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GPX7 (glutathione peroxidase 7)

Identity

Other namesCL683
GPX6
GPx-7
GSHPx-7
NPGPx
HGNC (Hugo) GPX7
LocusID (NCBI) 2882
Location 1p32.3
Location_base_pair Starts at 53068043 and ends at 53074723 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GPX7   4559
Cards
Entrez_Gene (NCBI)GPX7  2882  glutathione peroxidase 7
GeneCards (Weizmann)GPX7
Ensembl (Hinxton)ENSG00000116157 [Gene_View]  chr1:53068043-53074723 [Contig_View]  GPX7 [Vega]
ICGC DataPortalENSG00000116157
cBioPortalGPX7
AceView (NCBI)GPX7
Genatlas (Paris)GPX7
WikiGenes2882
SOURCE (Princeton)NM_015696
Genomic and cartography
GoldenPath (UCSC)GPX7  -  1p32.3   chr1:53068043-53074723 +  1p32.3   [Description]    (hg19-Feb_2009)
EnsemblGPX7 - 1p32.3 [CytoView]
Mapping of homologs : NCBIGPX7 [Mapview]
OMIM615784   
Gene and transcription
Genbank (Entrez)AF091092 AF320068 AK027683 AY358402 BC032788
RefSeq transcript (Entrez)NM_015696
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NT_032977 NW_001838579 NW_004929290
Consensus coding sequences : CCDS (NCBI)GPX7
Cluster EST : UnigeneHs.43728 [ NCBI ]
CGAP (NCI)Hs.43728
Alternative Splicing : Fast-db (Paris)GSHG0000513
Alternative Splicing GalleryENSG00000116157
Gene ExpressionGPX7 [ NCBI-GEO ]     GPX7 [ SEEK ]   GPX7 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96SL4 (Uniprot)
NextProtQ96SL4  [Medical]
With graphics : InterProQ96SL4
Splice isoforms : SwissVarQ96SL4 (Swissvar)
Catalytic activity : Enzyme1.11.1.9 [ Enzyme-Expasy ]   1.11.1.91.11.1.9 [ IntEnz-EBI ]   1.11.1.9 [ BRENDA ]   1.11.1.9 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)GLUTATHIONE_PEROXID_1 (PS00460)    GLUTATHIONE_PEROXID_2 (PS00763)    GLUTATHIONE_PEROXID_3 (PS51355)   
Domains : Interpro (EBI)Glut_perox_Gpx7 [organisation]   Glutathione_peroxidase [organisation]   Thioredoxin-like_fold [organisation]  
Related proteins : CluSTrQ96SL4
Domain families : Pfam (Sanger)GSHPx (PF00255)   
Domain families : Pfam (NCBI)pfam00255   
DMDM Disease mutations2882
Blocks (Seattle)Q96SL4
PDB (SRS)2P31   
PDB (PDBSum)2P31   
PDB (IMB)2P31   
PDB (RSDB)2P31   
Human Protein AtlasENSG00000116157 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ96SL4
HPRD13606
IPIIPI00045798   
Protein Interaction databases
DIP (DOE-UCLA)Q96SL4
IntAct (EBI)Q96SL4
FunCoupENSG00000116157
BioGRIDGPX7
InParanoidQ96SL4
Interologous Interaction database Q96SL4
IntegromeDBGPX7
STRING (EMBL)GPX7
Ontologies - Pathways
Ontology : AmiGOperoxidase activity  glutathione peroxidase activity  extracellular region  endoplasmic reticulum  endoplasmic reticulum lumen  response to oxidative stress  oxidation-reduction process  
Ontology : EGO-EBIperoxidase activity  glutathione peroxidase activity  extracellular region  endoplasmic reticulum  endoplasmic reticulum lumen  response to oxidative stress  oxidation-reduction process  
Pathways : KEGGGlutathione metabolism    Arachidonic acid metabolism    Thyroid hormone synthesis   
Protein Interaction DatabaseGPX7
Wikipedia pathwaysGPX7
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GPX7
snp3D : Map Gene to Disease2882
SNP (GeneSNP Utah)GPX7
SNP : HGBaseGPX7
Genetic variants : HAPMAPGPX7
Exome VariantGPX7
1000_GenomesGPX7 
ICGC programENSG00000116157 
Somatic Mutations in Cancer : COSMICGPX7 
CONAN: Copy Number AnalysisGPX7 
Mutations and Diseases : HGMDGPX7
Mutations and Diseases : intOGenGPX7
Genomic VariantsGPX7  GPX7 [DGVbeta]
dbVarGPX7
ClinVarGPX7
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM615784   
MedgenGPX7
GENETestsGPX7
Disease Genetic AssociationGPX7
Huge Navigator GPX7 [HugePedia]  GPX7 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneGPX7
Homology/Alignments : Family Browser (UCSC)GPX7
Phylogenetic Trees/Animal Genes : TreeFamGPX7
Chemical/Protein Interactions : CTD2882
Chemical/Pharm GKB GenePA28955
Clinical trialGPX7
Cancer Resource (Charite)ENSG00000116157
Other databases
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
CoreMineGPX7
iHOPGPX7
OncoSearchGPX7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:48:39 CEST 2014

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