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GPT (glutamic-pyruvate transaminase (alanine aminotransferase))

Identity

Other namesAAT1
ALT1
GPT1
HGNC (Hugo) GPT
LocusID (NCBI) 2875
Location 8q24.3
Location_base_pair Starts at 145729465 and ends at 145732555 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GPT   4552
Entrez_Gene (NCBI)GPT  2875  glutamic-pyruvate transaminase (alanine aminotransferase)
Cards
GeneCards (Weizmann)GPT
Ensembl (Hinxton)ENSG00000167701 [Gene_View]  chr8:145729465-145732555 [Contig_View]  GPT [Vega]
AceView (NCBI)GPT
Genatlas (Paris)GPT
SOURCE (Stanford)NM_005309
Genomic and cartography
GoldenPath (UCSC)GPT  -  8q24.3   chr8:145729465-145732555 +  8q24.3   [Description]    (hg19-Feb_2009)
EnsemblGPT - 8q24.3 [CytoView]
Mapping of homologs : NCBIGPT [Mapview]
OMIM138200   
Gene and transcription
Genbank (Entrez)AI283141 AK225562 AK298488 AK303779 BC018207
RefSeq transcript (SRS)NM_005309
RefSeq transcript (Entrez)NM_005309
RefSeq genomic (SRS)AC_000140 NC_000008 NC_018919 NG_015828 NT_037704 NW_001839142 NW_004078037
RefSeq genomic (Entrez)AC_000140 NC_000008 NC_018919 NG_015828 NT_037704 NW_001839142 NW_004078037
Consensus coding sequences : CCDS (NCBI)GPT
Cluster EST : UnigeneHs.103502 [ SRS ] Hs.103502 [ NCBI ]
CGAP (NCI)Hs.103502
Alternative Splicing : Fast-db (Paris)GSHG0029330
Alternative Splicing GalleryENSG00000167701
Gene ExpressionGPT [ NCBI-GEO ]   GPT [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP24298 (SRS) P24298 (Uniprot)
NextProtP24298
With graphics : InterProP24298
Splice isoforms : SwissVarP24298(Swissvar)
Domains : Interpro (SRS)Aminotransferase_I/II    PyrdxlP-dep_Trfase_major_dom    PyrdxlP-dep_Trfase_major_sub1    PyrdxlP-dep_Trfase_major_sub2   
Domains : Interpro (EBI)Aminotransferase_I/II    PyrdxlP-dep_Trfase_major_dom    PyrdxlP-dep_Trfase_major_sub1    PyrdxlP-dep_Trfase_major_sub2   
Related proteins : CluSTrP24298
Domain families : Pfam (SRS)Aminotran_1_2 (PF00155)   
Domain families : Pfam (Sanger)Aminotran_1_2 (PF00155)   
Domain families : Pfam (NCBI)pfam00155   
DMDM2875
Blocks (Seattle)P24298
Human Protein AtlasENSG00000167701
HPRD00689
IPIIPI00217458   IPI00909969   
Protein Interaction databases
DIP (DOE-UCLA)P24298
IntAct (EBI)P24298
FunCoupENSG00000167701
REACTOMEGPT
Protein Interaction Database2875
BioGRIDGPT
InParanoidP24298
Interologous Interaction database P24298
IntegromeDBGPT
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GPT
SNP (GeneSNP Utah)GPT
SNP : HGBaseGPT
Genetic variants : HAPMAPGPT
Somatic Mutations in Cancer : COSMICGPT 
CONAN: Copy Number AnalysisGPT 
Mutations and Diseases : HGMDGPT
OMIM138200   
GENETests138200   
Disease Genetic AssociationGPT
Huge Navigator GPT [HugePedia]  GPT [HugeCancerGEM]
Genomic VariantsGPT  GPT [DGVbeta]
snp3D : Map Gene to Disease2875
General knowledge
Homologs : HomoloGeneGPT
Homology/Alignments : Family Browser (UCSC)GPT
Phylogenetic Trees/Animal Genes : TreeFamGPT
Catalytic activity : Enzyme2.6.1.2 [ Enzyme-Expasy ]   2.6.1.2 [ Enzyme-SRS ]   2.6.1.2 [ IntEnz-EBI ]   2.6.1.2 [ BRENDA ]   2.6.1.2 [ KEGG ]   
Chemical/Protein Interactions : CTD2875
Chemical/Pharm GKB GenePA28947
Clinical trialGPT
Cancer Resource (Charite)ENSG00000167701
Ontology : AmiGOL-alanine:2-oxoglutarate aminotransferase activity  L-alanine:2-oxoglutarate aminotransferase activity  cytoplasm  cytosol  gluconeogenesis  nitrogen compound metabolic process  cellular amino acid biosynthetic process  pyridoxal phosphate binding  cellular nitrogen compound metabolic process  L-alanine catabolic process  small molecule metabolic process  
Ontology : EGO-EBIL-alanine:2-oxoglutarate aminotransferase activity  L-alanine:2-oxoglutarate aminotransferase activity  cytoplasm  cytosol  gluconeogenesis  nitrogen compound metabolic process  cellular amino acid biosynthetic process  pyridoxal phosphate binding  cellular nitrogen compound metabolic process  L-alanine catabolic process  small molecule metabolic process  
Pathways : BIOCARTASARS Coronavirus Protease [Genes]   
Pathways : KEGGCarbon fixationAlanine and aspartate metabolismGlutamate metabolism
Other databases
Probes
Litterature
PubMed74 Pubmed reference(s) in Entrez
PubGeneGPT
iHOPGPT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:24:13 CEST 2013
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