Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GRIA3 (glutamate ionotropic receptor AMPA type subunit 3)

Identity

Alias_namesGLUR3
glutamate receptor
Alias_symbol (synonym)GluA3
GLURC
MRX94
Other aliasGLUR-C
GLUR-K3
HGNC (Hugo) GRIA3
LocusID (NCBI) 2892
Atlas_Id 46508
Location Xq25  [Link to chromosome band Xq25]
Location_base_pair Starts at 123184243 and ends at 123490915 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AHNAK (11q12.3) / GRIA3 (Xq25)DAPK1 (9q21.33) / GRIA3 (Xq25)GRIA3 (Xq25) / PHF20 (20q11.22)
STAG2 (Xq25) / GRIA3 (Xq25)STAG2 Xq25 / GRIA3 Xq25

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GRIA3   4573
Cards
Entrez_Gene (NCBI)GRIA3  2892  glutamate ionotropic receptor AMPA type subunit 3
AliasesGLUR-C; GLUR-K3; GLUR3; GLURC; 
GluA3; MRX94
GeneCards (Weizmann)GRIA3
Ensembl hg19 (Hinxton)ENSG00000125675 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000125675 [Gene_View]  chrX:123184243-123490915 [Contig_View]  GRIA3 [Vega]
ICGC DataPortalENSG00000125675
TCGA cBioPortalGRIA3
AceView (NCBI)GRIA3
Genatlas (Paris)GRIA3
WikiGenes2892
SOURCE (Princeton)GRIA3
Genetics Home Reference (NIH)GRIA3
Genomic and cartography
GoldenPath hg38 (UCSC)GRIA3  -     chrX:123184243-123490915 +  Xq25   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GRIA3  -     Xq25   [Description]    (hg19-Feb_2009)
EnsemblGRIA3 - Xq25 [CytoView hg19]  GRIA3 - Xq25 [CytoView hg38]
Mapping of homologs : NCBIGRIA3 [Mapview hg19]  GRIA3 [Mapview hg38]
OMIM300699   305915   
Gene and transcription
Genbank (Entrez)AK297136 AW166130 BC032004 BC117464 BE504553
RefSeq transcript (Entrez)NM_000828 NM_001256743 NM_007325 NM_181894
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GRIA3
Cluster EST : UnigeneHs.377070 [ NCBI ]
CGAP (NCI)Hs.377070
Alternative Splicing GalleryENSG00000125675
Gene ExpressionGRIA3 [ NCBI-GEO ]   GRIA3 [ EBI - ARRAY_EXPRESS ]   GRIA3 [ SEEK ]   GRIA3 [ MEM ]
Gene Expression Viewer (FireBrowse)GRIA3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2892
GTEX Portal (Tissue expression)GRIA3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP42263   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP42263  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP42263
Splice isoforms : SwissVarP42263
PhosPhoSitePlusP42263
Domains : Interpro (EBI)ANF_lig-bd_rcpt    Glu/Gly-bd    Iono_rcpt_met    Iontro_rcpt    Peripla_BP_I   
Domain families : Pfam (Sanger)ANF_receptor (PF01094)    Lig_chan (PF00060)    Lig_chan-Glu_bd (PF10613)   
Domain families : Pfam (NCBI)pfam01094    pfam00060    pfam10613   
Domain families : Smart (EMBL)Lig_chan-Glu_bd (SM00918)  PBPe (SM00079)  
Conserved Domain (NCBI)GRIA3
DMDM Disease mutations2892
Blocks (Seattle)GRIA3
SuperfamilyP42263
Human Protein AtlasENSG00000125675
Peptide AtlasP42263
HPRD02378
IPIIPI00298700   IPI00219315   IPI00921875   IPI01012695   IPI00843853   IPI00607756   
Protein Interaction databases
DIP (DOE-UCLA)P42263
IntAct (EBI)P42263
FunCoupENSG00000125675
BioGRIDGRIA3
STRING (EMBL)GRIA3
ZODIACGRIA3
Ontologies - Pathways
QuickGOP42263
Ontology : AmiGOAMPA glutamate receptor activity  excitatory extracellular ligand-gated ion channel activity  extracellular-glutamate-gated ion channel activity  plasma membrane  transport  glutamate receptor signaling pathway  cell junction  endocytic vesicle membrane  AMPA glutamate receptor complex  AMPA glutamate receptor complex  ion transmembrane transport  ionotropic glutamate receptor signaling pathway  postsynaptic membrane  excitatory postsynaptic potential  
Ontology : EGO-EBIAMPA glutamate receptor activity  excitatory extracellular ligand-gated ion channel activity  extracellular-glutamate-gated ion channel activity  plasma membrane  transport  glutamate receptor signaling pathway  cell junction  endocytic vesicle membrane  AMPA glutamate receptor complex  AMPA glutamate receptor complex  ion transmembrane transport  ionotropic glutamate receptor signaling pathway  postsynaptic membrane  excitatory postsynaptic potential  
Pathways : KEGG   
NDEx NetworkGRIA3
Atlas of Cancer Signalling NetworkGRIA3
Wikipedia pathwaysGRIA3
Orthology - Evolution
OrthoDB2892
GeneTree (enSembl)ENSG00000125675
Phylogenetic Trees/Animal Genes : TreeFamGRIA3
HOVERGENP42263
HOGENOMP42263
Homologs : HomoloGeneGRIA3
Homology/Alignments : Family Browser (UCSC)GRIA3
Gene fusions - Rearrangements
Fusion: TCGASTAG2 Xq25 GRIA3 Xq25 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGRIA3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GRIA3
dbVarGRIA3
ClinVarGRIA3
1000_GenomesGRIA3 
Exome Variant ServerGRIA3
ExAC (Exome Aggregation Consortium)GRIA3 (select the gene name)
Genetic variants : HAPMAP2892
Genomic Variants (DGV)GRIA3 [DGVbeta]
DECIPHERGRIA3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGRIA3 
Mutations
ICGC Data PortalGRIA3 
TCGA Data PortalGRIA3 
Broad Tumor PortalGRIA3
OASIS PortalGRIA3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGRIA3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGRIA3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch GRIA3
DgiDB (Drug Gene Interaction Database)GRIA3
DoCM (Curated mutations)GRIA3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GRIA3 (select a term)
intoGenGRIA3
Cancer3DGRIA3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300699    305915   
Orphanet22360   
MedgenGRIA3
Genetic Testing Registry GRIA3
NextProtP42263 [Medical]
TSGene2892
GENETestsGRIA3
Target ValidationGRIA3
Huge Navigator GRIA3 [HugePedia]
snp3D : Map Gene to Disease2892
BioCentury BCIQGRIA3
ClinGenGRIA3 (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2892
Chemical/Pharm GKB GenePA28968
Clinical trialGRIA3
Miscellaneous
canSAR (ICR)GRIA3 (select the gene name)
Probes
Litterature
PubMed64 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGRIA3
EVEXGRIA3
GoPubMedGRIA3
iHOPGRIA3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Aug 1 17:02:28 CEST 2017

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