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GPRC5B (G protein-coupled receptor class C group 5 member B)

Identity

Alias_namesG protein-coupled receptor, family C, group 1, member B
G protein-coupled receptor, family C, group 5, member B
G protein-coupled receptor, class C, group 5, member B
Alias_symbol (synonym)RAIG-2
Other aliasRAIG2
HGNC (Hugo) GPRC5B
LocusID (NCBI) 51704
Atlas_Id 64017
Location 16p12.3  [Link to chromosome band 16p12]
Location_base_pair Starts at 19858971 and ends at 19885634 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GPRC5B (16p12.3) / GPRC5B (16p12.3)RBM12B (8q22.1) / GPRC5B (16p12.3)TNS4 (17q21.2) / GPRC5B (16p12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPRC5B   13308
Cards
Entrez_Gene (NCBI)GPRC5B  51704  G protein-coupled receptor class C group 5 member B
AliasesRAIG-2; RAIG2
GeneCards (Weizmann)GPRC5B
Ensembl hg19 (Hinxton)ENSG00000167191 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167191 [Gene_View]  chr16:19858971-19885634 [Contig_View]  GPRC5B [Vega]
ICGC DataPortalENSG00000167191
TCGA cBioPortalGPRC5B
AceView (NCBI)GPRC5B
Genatlas (Paris)GPRC5B
WikiGenes51704
SOURCE (Princeton)GPRC5B
Genetics Home Reference (NIH)GPRC5B
Genomic and cartography
GoldenPath hg38 (UCSC)GPRC5B  -     chr16:19858971-19885634 -  16p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPRC5B  -     16p12.3   [Description]    (hg19-Feb_2009)
EnsemblGPRC5B - 16p12.3 [CytoView hg19]  GPRC5B - 16p12.3 [CytoView hg38]
Mapping of homologs : NCBIGPRC5B [Mapview hg19]  GPRC5B [Mapview hg38]
OMIM605948   
Gene and transcription
Genbank (Entrez)AF181862 AF202640 AJ276101 AK075119 AK294680
RefSeq transcript (Entrez)NM_001304771 NM_016235
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPRC5B
Cluster EST : UnigeneHs.148685 [ NCBI ]
CGAP (NCI)Hs.148685
Alternative Splicing GalleryENSG00000167191
Gene ExpressionGPRC5B [ NCBI-GEO ]   GPRC5B [ EBI - ARRAY_EXPRESS ]   GPRC5B [ SEEK ]   GPRC5B [ MEM ]
Gene Expression Viewer (FireBrowse)GPRC5B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51704
GTEX Portal (Tissue expression)GPRC5B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZH0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZH0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZH0
Splice isoforms : SwissVarQ9NZH0
PhosPhoSitePlusQ9NZH0
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F3_4 (PS50259)   
Domains : Interpro (EBI)GPCR_3_C   
Domain families : Pfam (Sanger)7tm_3 (PF00003)   
Domain families : Pfam (NCBI)pfam00003   
Conserved Domain (NCBI)GPRC5B
DMDM Disease mutations51704
Blocks (Seattle)GPRC5B
SuperfamilyQ9NZH0
Human Protein AtlasENSG00000167191
Peptide AtlasQ9NZH0
HPRD16177
IPIIPI01012002   IPI00008239   IPI01012082   IPI00922816   
Protein Interaction databases
DIP (DOE-UCLA)Q9NZH0
IntAct (EBI)Q9NZH0
FunCoupENSG00000167191
BioGRIDGPRC5B
STRING (EMBL)GPRC5B
ZODIACGPRC5B
Ontologies - Pathways
QuickGOQ9NZH0
Ontology : AmiGOG-protein coupled receptor binding  G-protein coupled receptor activity  extracellular space  nucleus  nucleolus  cytosol  plasma membrane  G-protein coupled receptor signaling pathway  locomotory behavior  cell surface  positive regulation of neuron projection development  integral component of membrane  protein kinase binding  protein kinase activator activity  cytoplasmic vesicle membrane  activation of protein kinase activity  glucose homeostasis  positive regulation of I-kappaB kinase/NF-kappaB signaling  intracellular membrane-bounded organelle  membrane raft  positive regulation of neuron differentiation  positive regulation of inflammatory response  positive regulation of macrophage cytokine production  positive regulation of protein tyrosine kinase activity  extracellular exosome  positive regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIG-protein coupled receptor binding  G-protein coupled receptor activity  extracellular space  nucleus  nucleolus  cytosol  plasma membrane  G-protein coupled receptor signaling pathway  locomotory behavior  cell surface  positive regulation of neuron projection development  integral component of membrane  protein kinase binding  protein kinase activator activity  cytoplasmic vesicle membrane  activation of protein kinase activity  glucose homeostasis  positive regulation of I-kappaB kinase/NF-kappaB signaling  intracellular membrane-bounded organelle  membrane raft  positive regulation of neuron differentiation  positive regulation of inflammatory response  positive regulation of macrophage cytokine production  positive regulation of protein tyrosine kinase activity  extracellular exosome  positive regulation of canonical Wnt signaling pathway  
NDEx NetworkGPRC5B
Atlas of Cancer Signalling NetworkGPRC5B
Wikipedia pathwaysGPRC5B
Orthology - Evolution
OrthoDB51704
GeneTree (enSembl)ENSG00000167191
Phylogenetic Trees/Animal Genes : TreeFamGPRC5B
HOVERGENQ9NZH0
HOGENOMQ9NZH0
Homologs : HomoloGeneGPRC5B
Homology/Alignments : Family Browser (UCSC)GPRC5B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPRC5B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPRC5B
dbVarGPRC5B
ClinVarGPRC5B
1000_GenomesGPRC5B 
Exome Variant ServerGPRC5B
ExAC (Exome Aggregation Consortium)GPRC5B (select the gene name)
Genetic variants : HAPMAP51704
Genomic Variants (DGV)GPRC5B [DGVbeta]
DECIPHERGPRC5B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPRC5B 
Mutations
ICGC Data PortalGPRC5B 
TCGA Data PortalGPRC5B 
Broad Tumor PortalGPRC5B
OASIS PortalGPRC5B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPRC5B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPRC5B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPRC5B
DgiDB (Drug Gene Interaction Database)GPRC5B
DoCM (Curated mutations)GPRC5B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPRC5B (select a term)
intoGenGPRC5B
Cancer3DGPRC5B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605948   
Orphanet
MedgenGPRC5B
Genetic Testing Registry GPRC5B
NextProtQ9NZH0 [Medical]
TSGene51704
GENETestsGPRC5B
Target ValidationGPRC5B
Huge Navigator GPRC5B [HugePedia]
snp3D : Map Gene to Disease51704
BioCentury BCIQGPRC5B
ClinGenGPRC5B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51704
Chemical/Pharm GKB GenePA28938
Clinical trialGPRC5B
Miscellaneous
canSAR (ICR)GPRC5B (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPRC5B
EVEXGPRC5B
GoPubMedGPRC5B
iHOPGPRC5B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 15:51:21 CEST 2017

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