Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8477
MIM: 604620
HGNC: 4517
Ensembl: ENSG00000140030
Variants:
dbSNP: 8477
ClinVar: 8477
TCGA: ENSG00000140030
COSMIC: GPR65
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000140030 | ENST00000267549 | Q8IYL9 |
| ENSG00000140030 | ENST00000267549 | B5B0C2 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38527054 | 2024 | The proton-sensing receptors TDAG8 and GPR4 are differentially expressed in human and mouse oligodendrocytes: Exploring their role in neuroinflammation and multiple sclerosis. | 0 |
| 38527054 | 2024 | The proton-sensing receptors TDAG8 and GPR4 are differentially expressed in human and mouse oligodendrocytes: Exploring their role in neuroinflammation and multiple sclerosis. | 0 |
| 37723567 | 2023 | GPR65 inhibits human trophoblast cell adhesion through upregulation of MYLK and downregulation of fibronectin via cAMP-ERK signaling in a low pH environment. | 1 |
| 37749885 | 2023 | Intestinal epithelial pH-sensing receptor GPR65 maintains mucosal homeostasis via regulating antimicrobial defense and restrains gut inflammation in inflammatory bowel disease. | 1 |
| 38001521 | 2023 | Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways. | 3 |
| 37723567 | 2023 | GPR65 inhibits human trophoblast cell adhesion through upregulation of MYLK and downregulation of fibronectin via cAMP-ERK signaling in a low pH environment. | 1 |
| 37749885 | 2023 | Intestinal epithelial pH-sensing receptor GPR65 maintains mucosal homeostasis via regulating antimicrobial defense and restrains gut inflammation in inflammatory bowel disease. | 1 |
| 38001521 | 2023 | Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways. | 3 |
| 34656742 | 2022 | Multilocus evaluation of genetic predictors of multiple sclerosis. | 1 |
| 35218908 | 2022 | IBD-associated G protein-coupled receptor 65 variant compromises signalling and impairs key functions involved in inflammation. | 4 |
| 35343079 | 2022 | GPR65 promotes intestinal mucosal Th1 and Th17 cell differentiation and gut inflammation through downregulating NUAK2. | 13 |
| 36102304 | 2022 | MicroRNAs combined with the TLR4/TDAG8 mRNAs and proinflammatory cytokines are biomarkers for the rapid diagnosis of sepsis. | 2 |
| 34656742 | 2022 | Multilocus evaluation of genetic predictors of multiple sclerosis. | 1 |
| 35218908 | 2022 | IBD-associated G protein-coupled receptor 65 variant compromises signalling and impairs key functions involved in inflammation. | 4 |
| 35343079 | 2022 | GPR65 promotes intestinal mucosal Th1 and Th17 cell differentiation and gut inflammation through downregulating NUAK2. | 13 |
Citation
Dessen P
GPR65 (G protein-coupled receptor 65)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45726/gpr65
