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GRAP (GRB2-related adaptor protein)

Identity

Other namesMGC64880
HGNC (Hugo) GRAP
Location 17p11.2
Location_base_pair Starts at 18864715 and ends at 18891061 bp from pter ( according to hg18-March_2006)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GRAP   4562
Entrez_Gene (NCBI)GRAP  10750  GRB2-related adaptor protein
Cards
GeneCards (Weizmann)GRAP
Ensembl (Hinxton)ENSG00000154016 [Gene_View]  GRAP [Vega]
AceView (NCBI)GRAP
Genatlas (Paris)GRAP
euGene (Indiana)10750
SOURCE (Stanford)NM_006613
Gene Expression (Array Express) ENSG00000154016
Genomic and cartography
GoldenPath (UCSC)GRAP  -  17p11.2   chr17:18864715-18891061 -  17p11.2   [Description]    (hg18-March_2006)
EnsemblGRAP - 17p11.2 [CytoView]
Mapping of homologs : NCBIGRAP [Mapview]
OMIM604330   
Gene and transcription
Gene : Genbank (Entrez)BC035856 BC063035 BQ056077 BT019981 CR541941
Reference sequence (RefSeq transcript) :SRSNM_006613
Reference transcript : EntrezNM_006613
RefSeq genomic : SRSAC_000149 NC_000017 NT_010718 NW_001838422 NW_001842117 NW_926301
RefSeq genomic : EntrezAC_000149 NC_000017 NT_010718 NW_001838422 NW_001842117 NW_926301
Consensus coding sequences : CCDS NCBIGRAP
Cluster EST : UnigeneHs.567416 [ SRS ] Hs.567416 [ NCBI ]
Alternative Splicing : Fast-db (Paris)6062
Protein : pattern, domain, 3D structure
Protein : UniProt/SwissProtQ13588 (SRS) Q13588 (Expasy) Q13588 (Uniprot)
With graphics : InterProQ13588
Splice isoforms : VarSplice FASTAQ13588(VarSplice FASTA)
Domaine pattern : Prosite (SRS)SH2 (PS50001)    SH3 (PS50002)   
Domain pattern : Prosite (Expaxy)SH2 (PS50001)    SH3 (PS50002)   
Domains : Interpro (SRS)Neu_cyt_fact_2    SH2    SH3_2    SH3_domain    SH3_region   
Domains : Interpro (EBI)Neu_cyt_fact_2    SH2    SH3_2    SH3_domain    SH3_region   
Related proteins : CluSTrQ13588
Domain families : Pfam SRSSH2 (PF00017)    SH3_1 (PF00018)    SH3_2 (PF07653)   
Domain families : Pfam SangerSH2 (PF00017)    SH3_1 (PF00018)    SH3_2 (PF07653)   
Domain families : Pfam NCBIpfam00017    pfam00018    pfam07653   
Domain families : Smart EMBLSH2 (SM00252)  SH3 (SM00326)  
Blocks (Seattle)Q13588
Crystal structure of protein : PDB SRS
Crystal structure of protein : PDBSum
Crystal structure of protein : IMB
Crystal structure of protein : PDB RSDB
HPRD05062
Protein Interaction databases
DIP (DOE-UCLA)Q13588
IntAct (EBI)Q13588
Polymorphism : SNP, mutations, diseases
Single Nucleotide Polymorphism (SNP) : dbSNP NCBIGRAP
SNP : GeneSNP UtahGRAP
SNP : HGBaseGRAP
Genetic variants : HAPMAPGRAP
Somatic Mutations in Cancer : COSMICGRAP 
Mutations and Diseases : HGMDGRAP
Hereditary diseases : OMIM604330   
Hereditary diseases : GENETests604330   
Diseases : Genetic AssociationGRAP
General knowledge
Homologs : HomoloGeneGRAP
Homology/Alignments : Family Browser UCSCGRAP
Phylogenetic Trees/Animal Genes : TreeFamGRAP
Chemical/Protein Interactions : CTD10750
Keywords Ontology : AmiGOSH3/SH2 adaptor activity  protein binding  cytoplasm  Ras protein signal transduction  cell-cell signaling  
Keywords Ontology : EGO-EBISH3/SH2 adaptor activity  protein binding  cytoplasm  Ras protein signal transduction  cell-cell signaling  
Pathways : BIOCARTA
Pathways : KEGG
Other databases
Probes
Probes : ImagenesGRAP Related clones (RZPD - Berlin)
Literature
PubMed13 Pubmed reference(s) in Entrez
PubGeneGRAP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated03-2009Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 27 10:45:56 CET 2010
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