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GRID2 (glutamate ionotropic receptor delta type subunit 2)

Identity

Alias_namesglutamate receptor
Alias_symbol (synonym)GluD2
GluR-delta-2
Other aliasSCAR18
HGNC (Hugo) GRID2
LocusID (NCBI) 2895
Atlas_Id 40753
Location 4q22.1  [Link to chromosome band 4q22]
Location_base_pair Starts at 92304399 and ends at 93774555 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GNPDA2 (4p12) / GRID2 (4q22.1)GRID2 (4q22.1) / PRDX6 (1q25.1)RANGAP1 (22q13.2) / GRID2 (4q22.1)
GNPDA2 4p12 / GRID2 4q22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GRID2   4576
Cards
Entrez_Gene (NCBI)GRID2  2895  glutamate ionotropic receptor delta type subunit 2
AliasesGluD2; SCAR18
GeneCards (Weizmann)GRID2
Ensembl hg19 (Hinxton)ENSG00000152208 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000152208 [Gene_View]  chr4:92304399-93774555 [Contig_View]  GRID2 [Vega]
ICGC DataPortalENSG00000152208
TCGA cBioPortalGRID2
AceView (NCBI)GRID2
Genatlas (Paris)GRID2
WikiGenes2895
SOURCE (Princeton)GRID2
Genetics Home Reference (NIH)GRID2
Genomic and cartography
GoldenPath hg38 (UCSC)GRID2  -     chr4:92304399-93774555 +  4q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GRID2  -     4q22.1   [Description]    (hg19-Feb_2009)
EnsemblGRID2 - 4q22.1 [CytoView hg19]  GRID2 - 4q22.1 [CytoView hg38]
Mapping of homologs : NCBIGRID2 [Mapview hg19]  GRID2 [Mapview hg38]
OMIM602368   616204   
Gene and transcription
Genbank (Entrez)AB209318 AF009014 AK302355 AK308611 AK310262
RefSeq transcript (Entrez)NM_001286838 NM_001510
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GRID2
Cluster EST : UnigeneHs.480281 [ NCBI ]
CGAP (NCI)Hs.480281
Alternative Splicing GalleryENSG00000152208
Gene ExpressionGRID2 [ NCBI-GEO ]   GRID2 [ EBI - ARRAY_EXPRESS ]   GRID2 [ SEEK ]   GRID2 [ MEM ]
Gene Expression Viewer (FireBrowse)GRID2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2895
GTEX Portal (Tissue expression)GRID2
Human Protein AtlasENSG00000152208-GRID2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43424   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43424  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43424
Splice isoforms : SwissVarO43424
PhosPhoSitePlusO43424
Domains : Interpro (EBI)ANF_lig-bd_rcpt    Glu/Gly-bd    Iono_rcpt_met    Iontro_rcpt    Peripla_BP_I   
Domain families : Pfam (Sanger)ANF_receptor (PF01094)    Lig_chan (PF00060)    Lig_chan-Glu_bd (PF10613)   
Domain families : Pfam (NCBI)pfam01094    pfam00060    pfam10613   
Domain families : Smart (EMBL)Lig_chan-Glu_bd (SM00918)  PBPe (SM00079)  
Conserved Domain (NCBI)GRID2
DMDM Disease mutations2895
Blocks (Seattle)GRID2
PDB (SRS)5KC8    5KCA   
PDB (PDBSum)5KC8    5KCA   
PDB (IMB)5KC8    5KCA   
PDB (RSDB)5KC8    5KCA   
Structural Biology KnowledgeBase5KC8    5KCA   
SCOP (Structural Classification of Proteins)5KC8    5KCA   
CATH (Classification of proteins structures)5KC8    5KCA   
SuperfamilyO43424
Human Protein Atlas [tissue]ENSG00000152208-GRID2 [tissue]
Peptide AtlasO43424
HPRD06781
IPIIPI00747494   IPI00963845   IPI00966847   IPI01017947   IPI00965600   
Protein Interaction databases
DIP (DOE-UCLA)O43424
IntAct (EBI)O43424
FunCoupENSG00000152208
BioGRIDGRID2
STRING (EMBL)GRID2
ZODIACGRID2
Ontologies - Pathways
QuickGOO43424
