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GRID1 (glutamate ionotropic receptor delta type subunit 1)

Identity

Alias (NCBI)GluD1
HGNC (Hugo) GRID1
HGNC Alias symbGluD1
KIAA1220
HGNC Previous nameglutamate receptor, ionotropic, delta 1
LocusID (NCBI) 2894
Atlas_Id 40752
Location 10q23.1  [Link to chromosome band 10q23]
Location_base_pair Starts at 85599553 and ends at 86366795 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
COL1A1 (17q21.33) / GRID1 (10q23.1)CYTH3 (7p22.1) / GRID1 (10q23.1)DPM1 (20q13.13) / GRID1 (10q23.1)
GRID1 (10q23.1) / HECTD2 (10q23.32)GRID1 (10q23.1) / NFIC (19p13.3)GRID1 (10q23.1) / PGPEP1L (15q26.3)
GRID1 (10q23.1) / WAPL (10q23.2)SGMS1 (10q11.23) / GRID1 (10q23.1)TRAPPC10 (21q22.3) / GRID1 (10q23.1)
CYTH3 7p22.1 / GRID1 10q23.1DPM1 20q13.13 / GRID1 10q23.1GRID1 10q23.1 / HECTD2 10q23.32
GRID1 10q23.1 / PGPEP1L 15q26.3SGMS1 10q11.23 / GRID1 10q23.1TRAPPC10 21q22.3 / GRID1 10q23.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(10;20)(q23;q13) DPM1/GRID1
t(10;20)(q23;q13) GRID1/DPM1

External links

 

