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GPX8 (glutathione peroxidase 8 (putative))

Identity

Alias (NCBI)EPLA847
GPx-8
GSHPx-8
UNQ847
HGNC (Hugo) GPX8
HGNC Alias symbUNQ847
EPLA847
LocusID (NCBI) 493869
Atlas_Id 64024
Location 5q11.2  [Link to chromosome band 5q11]
Location_base_pair Starts at 55160171 and ends at 55167296 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GPX8 (5q11.2) / TTLL1 (22q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)GPX8   33100
Cards
Entrez_Gene (NCBI)GPX8    glutathione peroxidase 8 (putative)
AliasesEPLA847; GPx-8; GSHPx-8; UNQ847
GeneCards (Weizmann)GPX8
Ensembl hg19 (Hinxton)ENSG00000164294 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164294 [Gene_View]  ENSG00000164294 [Sequence]  chr5:55160171-55167296 [Contig_View]  GPX8 [Vega]
ICGC DataPortalENSG00000164294
TCGA cBioPortalGPX8
AceView (NCBI)GPX8
Genatlas (Paris)GPX8
SOURCE (Princeton)GPX8
Genetics Home Reference (NIH)GPX8
Genomic and cartography
GoldenPath hg38 (UCSC)GPX8  -     chr5:55160171-55167296 +  5q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPX8  -     5q11.2   [Description]    (hg19-Feb_2009)
GoldenPathGPX8 - 5q11.2 [CytoView hg19]  GPX8 - 5q11.2 [CytoView hg38]
ImmunoBaseENSG00000164294
Genome Data Viewer NCBIGPX8 [Mapview hg19]  
OMIM617172   
Gene and transcription
Genbank (Entrez)AF086192 AK022110 AK074216 AK298545 AK307365
RefSeq transcript (Entrez)NM_001008397 NM_001306197 NM_001306198 NM_001306201
Consensus coding sequences : CCDS (NCBI)GPX8
Gene ExpressionGPX8 [ NCBI-GEO ]   GPX8 [ EBI - ARRAY_EXPRESS ]   GPX8 [ SEEK ]   GPX8 [ MEM ]
Gene Expression Viewer (FireBrowse)GPX8 [ Firebrowse - Broad ]
GenevisibleExpression of GPX8 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)493869
GTEX Portal (Tissue expression)GPX8
Human Protein AtlasENSG00000164294-GPX8 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TED1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TED1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TED1
PhosPhoSitePlusQ8TED1
Domaine pattern : Prosite (Expaxy)GLUTATHIONE_PEROXID_2 (PS00763)    GLUTATHIONE_PEROXID_3 (PS51355)   
Domains : Interpro (EBI)Glut_perox_Gpx7    Glutathione_peroxidase    GPX_CS    Thioredoxin-like_sf   
Domain families : Pfam (Sanger)GSHPx (PF00255)   
Domain families : Pfam (NCBI)pfam00255   
Conserved Domain (NCBI)GPX8
PDB (RSDB)3CYN    3KIJ   
PDB Europe3CYN    3KIJ   
PDB (PDBSum)3CYN    3KIJ   
PDB (IMB)3CYN    3KIJ   
Structural Biology KnowledgeBase3CYN    3KIJ   
SCOP (Structural Classification of Proteins)3CYN    3KIJ   
CATH (Classification of proteins structures)3CYN    3KIJ   
SuperfamilyQ8TED1
AlphaFold pdb e-kbQ8TED1   
Human Protein Atlas [tissue]ENSG00000164294-GPX8 [tissue]
HPRD17416
Protein Interaction databases
DIP (DOE-UCLA)Q8TED1
IntAct (EBI)Q8TED1
BioGRIDGPX8
STRING (EMBL)GPX8
ZODIACGPX8
Ontologies - Pathways
QuickGOQ8TED1
Ontology : AmiGOperoxidase activity  peroxidase activity  glutathione peroxidase activity  protein binding  endoplasmic reticulum lumen  integral component of membrane  cellular response to oxidative stress  cellular oxidant detoxification  
Ontology : EGO-EBIperoxidase activity  peroxidase activity  glutathione peroxidase activity  protein binding  endoplasmic reticulum lumen  integral component of membrane  cellular response to oxidative stress  cellular oxidant detoxification  
NDEx NetworkGPX8
Atlas of Cancer Signalling NetworkGPX8
Wikipedia pathwaysGPX8
Orthology - Evolution
OrthoDB493869
GeneTree (enSembl)ENSG00000164294
Phylogenetic Trees/Animal Genes : TreeFamGPX8
Homologs : HomoloGeneGPX8
Homology/Alignments : Family Browser (UCSC)GPX8
Gene fusions - Rearrangements
Fusion : QuiverGPX8
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPX8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPX8
dbVarGPX8
ClinVarGPX8
MonarchGPX8
1000_GenomesGPX8 
Exome Variant ServerGPX8
GNOMAD BrowserENSG00000164294
Varsome BrowserGPX8
ACMGGPX8 variants
VarityQ8TED1
Genomic Variants (DGV)GPX8 [DGVbeta]
DECIPHERGPX8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPX8 
Mutations
ICGC Data PortalGPX8 
TCGA Data PortalGPX8 
Broad Tumor PortalGPX8
OASIS PortalGPX8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPX8  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGPX8
Mutations and Diseases : HGMDGPX8
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGPX8
DgiDB (Drug Gene Interaction Database)GPX8
DoCM (Curated mutations)GPX8
CIViC (Clinical Interpretations of Variants in Cancer)GPX8
Cancer3DGPX8
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617172   
Orphanet
DisGeNETGPX8
MedgenGPX8
Genetic Testing Registry GPX8
NextProtQ8TED1 [Medical]
GENETestsGPX8
Target ValidationGPX8
Huge Navigator GPX8 [HugePedia]
ClinGenGPX8
Clinical trials, drugs, therapy
MyCancerGenomeGPX8
Protein Interactions : CTDGPX8
Pharm GKB GenePA164720300
PharosQ8TED1
Clinical trialGPX8
Miscellaneous
canSAR (ICR)GPX8
HarmonizomeGPX8
DataMed IndexGPX8
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGPX8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:52:04 CEST 2021

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