Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GPX8 (glutathione peroxidase 8 (putative))

Identity

Alias_symbol (synonym)UNQ847
EPLA847
Other aliasGPx-8
GSHPx-8
HGNC (Hugo) GPX8
LocusID (NCBI) 493869
Atlas_Id 64024
Location 5q11.2  [Link to chromosome band 5q11]
Location_base_pair Starts at 55160118 and ends at 55167301 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GPX8 (5q11.2) / TTLL1 (22q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPX8   33100
Cards
Entrez_Gene (NCBI)GPX8  493869  glutathione peroxidase 8 (putative)
AliasesEPLA847; GPx-8; GSHPx-8; UNQ847
GeneCards (Weizmann)GPX8
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr5:55160118-55167301 [Contig_View]  GPX8 [Vega]
TCGA cBioPortalGPX8
AceView (NCBI)GPX8
Genatlas (Paris)GPX8
WikiGenes493869
SOURCE (Princeton)GPX8
Genetics Home Reference (NIH)GPX8
Genomic and cartography
GoldenPath hg38 (UCSC)GPX8  -     chr5:55160118-55167301 +  5q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPX8  -     5q11.2   [Description]    (hg19-Feb_2009)
EnsemblGPX8 - 5q11.2 [CytoView hg19]  GPX8 - 5q11.2 [CytoView hg38]
Mapping of homologs : NCBIGPX8 [Mapview hg19]  GPX8 [Mapview hg38]
OMIM617172   
Gene and transcription
Genbank (Entrez)AF086192 AK022110 AK074216 AK298545 AK307365
RefSeq transcript (Entrez)NM_001008397 NM_001306197 NM_001306198 NM_001306201
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPX8
Cluster EST : UnigeneHs.289044 [ NCBI ]
CGAP (NCI)Hs.289044
Gene ExpressionGPX8 [ NCBI-GEO ]   GPX8 [ EBI - ARRAY_EXPRESS ]   GPX8 [ SEEK ]   GPX8 [ MEM ]
Gene Expression Viewer (FireBrowse)GPX8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)493869
GTEX Portal (Tissue expression)GPX8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TED1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TED1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TED1
Splice isoforms : SwissVarQ8TED1
PhosPhoSitePlusQ8TED1
Domaine pattern : Prosite (Expaxy)GLUTATHIONE_PEROXID_2 (PS00763)    GLUTATHIONE_PEROXID_3 (PS51355)   
Domains : Interpro (EBI)Glut_perox_Gpx7    Glutathione_peroxidase    GPX_CS    Thioredoxin-like_fold   
Domain families : Pfam (Sanger)GSHPx (PF00255)   
Domain families : Pfam (NCBI)pfam00255   
Conserved Domain (NCBI)GPX8
DMDM Disease mutations493869
Blocks (Seattle)GPX8
PDB (SRS)3CYN    3KIJ   
PDB (PDBSum)3CYN    3KIJ   
PDB (IMB)3CYN    3KIJ   
PDB (RSDB)3CYN    3KIJ   
Structural Biology KnowledgeBase3CYN    3KIJ   
SCOP (Structural Classification of Proteins)3CYN    3KIJ   
CATH (Classification of proteins structures)3CYN    3KIJ   
SuperfamilyQ8TED1
Peptide AtlasQ8TED1
HPRD17416
IPIIPI00291695   IPI00910821   IPI01018360   
Protein Interaction databases
DIP (DOE-UCLA)Q8TED1
IntAct (EBI)Q8TED1
BioGRIDGPX8
STRING (EMBL)GPX8
ZODIACGPX8
Ontologies - Pathways
QuickGOQ8TED1
Ontology : AmiGOresponse to reactive oxygen species  peroxidase activity  glutathione peroxidase activity  endoplasmic reticulum lumen  integral component of membrane  oxidation-reduction process  cellular oxidant detoxification  
Ontology : EGO-EBIresponse to reactive oxygen species  peroxidase activity  glutathione peroxidase activity  endoplasmic reticulum lumen  integral component of membrane  oxidation-reduction process  cellular oxidant detoxification  
Pathways : KEGGGlutathione metabolism    Arachidonic acid metabolism    Thyroid hormone synthesis   
NDEx NetworkGPX8
Atlas of Cancer Signalling NetworkGPX8
Wikipedia pathwaysGPX8
Orthology - Evolution
OrthoDB493869
Phylogenetic Trees/Animal Genes : TreeFamGPX8
HOVERGENQ8TED1
HOGENOMQ8TED1
Homologs : HomoloGeneGPX8
Homology/Alignments : Family Browser (UCSC)GPX8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPX8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPX8
dbVarGPX8
ClinVarGPX8
1000_GenomesGPX8 
Exome Variant ServerGPX8
ExAC (Exome Aggregation Consortium)GPX8 (select the gene name)
Genetic variants : HAPMAP493869
Genomic Variants (DGV)GPX8 [DGVbeta]
DECIPHERGPX8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPX8 
Mutations
ICGC Data PortalGPX8 
TCGA Data PortalGPX8 
Broad Tumor PortalGPX8
OASIS PortalGPX8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPX8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPX8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPX8
DgiDB (Drug Gene Interaction Database)GPX8
DoCM (Curated mutations)GPX8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPX8 (select a term)
intoGenGPX8
Cancer3DGPX8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617172   
Orphanet
MedgenGPX8
Genetic Testing Registry GPX8
NextProtQ8TED1 [Medical]
TSGene493869
GENETestsGPX8
Target ValidationGPX8
Huge Navigator GPX8 [HugePedia]
snp3D : Map Gene to Disease493869
BioCentury BCIQGPX8
ClinGenGPX8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD493869
Chemical/Pharm GKB GenePA164720300
Clinical trialGPX8
Miscellaneous
canSAR (ICR)GPX8 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPX8
EVEXGPX8
GoPubMedGPX8
iHOPGPX8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:51:23 CEST 2017

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