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GPR6 (G protein-coupled receptor 6)

Identity

Other alias-
HGNC (Hugo) GPR6
LocusID (NCBI) 2830
Atlas_Id 64000
Location 6q21  [Link to chromosome band 6q21]
Location_base_pair Starts at 109978256 and ends at 109980721 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPR6   4515
Cards
Entrez_Gene (NCBI)GPR6  2830  G protein-coupled receptor 6
Aliases
GeneCards (Weizmann)GPR6
Ensembl hg19 (Hinxton)ENSG00000146360 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146360 [Gene_View]  ENSG00000146360 [Sequence]  chr6:109978256-109980721 [Contig_View]  GPR6 [Vega]
ICGC DataPortalENSG00000146360
TCGA cBioPortalGPR6
AceView (NCBI)GPR6
Genatlas (Paris)GPR6
WikiGenes2830
SOURCE (Princeton)GPR6
Genetics Home Reference (NIH)GPR6
Genomic and cartography
GoldenPath hg38 (UCSC)GPR6  -     chr6:109978256-109980721 +  6q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR6  -     6q21   [Description]    (hg19-Feb_2009)
EnsemblGPR6 - 6q21 [CytoView hg19]  GPR6 - 6q21 [CytoView hg38]
Mapping of homologs : NCBIGPR6 [Mapview hg19]  GPR6 [Mapview hg38]
OMIM600553   
Gene and transcription
Genbank (Entrez)AK294648 AK295250 BC043414 BC117298 BC126301
RefSeq transcript (Entrez)NM_001286099 NM_005284
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPR6
Cluster EST : UnigeneHs.46332 [ NCBI ]
CGAP (NCI)Hs.46332
Alternative Splicing GalleryENSG00000146360
Gene ExpressionGPR6 [ NCBI-GEO ]   GPR6 [ EBI - ARRAY_EXPRESS ]   GPR6 [ SEEK ]   GPR6 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2830
GTEX Portal (Tissue expression)GPR6
Human Protein AtlasENSG00000146360-GPR6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP46095   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP46095  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP46095
Splice isoforms : SwissVarP46095
PhosPhoSitePlusP46095
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    GPR6    GPR_3/6/12_orphan   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)GPR6
DMDM Disease mutations2830
Blocks (Seattle)GPR6
SuperfamilyP46095
Human Protein Atlas [tissue]ENSG00000146360-GPR6 [tissue]
Peptide AtlasP46095
HPRD02775
IPIIPI00908743   IPI00004352   IPI00942047   
Protein Interaction databases
DIP (DOE-UCLA)P46095
IntAct (EBI)P46095
FunCoupENSG00000146360
BioGRIDGPR6
STRING (EMBL)GPR6
ZODIACGPR6
Ontologies - Pathways
QuickGOP46095
Ontology : AmiGO###############################################################################################################################################################################################################################################################            
Ontology : EGO-EBI###############################################################################################################################################################################################################################################################            
NDEx NetworkGPR6
Atlas of Cancer Signalling NetworkGPR6
Wikipedia pathwaysGPR6
Orthology - Evolution
OrthoDB2830
GeneTree (enSembl)ENSG00000146360
Phylogenetic Trees/Animal Genes : TreeFamGPR6
HOVERGENP46095
HOGENOMP46095
Homologs : HomoloGeneGPR6
Homology/Alignments : Family Browser (UCSC)GPR6
Gene fusions - Rearrangements
Fusion : QuiverGPR6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR6
dbVarGPR6
ClinVarGPR6
1000_GenomesGPR6 
Exome Variant ServerGPR6
ExAC (Exome Aggregation Consortium)ENSG00000146360
GNOMAD BrowserENSG00000146360
Varsome BrowserGPR6
Genetic variants : HAPMAP2830
Genomic Variants (DGV)GPR6 [DGVbeta]
DECIPHERGPR6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR6 
Mutations
ICGC Data PortalGPR6 
TCGA Data PortalGPR6 
Broad Tumor PortalGPR6
OASIS PortalGPR6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPR6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPR6
DgiDB (Drug Gene Interaction Database)GPR6
DoCM (Curated mutations)GPR6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPR6 (select a term)
intoGenGPR6
Cancer3DGPR6(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600553   
Orphanet
DisGeNETGPR6
MedgenGPR6
Genetic Testing Registry GPR6
NextProtP46095 [Medical]
TSGene2830
GENETestsGPR6
Target ValidationGPR6
Huge Navigator GPR6 [HugePedia]
snp3D : Map Gene to Disease2830
BioCentury BCIQGPR6
ClinGenGPR6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2830
Chemical/Pharm GKB GenePA28904
Clinical trialGPR6
Miscellaneous
canSAR (ICR)GPR6 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPR6
EVEXGPR6
GoPubMedGPR6
iHOPGPR6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 13:47:55 CEST 2018

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