Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GPRC6A (G protein-coupled receptor class C group 6 member A)

Identity

Alias_namesG protein-coupled receptor, family C, group 6, member A
G protein-coupled receptor, class C, group 6, member A
Alias_symbol (synonym)bA86F4.3
Other aliasGPCR
HGNC (Hugo) GPRC6A
LocusID (NCBI) 222545
Atlas_Id 52630
Location 6q22.1  [Link to chromosome band 6q22]
Location_base_pair Starts at 116792085 and ends at 116829057 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPRC6A   18510
Cards
Entrez_Gene (NCBI)GPRC6A  222545  G protein-coupled receptor class C group 6 member A
AliasesGPCR; bA86F4.3
GeneCards (Weizmann)GPRC6A
Ensembl hg19 (Hinxton)ENSG00000173612 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173612 [Gene_View]  ENSG00000173612 [Sequence]  chr6:116792085-116829057 [Contig_View]  GPRC6A [Vega]
ICGC DataPortalENSG00000173612
TCGA cBioPortalGPRC6A
AceView (NCBI)GPRC6A
Genatlas (Paris)GPRC6A
WikiGenes222545
SOURCE (Princeton)GPRC6A
Genetics Home Reference (NIH)GPRC6A
Genomic and cartography
GoldenPath hg38 (UCSC)GPRC6A  -     chr6:116792085-116829057 -  6q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPRC6A  -     6q22.1   [Description]    (hg19-Feb_2009)
EnsemblGPRC6A - 6q22.1 [CytoView hg19]  GPRC6A - 6q22.1 [CytoView hg38]
Mapping of homologs : NCBIGPRC6A [Mapview hg19]  GPRC6A [Mapview hg38]
OMIM613572   
Gene and transcription
Genbank (Entrez)AF502962 AW771483 AY435125 AY435126 AY435127
RefSeq transcript (Entrez)NM_001286354 NM_001286355 NM_148963
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPRC6A
Cluster EST : UnigeneHs.266745 [ NCBI ]
CGAP (NCI)Hs.266745
Alternative Splicing GalleryENSG00000173612
Gene ExpressionGPRC6A [ NCBI-GEO ]   GPRC6A [ EBI - ARRAY_EXPRESS ]   GPRC6A [ SEEK ]   GPRC6A [ MEM ]
Gene Expression Viewer (FireBrowse)GPRC6A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)222545
GTEX Portal (Tissue expression)GPRC6A
Human Protein AtlasENSG00000173612-GPRC6A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T6X5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T6X5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T6X5
Splice isoforms : SwissVarQ5T6X5
PhosPhoSitePlusQ5T6X5
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F3_2 (PS00980)    G_PROTEIN_RECEP_F3_4 (PS50259)   
Domains : Interpro (EBI)ANF_lig-bd_rcpt    GPCR_3    GPCR_3_9-Cys_dom    GPCR_3_9-Cys_sf    GPCR_3_C    GPCR_3_CS    Peripla_BP_I   
Domain families : Pfam (Sanger)7tm_3 (PF00003)    ANF_receptor (PF01094)    NCD3G (PF07562)   
Domain families : Pfam (NCBI)pfam00003    pfam01094    pfam07562   
Conserved Domain (NCBI)GPRC6A
DMDM Disease mutations222545
Blocks (Seattle)GPRC6A
SuperfamilyQ5T6X5
Human Protein Atlas [tissue]ENSG00000173612-GPRC6A [tissue]
Peptide AtlasQ5T6X5
HPRD17074
IPIIPI00169389   IPI00656032   IPI00426401   
Protein Interaction databases
DIP (DOE-UCLA)Q5T6X5
IntAct (EBI)Q5T6X5
FunCoupENSG00000173612
BioGRIDGPRC6A
STRING (EMBL)GPRC6A
ZODIACGPRC6A
Ontologies - Pathways
QuickGOQ5T6X5
Ontology : AmiGOG protein-coupled receptor activity  intracellular  plasma membrane  integral component of plasma membrane  G protein-coupled receptor signaling pathway  cell surface  calcium-mediated signaling  response to amino acid  response to amino acid  
Ontology : EGO-EBIG protein-coupled receptor activity  intracellular  plasma membrane  integral component of plasma membrane  G protein-coupled receptor signaling pathway  cell surface  calcium-mediated signaling  response to amino acid  response to amino acid  
NDEx NetworkGPRC6A
Atlas of Cancer Signalling NetworkGPRC6A
Wikipedia pathwaysGPRC6A
Orthology - Evolution
OrthoDB222545
GeneTree (enSembl)ENSG00000173612
Phylogenetic Trees/Animal Genes : TreeFamGPRC6A
HOVERGENQ5T6X5
HOGENOMQ5T6X5
Homologs : HomoloGeneGPRC6A
Homology/Alignments : Family Browser (UCSC)GPRC6A
Gene fusions - Rearrangements
Fusion : QuiverGPRC6A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPRC6A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPRC6A
dbVarGPRC6A
ClinVarGPRC6A
1000_GenomesGPRC6A 
Exome Variant ServerGPRC6A
ExAC (Exome Aggregation Consortium)ENSG00000173612
GNOMAD BrowserENSG00000173612
Varsome BrowserGPRC6A
Genetic variants : HAPMAP222545
Genomic Variants (DGV)GPRC6A [DGVbeta]
DECIPHERGPRC6A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPRC6A 
Mutations
ICGC Data PortalGPRC6A 
TCGA Data PortalGPRC6A 
Broad Tumor PortalGPRC6A
OASIS PortalGPRC6A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPRC6A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPRC6A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPRC6A
DgiDB (Drug Gene Interaction Database)GPRC6A
DoCM (Curated mutations)GPRC6A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPRC6A (select a term)
intoGenGPRC6A
Cancer3DGPRC6A(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613572   
Orphanet
DisGeNETGPRC6A
MedgenGPRC6A
Genetic Testing Registry GPRC6A
NextProtQ5T6X5 [Medical]
TSGene222545
GENETestsGPRC6A
Target ValidationGPRC6A
Huge Navigator GPRC6A [HugePedia]
snp3D : Map Gene to Disease222545
BioCentury BCIQGPRC6A
ClinGenGPRC6A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD222545
Chemical/Pharm GKB GenePA38342
Clinical trialGPRC6A
Miscellaneous
canSAR (ICR)GPRC6A (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPRC6A
EVEXGPRC6A
GoPubMedGPRC6A
iHOPGPRC6A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:09:26 CET 2018

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