Atlas of Genetics and Cytogenetics in Oncology and Haematology


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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret jlhuret@AtlasGeneticsOncology.org
Donations are also welcome
If each casual visitor gives 3 Euros or Dollars, the Atlas is saved in a week !
If each professional gives 100 Euros or Dollars once a year (now), the Atlas is saved in 2 weeks !
Don't let the Atlas imminent demise
Note: we send fiscal receipts for donations equal or above 50 Euros or Dollars

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GPX7 (glutathione peroxidase 7)

Identity

Other namesCL683
GPX6
GPx-7
GSHPx-7
NPGPx
HGNC (Hugo) GPX7
LocusID (NCBI) 2882
Location 1p32.3
Location_base_pair Starts at 53068043 and ends at 53074723 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GPX7   4559
Cards
Entrez_Gene (NCBI)GPX7  2882  glutathione peroxidase 7
GeneCards (Weizmann)GPX7
Ensembl hg19 (Hinxton)ENSG00000116157 [Gene_View]  chr1:53068043-53074723 [Contig_View]  GPX7 [Vega]
Ensembl hg38 (Hinxton)ENSG00000116157 [Gene_View]  chr1:53068043-53074723 [Contig_View]  GPX7 [Vega]
ICGC DataPortalENSG00000116157
cBioPortalGPX7
AceView (NCBI)GPX7
Genatlas (Paris)GPX7
WikiGenes2882
SOURCE (Princeton)GPX7
Genomic and cartography
GoldenPath hg19 (UCSC)GPX7  -     chr1:53068043-53074723 +  1p32.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GPX7  -     1p32.3   [Description]    (hg38-Dec_2013)
EnsemblGPX7 - 1p32.3 [CytoView hg19]  GPX7 - 1p32.3 [CytoView hg38]
Mapping of homologs : NCBIGPX7 [Mapview hg19]  GPX7 [Mapview hg38]
OMIM615784   
Gene and transcription
Genbank (Entrez)AF091092 AF320068 AK027683 AY358402 BC032788
RefSeq transcript (Entrez)NM_015696
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929290
Consensus coding sequences : CCDS (NCBI)GPX7
Cluster EST : UnigeneHs.43728 [ NCBI ]
CGAP (NCI)Hs.43728
Alternative Splicing : Fast-db (Paris)GSHG0000513
Alternative Splicing GalleryENSG00000116157
Gene ExpressionGPX7 [ NCBI-GEO ]     GPX7 [ SEEK ]   GPX7 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96SL4 (Uniprot)
NextProtQ96SL4  [Medical]
With graphics : InterProQ96SL4
Splice isoforms : SwissVarQ96SL4 (Swissvar)
Catalytic activity : Enzyme1.11.1.9 [ Enzyme-Expasy ]   1.11.1.91.11.1.9 [ IntEnz-EBI ]   1.11.1.9 [ BRENDA ]   1.11.1.9 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)GLUTATHIONE_PEROXID_1 (PS00460)    GLUTATHIONE_PEROXID_2 (PS00763)    GLUTATHIONE_PEROXID_3 (PS51355)   
Domains : Interpro (EBI)Glut_perox_Gpx7    Glutathione_peroxidase    GPX_AS    GPX_CS    Thioredoxin-like_fold   
Related proteins : CluSTrQ96SL4
Domain families : Pfam (Sanger)GSHPx (PF00255)   
Domain families : Pfam (NCBI)pfam00255   
DMDM Disease mutations2882
Blocks (Seattle)Q96SL4
PDB (SRS)2P31   
PDB (PDBSum)2P31   
PDB (IMB)2P31   
PDB (RSDB)2P31   
Human Protein AtlasENSG00000116157
Peptide AtlasQ96SL4
HPRD13606
IPIIPI00045798   
Protein Interaction databases
DIP (DOE-UCLA)Q96SL4
IntAct (EBI)Q96SL4
FunCoupENSG00000116157
BioGRIDGPX7
IntegromeDBGPX7
STRING (EMBL)GPX7
Ontologies - Pathways
QuickGOQ96SL4
Ontology : AmiGOresponse to reactive oxygen species  catalase activity  peroxidase activity  glutathione peroxidase activity  protein binding  extracellular region  endoplasmic reticulum  endoplasmic reticulum lumen  oxidation-reduction process  
Ontology : EGO-EBIresponse to reactive oxygen species  catalase activity  peroxidase activity  glutathione peroxidase activity  protein binding  extracellular region  endoplasmic reticulum  endoplasmic reticulum lumen  oxidation-reduction process  
Pathways : KEGGGlutathione metabolism    Arachidonic acid metabolism    Thyroid hormone synthesis   
Protein Interaction DatabaseGPX7
DoCM (Curated mutations)GPX7
Wikipedia pathwaysGPX7
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerGPX7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPX7
dbVarGPX7
ClinVarGPX7
1000_GenomesGPX7 
Exome Variant ServerGPX7
SNP (GeneSNP Utah)GPX7
SNP : HGBaseGPX7
Genetic variants : HAPMAPGPX7
Genomic Variants (DGV)GPX7 [DGVbeta]
Mutations
ICGC Data PortalENSG00000116157 
Somatic Mutations in Cancer : COSMICGPX7 
CONAN: Copy Number AnalysisGPX7 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:53068043-53074723
Mutations and Diseases : HGMDGPX7
OMIM615784   
MedgenGPX7
NextProtQ96SL4 [Medical]
GENETestsGPX7
Disease Genetic AssociationGPX7
Huge Navigator GPX7 [HugePedia]  GPX7 [HugeCancerGEM]
snp3D : Map Gene to Disease2882
DGIdb (Drug Gene Interaction db)GPX7
General knowledge
Homologs : HomoloGeneGPX7
Homology/Alignments : Family Browser (UCSC)GPX7
Phylogenetic Trees/Animal Genes : TreeFamGPX7
Chemical/Protein Interactions : CTD2882
Chemical/Pharm GKB GenePA28955
Clinical trialGPX7
Cancer Resource (Charite)ENSG00000116157
Other databases
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
CoreMineGPX7
GoPubMedGPX7
iHOPGPX7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Mar 28 15:32:27 CET 2015

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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.