Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GPT (glutamic-pyruvate transaminase (alanine aminotransferase))

Identity

Alias_namesglutamic-pyruvate transaminase (alanine aminotransferase)
Alias_symbol (synonym)ALT1
GPT1
Other aliasAAT1
HGNC (Hugo) GPT
LocusID (NCBI) 2875
Atlas_Id 49867
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 145729465 and ends at 145732555 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Liver: Fibrolamellar carcinoma


External links

Nomenclature
HGNC (Hugo)GPT   4552
Cards
Entrez_Gene (NCBI)GPT  2875  glutamic-pyruvate transaminase (alanine aminotransferase)
AliasesAAT1; ALT1; GPT1
GeneCards (Weizmann)GPT
Ensembl hg19 (Hinxton)ENSG00000167701 [Gene_View]  chr8:145729465-145732555 [Contig_View]  GPT [Vega]
Ensembl hg38 (Hinxton)ENSG00000167701 [Gene_View]  chr8:145729465-145732555 [Contig_View]  GPT [Vega]
ICGC DataPortalENSG00000167701
TCGA cBioPortalGPT
AceView (NCBI)GPT
Genatlas (Paris)GPT
WikiGenes2875
SOURCE (Princeton)GPT
Genetics Home Reference (NIH)GPT
Genomic and cartography
GoldenPath hg19 (UCSC)GPT  -     chr8:145729465-145732555 +  8q24.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GPT  -     8q24.3   [Description]    (hg38-Dec_2013)
EnsemblGPT - 8q24.3 [CytoView hg19]  GPT - 8q24.3 [CytoView hg38]
Mapping of homologs : NCBIGPT [Mapview hg19]  GPT [Mapview hg38]
OMIM138200   
Gene and transcription
Genbank (Entrez)AI283141 AK225562 AK298488 AK303779 BC018207
RefSeq transcript (Entrez)NM_005309
RefSeq genomic (Entrez)NC_000008 NC_018919 NG_015828 NT_008046 NW_004929341
Consensus coding sequences : CCDS (NCBI)GPT
Cluster EST : UnigeneHs.103502 [ NCBI ]
CGAP (NCI)Hs.103502
Alternative Splicing GalleryENSG00000167701
Gene ExpressionGPT [ NCBI-GEO ]   GPT [ EBI - ARRAY_EXPRESS ]   GPT [ SEEK ]   GPT [ MEM ]
Gene Expression Viewer (FireBrowse)GPT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2875
GTEX Portal (Tissue expression)GPT
Protein : pattern, domain, 3D structure
UniProt/SwissProtP24298   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP24298  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP24298
Splice isoforms : SwissVarP24298
Catalytic activity : Enzyme2.6.1.2 [ Enzyme-Expasy ]   2.6.1.22.6.1.2 [ IntEnz-EBI ]   2.6.1.2 [ BRENDA ]   2.6.1.2 [ KEGG ]   
PhosPhoSitePlusP24298
Domains : Interpro (EBI)Aminotransferase_I/II    PyrdxlP-dep_Trfase    PyrdxlP-dep_Trfase_major_sub1    PyrdxlP-dep_Trfase_major_sub2   
Domain families : Pfam (Sanger)Aminotran_1_2 (PF00155)   
Domain families : Pfam (NCBI)pfam00155   
Conserved Domain (NCBI)GPT
DMDM Disease mutations2875
Blocks (Seattle)GPT
SuperfamilyP24298
Human Protein AtlasENSG00000167701
Peptide AtlasP24298
HPRD00689
IPIIPI00217458   IPI00909969   
Protein Interaction databases
DIP (DOE-UCLA)P24298
IntAct (EBI)P24298
FunCoupENSG00000167701
BioGRIDGPT
STRING (EMBL)GPT
ZODIACGPT
Ontologies - Pathways
QuickGOP24298
Ontology : AmiGOL-alanine:2-oxoglutarate aminotransferase activity  L-alanine:2-oxoglutarate aminotransferase activity  extracellular space  cytosol  cellular amino acid biosynthetic process  pyridoxal phosphate binding  L-alanine catabolic process  extracellular exosome  
Ontology : EGO-EBIL-alanine:2-oxoglutarate aminotransferase activity  L-alanine:2-oxoglutarate aminotransferase activity  extracellular space  cytosol  cellular amino acid biosynthetic process  pyridoxal phosphate binding  L-alanine catabolic process  extracellular exosome  
Pathways : BIOCARTASARS Coronavirus Protease [Genes]   
Pathways : KEGGAlanine, aspartate and glutamate metabolism   
NDEx NetworkGPT
Atlas of Cancer Signalling NetworkGPT
Wikipedia pathwaysGPT
Orthology - Evolution
OrthoDB2875
GeneTree (enSembl)ENSG00000167701
Phylogenetic Trees/Animal Genes : TreeFamGPT
HOVERGENP24298
HOGENOMP24298
Homologs : HomoloGeneGPT
Homology/Alignments : Family Browser (UCSC)GPT
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPT
dbVarGPT
ClinVarGPT
1000_GenomesGPT 
Exome Variant ServerGPT
ExAC (Exome Aggregation Consortium)GPT (select the gene name)
Genetic variants : HAPMAP2875
Genomic Variants (DGV)GPT [DGVbeta]
DECIPHER (Syndromes)8:145729465-145732555  ENSG00000167701
CONAN: Copy Number AnalysisGPT 
Mutations
ICGC Data PortalGPT 
TCGA Data PortalGPT 
Broad Tumor PortalGPT
OASIS PortalGPT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPT  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPT
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPT
DgiDB (Drug Gene Interaction Database)GPT
DoCM (Curated mutations)GPT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPT (select a term)
intoGenGPT
Cancer3DGPT(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM138200   
Orphanet
MedgenGPT
Genetic Testing Registry GPT
NextProtP24298 [Medical]
TSGene2875
GENETestsGPT
Huge Navigator GPT [HugePedia]
snp3D : Map Gene to Disease2875
BioCentury BCIQGPT
ClinGenGPT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2875
Chemical/Pharm GKB GenePA28947
Clinical trialGPT
Miscellaneous
canSAR (ICR)GPT (select the gene name)
Probes
Litterature
PubMed107 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPT
EVEXGPT
GoPubMedGPT
iHOPGPT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:02:58 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.