Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GRHL1 (grainyhead like transcription factor 1)

Identity

Alias_namesTFCP2L2
transcription factor CP2-like 2
grainyhead-like 1 (Drosophila)
Alias_symbol (synonym)LBP-32
MGR
Other aliasLBP32
NH32
HGNC (Hugo) GRHL1
LocusID (NCBI) 29841
Atlas_Id 55619
Location 2p25.1  [Link to chromosome band 2p25]
Location_base_pair Starts at 9951663 and ends at 10002284 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARL17A (17q21.31) / GRHL1 (2p25.1)C6orf62 (6p22.3) / GRHL1 (2p25.1)GOLGA4 (3p22.2) / GRHL1 (2p25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GRHL1   17923
Cards
Entrez_Gene (NCBI)GRHL1  29841  grainyhead like transcription factor 1
AliasesLBP32; MGR; NH32; TFCP2L2
GeneCards (Weizmann)GRHL1
Ensembl hg19 (Hinxton)ENSG00000134317 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134317 [Gene_View]  chr2:9951663-10002284 [Contig_View]  GRHL1 [Vega]
ICGC DataPortalENSG00000134317
TCGA cBioPortalGRHL1
AceView (NCBI)GRHL1
Genatlas (Paris)GRHL1
WikiGenes29841
SOURCE (Princeton)GRHL1
Genetics Home Reference (NIH)GRHL1
Genomic and cartography
GoldenPath hg38 (UCSC)GRHL1  -     chr2:9951663-10002284 +  2p25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GRHL1  -     2p25.1   [Description]    (hg19-Feb_2009)
EnsemblGRHL1 - 2p25.1 [CytoView hg19]  GRHL1 - 2p25.1 [CytoView hg38]
Mapping of homologs : NCBIGRHL1 [Mapview hg19]  GRHL1 [Mapview hg38]
OMIM609786   
Gene and transcription
Genbank (Entrez)AA234992 AF198489 AF411210 AI686262 AK293855
RefSeq transcript (Entrez)NM_198182
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GRHL1
Cluster EST : UnigeneHs.418493 [ NCBI ]
CGAP (NCI)Hs.418493
Alternative Splicing GalleryENSG00000134317
Gene ExpressionGRHL1 [ NCBI-GEO ]   GRHL1 [ EBI - ARRAY_EXPRESS ]   GRHL1 [ SEEK ]   GRHL1 [ MEM ]
Gene Expression Viewer (FireBrowse)GRHL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29841
GTEX Portal (Tissue expression)GRHL1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZI5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZI5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZI5
Splice isoforms : SwissVarQ9NZI5
PhosPhoSitePlusQ9NZI5
Domains : Interpro (EBI)CP2   
Domain families : Pfam (Sanger)CP2 (PF04516)   
Domain families : Pfam (NCBI)pfam04516   
Conserved Domain (NCBI)GRHL1
DMDM Disease mutations29841
Blocks (Seattle)GRHL1
SuperfamilyQ9NZI5
Human Protein AtlasENSG00000134317
Peptide AtlasQ9NZI5
HPRD18176
IPIIPI00185043   IPI00181670   IPI00739435   IPI01010740   IPI00946261   
Protein Interaction databases
DIP (DOE-UCLA)Q9NZI5
IntAct (EBI)Q9NZI5
FunCoupENSG00000134317
BioGRIDGRHL1
STRING (EMBL)GRHL1
ZODIACGRHL1
Ontologies - Pathways
QuickGOQ9NZI5
Ontology : AmiGORNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  desmosome organization  nucleus  nucleoplasm  nucleoplasm  Golgi apparatus  cytosol  transcription from RNA polymerase II promoter  epidermis development  chromatin DNA binding  intracellular membrane-bounded organelle  sequence-specific DNA binding  transcription regulatory region DNA binding  regulation of keratinocyte differentiation  positive regulation of transcription from RNA polymerase II promoter  establishment of skin barrier  
Ontology : EGO-EBIRNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  desmosome organization  nucleus  nucleoplasm  nucleoplasm  Golgi apparatus  cytosol  transcription from RNA polymerase II promoter  epidermis development  chromatin DNA binding  intracellular membrane-bounded organelle  sequence-specific DNA binding  transcription regulatory region DNA binding  regulation of keratinocyte differentiation  positive regulation of transcription from RNA polymerase II promoter  establishment of skin barrier  
NDEx NetworkGRHL1
Atlas of Cancer Signalling NetworkGRHL1
Wikipedia pathwaysGRHL1
Orthology - Evolution
OrthoDB29841
GeneTree (enSembl)ENSG00000134317
Phylogenetic Trees/Animal Genes : TreeFamGRHL1
HOVERGENQ9NZI5
HOGENOMQ9NZI5
Homologs : HomoloGeneGRHL1
Homology/Alignments : Family Browser (UCSC)GRHL1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGRHL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GRHL1
dbVarGRHL1
ClinVarGRHL1
1000_GenomesGRHL1 
Exome Variant ServerGRHL1
ExAC (Exome Aggregation Consortium)GRHL1 (select the gene name)
Genetic variants : HAPMAP29841
Genomic Variants (DGV)GRHL1 [DGVbeta]
DECIPHERGRHL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGRHL1 
Mutations
ICGC Data PortalGRHL1 
TCGA Data PortalGRHL1 
Broad Tumor PortalGRHL1
OASIS PortalGRHL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGRHL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGRHL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GRHL1
DgiDB (Drug Gene Interaction Database)GRHL1
DoCM (Curated mutations)GRHL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GRHL1 (select a term)
intoGenGRHL1
Cancer3DGRHL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609786   
Orphanet
MedgenGRHL1
Genetic Testing Registry GRHL1
NextProtQ9NZI5 [Medical]
TSGene29841
GENETestsGRHL1
Target ValidationGRHL1
Huge Navigator GRHL1 [HugePedia]
snp3D : Map Gene to Disease29841
BioCentury BCIQGRHL1
ClinGenGRHL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29841
Chemical/Pharm GKB GenePA134971477
Clinical trialGRHL1
Miscellaneous
canSAR (ICR)GRHL1 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGRHL1
EVEXGRHL1
GoPubMedGRHL1
iHOPGRHL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 17:02:28 CEST 2017

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