Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GPRC5B (G protein-coupled receptor class C group 5 member B)

Identity

Alias (NCBI)RAIG-2
RAIG2
HGNC (Hugo) GPRC5B
HGNC Alias symbRAIG-2
HGNC Previous nameG protein-coupled receptor, family C, group 1, member B
 G protein-coupled receptor, family C, group 5, member B
 G protein-coupled receptor, class C, group 5, member B
LocusID (NCBI) 51704
Atlas_Id 64017
Location 16p12.3  [Link to chromosome band 16p12]
Location_base_pair Starts at 19856691 and ends at 19884848 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GPRC5B (16p12.3) / GPRC5B (16p12.3)RBM12B (8q22.1) / GPRC5B (16p12.3)TNS4 (17q21.2) / GPRC5B (16p12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)GPRC5B   13308
Cards
Entrez_Gene (NCBI)GPRC5B    G protein-coupled receptor class C group 5 member B
AliasesRAIG-2; RAIG2
GeneCards (Weizmann)GPRC5B
Ensembl hg19 (Hinxton)ENSG00000167191 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167191 [Gene_View]  ENSG00000167191 [Sequence]  chr16:19856691-19884848 [Contig_View]  GPRC5B [Vega]
ICGC DataPortalENSG00000167191
TCGA cBioPortalGPRC5B
AceView (NCBI)GPRC5B
Genatlas (Paris)GPRC5B
SOURCE (Princeton)GPRC5B
Genetics Home Reference (NIH)GPRC5B
Genomic and cartography
GoldenPath hg38 (UCSC)GPRC5B  -     chr16:19856691-19884848 -  16p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPRC5B  -     16p12.3   [Description]    (hg19-Feb_2009)
GoldenPathGPRC5B - 16p12.3 [CytoView hg19]  GPRC5B - 16p12.3 [CytoView hg38]
ImmunoBaseENSG00000167191
Genome Data Viewer NCBIGPRC5B [Mapview hg19]  
OMIM605948   
Gene and transcription
Genbank (Entrez)AF181862 AF202640 AJ276101 AK075119 AK294680
RefSeq transcript (Entrez)NM_001304771 NM_016235
Consensus coding sequences : CCDS (NCBI)GPRC5B
Gene ExpressionGPRC5B [ NCBI-GEO ]   GPRC5B [ EBI - ARRAY_EXPRESS ]   GPRC5B [ SEEK ]   GPRC5B [ MEM ]
Gene Expression Viewer (FireBrowse)GPRC5B [ Firebrowse - Broad ]
GenevisibleExpression of GPRC5B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51704
GTEX Portal (Tissue expression)GPRC5B
Human Protein AtlasENSG00000167191-GPRC5B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZH0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZH0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZH0
PhosPhoSitePlusQ9NZH0
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F3_4 (PS50259)   
Domains : Interpro (EBI)GPCR_3_C   
Domain families : Pfam (Sanger)7tm_3 (PF00003)   
Domain families : Pfam (NCBI)pfam00003   
Conserved Domain (NCBI)GPRC5B
SuperfamilyQ9NZH0
AlphaFold pdb e-kbQ9NZH0   
Human Protein Atlas [tissue]ENSG00000167191-GPRC5B [tissue]
HPRD16177
Protein Interaction databases
DIP (DOE-UCLA)Q9NZH0
IntAct (EBI)Q9NZH0
BioGRIDGPRC5B
STRING (EMBL)GPRC5B
ZODIACGPRC5B
Ontologies - Pathways
QuickGOQ9NZH0
Ontology : AmiGOG protein-coupled receptor binding  G protein-coupled receptor activity  extracellular space  nucleoplasm  nucleolus  cytosol  plasma membrane  G protein-coupled receptor signaling pathway  cell surface  integral component of membrane  protein kinase binding  protein kinase binding  protein kinase activator activity  protein kinase activator activity  cytoplasmic vesicle membrane  activation of protein kinase activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  intracellular membrane-bounded organelle  intracellular membrane-bounded organelle  receptor complex  positive regulation of neuron differentiation  positive regulation of inflammatory response  positive regulation of macrophage cytokine production  positive regulation of protein tyrosine kinase activity  extracellular exosome  extracellular exosome  extracellular exosome  positive regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIG protein-coupled receptor binding  G protein-coupled receptor activity  extracellular space  nucleoplasm  nucleolus  cytosol  plasma membrane  G protein-coupled receptor signaling pathway  cell surface  integral component of membrane  protein kinase binding  protein kinase binding  protein kinase activator activity  protein kinase activator activity  cytoplasmic vesicle membrane  activation of protein kinase activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  intracellular membrane-bounded organelle  intracellular membrane-bounded organelle  receptor complex  positive regulation of neuron differentiation  positive regulation of inflammatory response  positive regulation of macrophage cytokine production  positive regulation of protein tyrosine kinase activity  extracellular exosome  extracellular exosome  extracellular exosome  positive regulation of canonical Wnt signaling pathway  
NDEx NetworkGPRC5B
Atlas of Cancer Signalling NetworkGPRC5B
Wikipedia pathwaysGPRC5B
Orthology - Evolution
OrthoDB51704
GeneTree (enSembl)ENSG00000167191
Phylogenetic Trees/Animal Genes : TreeFamGPRC5B
Homologs : HomoloGeneGPRC5B
Homology/Alignments : Family Browser (UCSC)GPRC5B
Gene fusions - Rearrangements
Fusion : QuiverGPRC5B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPRC5B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPRC5B
dbVarGPRC5B
ClinVarGPRC5B
MonarchGPRC5B
1000_GenomesGPRC5B 
Exome Variant ServerGPRC5B
GNOMAD BrowserENSG00000167191
Varsome BrowserGPRC5B
ACMGGPRC5B variants
VarityQ9NZH0
Genomic Variants (DGV)GPRC5B [DGVbeta]
DECIPHERGPRC5B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPRC5B 
Mutations
ICGC Data PortalGPRC5B 
TCGA Data PortalGPRC5B 
Broad Tumor PortalGPRC5B
OASIS PortalGPRC5B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPRC5B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGPRC5B
Mutations and Diseases : HGMDGPRC5B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGPRC5B
DgiDB (Drug Gene Interaction Database)GPRC5B
DoCM (Curated mutations)GPRC5B
CIViC (Clinical Interpretations of Variants in Cancer)GPRC5B
Cancer3DGPRC5B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605948   
Orphanet
DisGeNETGPRC5B
MedgenGPRC5B
Genetic Testing Registry GPRC5B
NextProtQ9NZH0 [Medical]
GENETestsGPRC5B
Target ValidationGPRC5B
Huge Navigator GPRC5B [HugePedia]
ClinGenGPRC5B
Clinical trials, drugs, therapy
MyCancerGenomeGPRC5B
Protein Interactions : CTDGPRC5B
Pharm GKB GenePA28938
PharosQ9NZH0
Clinical trialGPRC5B
Miscellaneous
canSAR (ICR)GPRC5B
HarmonizomeGPRC5B
DataMed IndexGPRC5B
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGPRC5B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:52:03 CEST 2021

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