GPR87 (G protein-coupled receptor 87)

2007-02-01  

Identity

HGNC
GPR87
LOCATION
3q25.1
LOCUSID
53836
ALIAS
FKSG78,GPR95,KPG_002

Other Information

Locus ID:

NCBI: 53836
MIM: 606379
HGNC: 4538
Ensembl: ENSG00000138271

Variants:

dbSNP: 53836
ClinVar: 53836
TCGA: ENSG00000138271
COSMIC: GPR87

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138271ENST00000260843Q9BY21

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
179051982007The orphan GPCR GPR87 was deorphanized and shown to be a lysophosphatidic acid receptor.86
180575352008GPR87 is an overexpressed G-protein coupled receptor in squamous cell carcinoma of the lung.24
196025892009The G protein-coupled receptor 87 is necessary for p53-dependent cell survival in response to genotoxic stress.21
181835962008hGPR87 contributes to viability of human tumor cells.20
282886302017Overexpression of G protein-coupled receptor GPR87 promotes pancreatic cancer aggressiveness and activates NF-κB signaling pathway.14
235933892013G protein-coupled receptor 87 (GPR87) promotes the growth and metastasis of CD133⁺ cancer stem-like cells in hepatocellular carcinoma.13
264738542015G Protein-Coupled Receptor 87 (GPR87) Promotes Cell Proliferation in Human Bladder Cancer Cells.7
237522732013Expression and role of GPR87 in urothelial carcinoma of the bladder.5
278658732017Signaling via G proteins mediates tumorigenic effects of GPR87.3

Citation

Dessen P

GPR87 (G protein-coupled receptor 87)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/50035/gpr87