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GRIN2D (glutamate ionotropic receptor NMDA type subunit 2D)

Identity

Alias_namesNMDAR2D
glutamate receptor
Alias_symbol (synonym)GluN2D
EB11
NR2D
Other aliasEIEE46
HGNC (Hugo) GRIN2D
LocusID (NCBI) 2906
Atlas_Id 52665
Location 19q13.33  [Link to chromosome band 19q13]
Location_base_pair Starts at 48394875 and ends at 48444931 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RHPN2 (19q13.11) / GRIN2D (19q13.33)RHPN2 19q13.11 / GRIN2D 19q13.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GRIN2D   4588
Cards
Entrez_Gene (NCBI)GRIN2D  2906  glutamate ionotropic receptor NMDA type subunit 2D
AliasesEB11; EIEE46; GluN2D; NMDAR2D; 
NR2D
GeneCards (Weizmann)GRIN2D
Ensembl hg19 (Hinxton)ENSG00000105464 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105464 [Gene_View]  chr19:48394875-48444931 [Contig_View]  GRIN2D [Vega]
ICGC DataPortalENSG00000105464
TCGA cBioPortalGRIN2D
AceView (NCBI)GRIN2D
Genatlas (Paris)GRIN2D
WikiGenes2906
SOURCE (Princeton)GRIN2D
Genetics Home Reference (NIH)GRIN2D
Genomic and cartography
GoldenPath hg38 (UCSC)GRIN2D  -     chr19:48394875-48444931 +  19q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GRIN2D  -     19q13.33   [Description]    (hg19-Feb_2009)
EnsemblGRIN2D - 19q13.33 [CytoView hg19]  GRIN2D - 19q13.33 [CytoView hg38]
Mapping of homologs : NCBIGRIN2D [Mapview hg19]  GRIN2D [Mapview hg38]
OMIM602717   617162   
Gene and transcription
Genbank (Entrez)AB209292 AW139866 BC169223 U77783
RefSeq transcript (Entrez)NM_000836
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GRIN2D
Cluster EST : UnigeneHs.445015 [ NCBI ]
CGAP (NCI)Hs.445015
Alternative Splicing GalleryENSG00000105464
Gene ExpressionGRIN2D [ NCBI-GEO ]   GRIN2D [ EBI - ARRAY_EXPRESS ]   GRIN2D [ SEEK ]   GRIN2D [ MEM ]
Gene Expression Viewer (FireBrowse)GRIN2D [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2906
GTEX Portal (Tissue expression)GRIN2D
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15399   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15399  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15399
Splice isoforms : SwissVarO15399
PhosPhoSitePlusO15399
Domains : Interpro (EBI)ANF_lig-bd_rcpt    Glu/Gly-bd    Iono_rcpt_met    Iontro_rcpt    Peripla_BP_I   
Domain families : Pfam (Sanger)ANF_receptor (PF01094)    Lig_chan (PF00060)    Lig_chan-Glu_bd (PF10613)   
Domain families : Pfam (NCBI)pfam01094    pfam00060    pfam10613   
Domain families : Smart (EMBL)Lig_chan-Glu_bd (SM00918)  PBPe (SM00079)  
Conserved Domain (NCBI)GRIN2D
DMDM Disease mutations2906
Blocks (Seattle)GRIN2D
SuperfamilyO15399
Human Protein AtlasENSG00000105464
Peptide AtlasO15399
HPRD04095
IPIIPI00006217   
Protein Interaction databases
DIP (DOE-UCLA)O15399
IntAct (EBI)O15399
FunCoupENSG00000105464
BioGRIDGRIN2D
STRING (EMBL)GRIN2D
ZODIACGRIN2D
Ontologies - Pathways
QuickGOO15399
Ontology : AmiGOMAPK cascade  startle response  ionotropic glutamate receptor activity  NMDA glutamate receptor activity  Ras guanyl-nucleotide exchange factor activity  extracellular-glutamate-gated ion channel activity  protein binding  intracellular  plasma membrane  signal transduction  adult locomotory behavior  integral component of membrane  cell junction  ion transmembrane transport  regulation of ion transmembrane transport  ionotropic glutamate receptor signaling pathway  positive regulation of GTPase activity  postsynaptic membrane  regulation of sensory perception of pain  excitatory postsynaptic potential  
Ontology : EGO-EBIMAPK cascade  startle response  ionotropic glutamate receptor activity  NMDA glutamate receptor activity  Ras guanyl-nucleotide exchange factor activity  extracellular-glutamate-gated ion channel activity  protein binding  intracellular  plasma membrane  signal transduction  adult locomotory behavior  integral component of membrane  cell junction  ion transmembrane transport  regulation of ion transmembrane transport  ionotropic glutamate receptor signaling pathway  positive regulation of GTPase activity  postsynaptic membrane  regulation of sensory perception of pain  excitatory postsynaptic potential  
Pathways : BIOCARTANitric Oxide Signaling Pathway [Genes]   
Pathways : KEGG   
NDEx NetworkGRIN2D
Atlas of Cancer Signalling NetworkGRIN2D
Wikipedia pathwaysGRIN2D
Orthology - Evolution
OrthoDB2906
GeneTree (enSembl)ENSG00000105464
Phylogenetic Trees/Animal Genes : TreeFamGRIN2D
HOVERGENO15399
HOGENOMO15399
Homologs : HomoloGeneGRIN2D
Homology/Alignments : Family Browser (UCSC)GRIN2D
Gene fusions - Rearrangements
Fusion : MitelmanRHPN2/GRIN2D [19q13.11/19q13.33]  [t(19;19)(q13;q13)]  
Fusion: TCGARHPN2 19q13.11 GRIN2D 19q13.33 OV
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGRIN2D [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GRIN2D
dbVarGRIN2D
ClinVarGRIN2D
1000_GenomesGRIN2D 
Exome Variant ServerGRIN2D
ExAC (Exome Aggregation Consortium)GRIN2D (select the gene name)
Genetic variants : HAPMAP2906
Genomic Variants (DGV)GRIN2D [DGVbeta]
DECIPHERGRIN2D [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGRIN2D 
Mutations
ICGC Data PortalGRIN2D 
TCGA Data PortalGRIN2D 
Broad Tumor PortalGRIN2D
OASIS PortalGRIN2D [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGRIN2D  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGRIN2D
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GRIN2D
DgiDB (Drug Gene Interaction Database)GRIN2D
DoCM (Curated mutations)GRIN2D (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GRIN2D (select a term)
intoGenGRIN2D
Cancer3DGRIN2D(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602717    617162   
Orphanet
MedgenGRIN2D
Genetic Testing Registry GRIN2D
NextProtO15399 [Medical]
TSGene2906
GENETestsGRIN2D
Target ValidationGRIN2D
Huge Navigator GRIN2D [HugePedia]
snp3D : Map Gene to Disease2906
BioCentury BCIQGRIN2D
ClinGenGRIN2D
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2906
Chemical/Pharm GKB GenePA28982
Clinical trialGRIN2D
Miscellaneous
canSAR (ICR)GRIN2D (select the gene name)
Probes
Litterature
PubMed71 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGRIN2D
EVEXGRIN2D
GoPubMedGRIN2D
iHOPGRIN2D
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:36:01 CEST 2017

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