM604838   
Gene and transcription
Genbank (Entrez)BC066879 BC066880 BC067455 EU883573 U92642
RefSeq transcript (Entrez)NM_007227
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPR45
Cluster EST : UnigeneHs.590903 [ NCBI ]
CGAP (NCI)Hs.590903
Alternative Splicing GalleryENSG00000135973
Gene ExpressionGPR45 [ NCBI-GEO ]   GPR45 [ EBI - ARRAY_EXPRESS ]   GPR45 [ SEEK ]   GPR45 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR45 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11250
GTEX Portal (Tissue expression)GPR45
Human Protein AtlasENSG00000135973-GPR45 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5Y3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y5Y3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5Y3
Splice isoforms : SwissVarQ9Y5Y3
PhosPhoSitePlusQ9Y5Y3
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)GPR45
DMDM Disease mutations11250
Blocks (Seattle)GPR45
SuperfamilyQ9Y5Y3
Human Protein Atlas [tissue]ENSG00000135973-GPR45 [tissue]
Peptide AtlasQ9Y5Y3
HPRD05325
IPIIPI00419887   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5Y3
IntAct (EBI)Q9Y5Y3
FunCoupENSG00000135973
BioGRIDGPR45
STRING (EMBL)GPR45
ZODIACGPR45
Ontologies - Pathways
QuickGOQ9Y5Y3
Ontology : AmiGOG protein-coupled receptor activity  plasma membrane  G protein-coupled receptor signaling pathway  integral component of membrane  
Ontology : EGO-EBIG protein-coupled receptor activity  plasma membrane  G protein-coupled receptor signaling pathway  integral component of membrane  
NDEx NetworkGPR45
Atlas of Cancer Signalling NetworkGPR45
Wikipedia pathwaysGPR45
Orthology - Evolution
OrthoDB11250
GeneTree (enSembl)ENSG00000135973
Phylogenetic Trees/Animal Genes : TreeFamGPR45
HOGENOMQ9Y5Y3
Homologs : HomoloGeneGPR45
Homology/Alignments : Family Browser (UCSC)GPR45
Gene fusions - Rearrangements
Fusion : QuiverGPR45
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR45 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR45
dbVarGPR45
ClinVarGPR45
1000_GenomesGPR45 
Exome Variant ServerGPR45
ExAC (Exome Aggregation Consortium)ENSG00000135973
GNOMAD BrowserENSG00000135973
Varsome BrowserGPR45
Genetic variants : HAPMAP11250
Genomic Variants (DGV)GPR45 [DGVbeta]
DECIPHERGPR45 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR45 
Mutations
ICGC Data PortalGPR45 
TCGA Data PortalGPR45 
Broad Tumor PortalGPR45
OASIS PortalGPR45 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR45  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGPR45
Mutations and Diseases : HGMDGPR45
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPR45
DgiDB (Drug Gene Interaction Database)GPR45
DoCM (Curated mutations)GPR45 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPR45 (select a term)
intoGenGPR45
Cancer3DGPR45(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604838   
Orphanet
DisGeNETGPR45
MedgenGPR45
Genetic Testing Registry GPR45
NextProtQ9Y5Y3 [Medical]
TSGene11250
GENETestsGPR45
Target ValidationGPR45
Huge Navigator GPR45 [HugePedia]
snp3D : Map Gene to Disease11250
BioCentury BCIQGPR45
ClinGenGPR45
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11250
Chemical/Pharm GKB GenePA28892
Clinical trialGPR45
Miscellaneous
canSAR (ICR)GPR45 (select the gene name)
DataMed IndexGPR45
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPR45
EVEXGPR45
GoPubMedGPR45
iHOPGPR45
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Sep 3 15:30:13 CEST 2019

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