Ontology : AmiGOionotropic glutamate receptor activity  extracellular-glutamate-gated ion channel activity  plasma membrane  integral component of plasma membrane  transport  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  glutamate receptor signaling pathway  glutamate receptor activity  ionotropic glutamate receptor complex  regulation of neuron projection development  cerebellar granule cell differentiation  cell junction  PDZ domain binding  ion transmembrane transport  cellular protein localization  ionotropic glutamate receptor signaling pathway  synaptic transmission, glutamatergic  dendritic spine  regulation of neuron apoptotic process  synapse  postsynaptic membrane  excitatory postsynaptic potential  prepulse inhibition  scaffold protein binding  
Ontology : EGO-EBIionotropic glutamate receptor activity  extracellular-glutamate-gated ion channel activity  plasma membrane  integral component of plasma membrane  transport  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  glutamate receptor signaling pathway  glutamate receptor activity  ionotropic glutamate receptor complex  regulation of neuron projection development  cerebellar granule cell differentiation  cell junction  PDZ domain binding  ion transmembrane transport  cellular protein localization  ionotropic glutamate receptor signaling pathway  synaptic transmission, glutamatergic  dendritic spine  regulation of neuron apoptotic process  synapse  postsynaptic membrane  excitatory postsynaptic potential  prepulse inhibition  scaffold protein binding  
Pathways : KEGGNeuroactive ligand-receptor interaction    Long-term depression   
NDEx NetworkGRID2
Atlas of Cancer Signalling NetworkGRID2
Wikipedia pathwaysGRID2
Orthology - Evolution
OrthoDB2895
GeneTree (enSembl)ENSG00000152208
Phylogenetic Trees/Animal Genes : TreeFamGRID2
HOVERGENO43424
HOGENOMO43424
Homologs : HomoloGeneGRID2
Homology/Alignments : Family Browser (UCSC)GRID2
Gene fusions - Rearrangements
Fusion : MitelmanGNPDA2/GRID2 [4p12/4q22.1]  [t(4;4)(p12;q22)]  
Fusion: TCGAGNPDA2 4p12 GRID2 4q22.1 BRCA
Fusion: Tumor Portal GRID2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGRID2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GRID2
dbVarGRID2
ClinVarGRID2
1000_GenomesGRID2 
Exome Variant ServerGRID2
ExAC (Exome Aggregation Consortium)ENSG00000152208
GNOMAD BrowserENSG00000152208
Genetic variants : HAPMAP2895
Genomic Variants (DGV)GRID2 [DGVbeta]
DECIPHERGRID2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGRID2 
Mutations
ICGC Data PortalGRID2 
TCGA Data PortalGRID2 
Broad Tumor PortalGRID2
OASIS PortalGRID2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGRID2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGRID2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GRID2
DgiDB (Drug Gene Interaction Database)GRID2
DoCM (Curated mutations)GRID2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GRID2 (select a term)
intoGenGRID2
Cancer3DGRID2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602368    616204   
Orphanet22303   
MedgenGRID2
Genetic Testing Registry GRID2
NextProtO43424 [Medical]
TSGene2895
GENETestsGRID2
Target ValidationGRID2
Huge Navigator GRID2 [HugePedia]
snp3D : Map Gene to Disease2895
BioCentury BCIQGRID2
ClinGenGRID2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2895
Chemical/Pharm GKB GenePA28971
Clinical trialGRID2
Miscellaneous
canSAR (ICR)GRID2 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGRID2
EVEXGRID2
GoPubMedGRID2
iHOPGRID2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:51:59 CET 2017

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