Nomenclature
HGNC (Hugo)GRID1   4575
Cards
Entrez_Gene (NCBI)GRID1    glutamate ionotropic receptor delta type subunit 1
AliasesGluD1
GeneCards (Weizmann)GRID1
Ensembl hg19 (Hinxton)ENSG00000182771 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000182771 [Gene_View]  ENSG00000182771 [Sequence]  chr10:85599553-86366795 [Contig_View]  GRID1 [Vega]
ICGC DataPortalENSG00000182771
TCGA cBioPortalGRID1
AceView (NCBI)GRID1
Genatlas (Paris)GRID1
SOURCE (Princeton)GRID1
Genetics Home Reference (NIH)GRID1
Genomic and cartography
GoldenPath hg38 (UCSC)GRID1  -     chr10:85599553-86366795 -  10q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GRID1  -     10q23.1   [Description]    (hg19-Feb_2009)
GoldenPathGRID1 - 10q23.1 [CytoView hg19]  GRID1 - 10q23.1 [CytoView hg38]
ImmunoBaseENSG00000182771
Genome Data Viewer NCBIGRID1 [Mapview hg19]  
OMIM610659   
Gene and transcription
Genbank (Entrez)AB033046 AK127168 AK293104 AK302192 BC039263
RefSeq transcript (Entrez)NM_017551
Consensus coding sequences : CCDS (NCBI)GRID1
Gene ExpressionGRID1 [ NCBI-GEO ]   GRID1 [ EBI - ARRAY_EXPRESS ]   GRID1 [ SEEK ]   GRID1 [ MEM ]
Gene Expression Viewer (FireBrowse)GRID1 [ Firebrowse - Broad ]
GenevisibleExpression of GRID1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2894
GTEX Portal (Tissue expression)GRID1
Human Protein AtlasENSG00000182771-GRID1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULK0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9ULK0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9ULK0
PhosPhoSitePlusQ9ULK0
Domains : Interpro (EBI)ANF_lig-bd_rcpt    Glu/Gly-bd    Iono_rcpt_met    Iontro_rcpt    Peripla_BP_I   
Domain families : Pfam (Sanger)ANF_receptor (PF01094)    Lig_chan (PF00060)    Lig_chan-Glu_bd (PF10613)   
Domain families : Pfam (NCBI)pfam01094    pfam00060    pfam10613   
Domain families : Smart (EMBL)Lig_chan-Glu_bd (SM00918)  PBPe (SM00079)  
Conserved Domain (NCBI)GRID1
SuperfamilyQ9ULK0
AlphaFold pdb e-kbQ9ULK0   
Human Protein Atlas [tissue]ENSG00000182771-GRID1 [tissue]
HPRD17078
Protein Interaction databases
DIP (DOE-UCLA)Q9ULK0
IntAct (EBI)Q9ULK0
BioGRIDGRID1
STRING (EMBL)GRID1
ZODIACGRID1
Ontologies - Pathways
QuickGOQ9ULK0
Ontology : AmiGOionotropic glutamate receptor activity  plasma membrane  glutamate receptor activity  ligand-gated ion channel activity  ion transmembrane transport  social behavior  ionotropic glutamate receptor signaling pathway  synaptic transmission, glutamatergic  signaling receptor activity  postsynaptic membrane  modulation of chemical synaptic transmission  regulation of postsynaptic membrane potential  extracellular exosome  glutamatergic synapse  integral component of postsynaptic density membrane  transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential  
Ontology : EGO-EBIionotropic glutamate receptor activity  plasma membrane  glutamate receptor activity  ligand-gated ion channel activity  ion transmembrane transport  social behavior  ionotropic glutamate receptor signaling pathway  synaptic transmission, glutamatergic  signaling receptor activity  postsynaptic membrane  modulation of chemical synaptic transmission  regulation of postsynaptic membrane potential  extracellular exosome  glutamatergic synapse  integral component of postsynaptic density membrane  transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkGRID1
Atlas of Cancer Signalling NetworkGRID1
Wikipedia pathwaysGRID1
Orthology - Evolution
OrthoDB2894
GeneTree (enSembl)ENSG00000182771
Phylogenetic Trees/Animal Genes : TreeFamGRID1
Homologs : HomoloGeneGRID1
Homology/Alignments : Family Browser (UCSC)GRID1
Gene fusions - Rearrangements
Fusion : MitelmanCYTH3/GRID1 [7p22.1/10q23.1]  
Fusion : MitelmanDPM1/GRID1 [20q13.13/10q23.1]  
Fusion : MitelmanGRID1/HECTD2 [10q23.1/10q23.32]  
Fusion : MitelmanGRID1/PGPEP1L [10q23.1/15q26.3]  
Fusion : MitelmanSGMS1/GRID1 [10q11.23/10q23.1]  
Fusion : MitelmanTRAPPC10/GRID1 [21q22.3/10q23.1]  
Fusion : QuiverGRID1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGRID1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GRID1
dbVarGRID1
ClinVarGRID1
MonarchGRID1
1000_GenomesGRID1 
Exome Variant ServerGRID1
GNOMAD BrowserENSG00000182771
Varsome BrowserGRID1
ACMGGRID1 variants
VarityQ9ULK0
Genomic Variants (DGV)GRID1 [DGVbeta]
DECIPHERGRID1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGRID1 
Mutations
ICGC Data PortalGRID1 
TCGA Data PortalGRID1 
Broad Tumor PortalGRID1
OASIS PortalGRID1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGRID1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGRID1
Mutations and Diseases : HGMDGRID1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGRID1
DgiDB (Drug Gene Interaction Database)GRID1
DoCM (Curated mutations)GRID1
CIViC (Clinical Interpretations of Variants in Cancer)GRID1
Cancer3DGRID1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610659   
Orphanet
DisGeNETGRID1
MedgenGRID1
Genetic Testing Registry GRID1
NextProtQ9ULK0 [Medical]
GENETestsGRID1
Target ValidationGRID1
Huge Navigator GRID1 [HugePedia]
ClinGenGRID1 (curated)
Clinical trials, drugs, therapy
MyCancerGenomeGRID1
Protein Interactions : CTDGRID1
Pharm GKB GenePA28970
PharosQ9ULK0
Clinical trialGRID1
Miscellaneous
canSAR (ICR)GRID1
HarmonizomeGRID1
DataMed IndexGRID1
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGRID1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:11:30 CEST 2021
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