Atlas of Genetics and Cytogenetics in Oncology and Haematology

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GPX2 (glutathione peroxidase 2 (gastrointestinal))

Identity

Other namesGI-GPx
GPRP
GPRP-2
GPx-2
GPx-GI
GSHPX-GI
GSHPx-2
HGNC (Hugo) GPX2
LocusID (NCBI) 2877
Location 14q23.3
Location_base_pair Starts at 65405870 and ends at 65409623 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GPX2   4554
Entrez_Gene (NCBI)GPX2  2877  glutathione peroxidase 2 (gastrointestinal)
Cards
GeneCards (Weizmann)GPX2
Ensembl (Hinxton)ENSG00000176153 [Gene_View]  chr14:65405870-65409623 [Contig_View]  GPX2 [Vega]
AceView (NCBI)GPX2
Genatlas (Paris)GPX2
SOURCE (Stanford)NM_002083
Genomic and cartography
GoldenPath (UCSC)GPX2  -  14q23.3   chr14:65405870-65409623 -  14q23.3   [Description]    (hg19-Feb_2009)
EnsemblGPX2 - 14q23.3 [CytoView]
Mapping of homologs : NCBIGPX2 [Mapview]
OMIM138319   
Gene and transcription
Genbank (Entrez)AK225871 BC005277 BC016756 BC022820 BC039850
RefSeq transcript (SRS)NM_002083
RefSeq transcript (Entrez)NM_002083
RefSeq genomic (SRS)AC_000146 NC_000014 NC_018925 NT_026437 NW_001838111 NW_004078079
RefSeq genomic (Entrez)AC_000146 NC_000014 NC_018925 NT_026437 NW_001838111 NW_004078079
Consensus coding sequences : CCDS (NCBI)GPX2
Cluster EST : UnigeneHs.2704 [ SRS ] Hs.2704 [ NCBI ]
CGAP (NCI)Hs.2704
Alternative Splicing : Fast-db (Paris)GSHG0009426
Alternative Splicing GalleryENSG00000176153
Gene ExpressionGPX2 [ NCBI-GEO ]   GPX2 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP18283 (SRS) P18283 (Uniprot)
NextProtP18283
With graphics : InterProP18283
Splice isoforms : SwissVarP18283(Swissvar)
Domaine pattern : Prosite (SRS)GLUTATHIONE_PEROXID_1 (PS00460)    GLUTATHIONE_PEROXID_2 (PS00763)    GLUTATHIONE_PEROXID_3 (PS51355)   
Domaine pattern : Prosite (Expaxy)GLUTATHIONE_PEROXID_1 (PS00460)    GLUTATHIONE_PEROXID_2 (PS00763)    GLUTATHIONE_PEROXID_3 (PS51355)   
Domains : Interpro (SRS)Glutathione_peroxidase    Thioredoxin-like_fold   
Domains : Interpro (EBI)Glutathione_peroxidase    Thioredoxin-like_fold   
Related proteins : CluSTrP18283
Domain families : Pfam (SRS)GSHPx (PF00255)   
Domain families : Pfam (Sanger)GSHPx (PF00255)   
Domain families : Pfam (NCBI)pfam00255   
DMDM2877
Blocks (Seattle)P18283
PDB (SRS)2HE3   
PDB (PDBSum)2HE3   
PDB (IMB)2HE3   
PDB (RSDB)2HE3   
Human Protein AtlasENSG00000176153
HPRD11818
IPIIPI00298176   IPI01024786   IPI01025107   IPI01025563   
Protein Interaction databases
DIP (DOE-UCLA)P18283
IntAct (EBI)P18283
FunCoupENSG00000176153
REACTOMEGPX2
Protein Interaction Database2877
BioGRIDGPX2
InParanoidP18283
Interologous Interaction database P18283
IntegromeDBGPX2
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GPX2
SNP (GeneSNP Utah)GPX2
SNP : HGBaseGPX2
Genetic variants : HAPMAPGPX2
Somatic Mutations in Cancer : COSMICGPX2 
CONAN: Copy Number AnalysisGPX2 
Mutations and Diseases : HGMDGPX2
OMIM138319   
GENETests138319   
Disease Genetic AssociationGPX2
Huge Navigator GPX2 [HugePedia]  GPX2 [HugeCancerGEM]
Genomic VariantsGPX2  GPX2 [DGVbeta]
ClinVarGPX2
snp3D : Map Gene to Disease2877
General knowledge
Homologs : HomoloGeneGPX2
Homology/Alignments : Family Browser (UCSC)GPX2
Phylogenetic Trees/Animal Genes : TreeFamGPX2
Catalytic activity : Enzyme1.11.1.9 [ Enzyme-Expasy ]   1.11.1.9 [ Enzyme-SRS ]   1.11.1.9 [ IntEnz-EBI ]   1.11.1.9 [ BRENDA ]   1.11.1.9 [ KEGG ]   
Chemical/Protein Interactions : CTD2877
Chemical/Pharm GKB GenePA28950
Clinical trialGPX2
Cancer Resource (Charite)ENSG00000176153
Ontology : AmiGOtemperature homeostasis  negative regulation of inflammatory response to antigenic stimulus  glutathione peroxidase activity  nucleus  nucleolus  cytoplasm  response to oxidative stress  electron carrier activity  response to symbiotic bacterium  interaction with symbiont  
Ontology : EGO-EBItemperature homeostasis  negative regulation of inflammatory response to antigenic stimulus  glutathione peroxidase activity  nucleus  nucleolus  cytoplasm  response to oxidative stress  electron carrier activity  response to symbiotic bacterium  interaction with symbiont  
Pathways : KEGGGlutathione metabolismArachidonic acid metabolism
Other databases
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
PubGeneGPX2
iHOPGPX2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:58:54 CEST 2013
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