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GPR65 (G protein-coupled receptor 65)

Identity

Alias_symbol (synonym)hTDAG8
TDAG8
Other alias
HGNC (Hugo) GPR65
LocusID (NCBI) 8477
Atlas_Id 45726
Location 14q31.3  [Link to chromosome band 14q31]
Location_base_pair Starts at 88005124 and ends at 88014811 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPR65   4517
Cards
Entrez_Gene (NCBI)GPR65  8477  G protein-coupled receptor 65
AliasesTDAG8; hTDAG8
GeneCards (Weizmann)GPR65
Ensembl hg19 (Hinxton)ENSG00000140030 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140030 [Gene_View]  chr14:88005124-88014811 [Contig_View]  GPR65 [Vega]
ICGC DataPortalENSG00000140030
TCGA cBioPortalGPR65
AceView (NCBI)GPR65
Genatlas (Paris)GPR65
WikiGenes8477
SOURCE (Princeton)GPR65
Genetics Home Reference (NIH)GPR65
Genomic and cartography
GoldenPath hg38 (UCSC)GPR65  -     chr14:88005124-88014811 +  14q31.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR65  -     14q31.3   [Description]    (hg19-Feb_2009)
EnsemblGPR65 - 14q31.3 [CytoView hg19]  GPR65 - 14q31.3 [CytoView hg38]
Mapping of homologs : NCBIGPR65 [Mapview hg19]  GPR65 [Mapview hg38]
OMIM604620   
Gene and transcription
Genbank (Entrez)AK313797 BC035633 BC071715 DQ890834 DQ893989
RefSeq transcript (Entrez)NM_003608
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPR65
Cluster EST : UnigeneHs.443243 [ NCBI ]
CGAP (NCI)Hs.443243
Alternative Splicing GalleryENSG00000140030
Gene ExpressionGPR65 [ NCBI-GEO ]   GPR65 [ EBI - ARRAY_EXPRESS ]   GPR65 [ SEEK ]   GPR65 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR65 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8477
GTEX Portal (Tissue expression)GPR65
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IYL9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IYL9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IYL9
Splice isoforms : SwissVarQ8IYL9
PhosPhoSitePlusQ8IYL9
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Psych_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)GPR65
DMDM Disease mutations8477
Blocks (Seattle)GPR65
SuperfamilyQ8IYL9
Human Protein AtlasENSG00000140030
Peptide AtlasQ8IYL9
HPRD07057
IPIIPI00337428   
Protein Interaction databases
DIP (DOE-UCLA)Q8IYL9
IntAct (EBI)Q8IYL9
FunCoupENSG00000140030
BioGRIDGPR65
STRING (EMBL)GPR65
ZODIACGPR65
Ontologies - Pathways
QuickGOQ8IYL9
Ontology : AmiGOG-protein coupled receptor activity  plasma membrane  plasma membrane  integral component of plasma membrane  apoptotic process  immune response  G-protein coupled receptor signaling pathway  multicellular organism development  response to acidic pH  positive regulation of cAMP biosynthetic process  actin cytoskeleton reorganization  positive regulation of Rho protein signal transduction  positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway  positive regulation of stress fiber assembly  activation of GTPase activity  
Ontology : EGO-EBIG-protein coupled receptor activity  plasma membrane  plasma membrane  integral component of plasma membrane  apoptotic process  immune response  G-protein coupled receptor signaling pathway  multicellular organism development  response to acidic pH  positive regulation of cAMP biosynthetic process  actin cytoskeleton reorganization  positive regulation of Rho protein signal transduction  positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway  positive regulation of stress fiber assembly  activation of GTPase activity  
NDEx NetworkGPR65
Atlas of Cancer Signalling NetworkGPR65
Wikipedia pathwaysGPR65
Orthology - Evolution
OrthoDB8477
GeneTree (enSembl)ENSG00000140030
Phylogenetic Trees/Animal Genes : TreeFamGPR65
HOVERGENQ8IYL9
HOGENOMQ8IYL9
Homologs : HomoloGeneGPR65
Homology/Alignments : Family Browser (UCSC)GPR65
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR65 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR65
dbVarGPR65
ClinVarGPR65
1000_GenomesGPR65 
Exome Variant ServerGPR65
ExAC (Exome Aggregation Consortium)GPR65 (select the gene name)
Genetic variants : HAPMAP8477
Genomic Variants (DGV)GPR65 [DGVbeta]
DECIPHERGPR65 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR65 
Mutations
ICGC Data PortalGPR65 
TCGA Data PortalGPR65 
Broad Tumor PortalGPR65
OASIS PortalGPR65 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR65  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPR65
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPR65
DgiDB (Drug Gene Interaction Database)GPR65
DoCM (Curated mutations)GPR65 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPR65 (select a term)
intoGenGPR65
Cancer3DGPR65(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604620   
Orphanet
MedgenGPR65
Genetic Testing Registry GPR65
NextProtQ8IYL9 [Medical]
TSGene8477
GENETestsGPR65
Target ValidationGPR65
Huge Navigator GPR65 [HugePedia]
snp3D : Map Gene to Disease8477
BioCentury BCIQGPR65
ClinGenGPR65
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8477
Chemical/Pharm GKB GenePA28909
Clinical trialGPR65
Miscellaneous
canSAR (ICR)GPR65 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPR65
EVEXGPR65
GoPubMedGPR65
iHOPGPR65
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:54:41 CEST 2017

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