Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GRINA (glutamate ionotropic receptor NMDA type subunit associated protein 1)

Identity

Alias_namesNMDARA1
glutamate receptor
Alias_symbol (synonym)HNRGW
TMBIM3
LFG1
Other alias
HGNC (Hugo) GRINA
LocusID (NCBI) 2907
Atlas_Id 50312
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 143990058 and ends at 143993415 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
COPS7A (12p13.31) / GRINA (8q24.3)GRINA (8q24.3) / DGKG (3q27.2)GRINA (8q24.3) / GRINA (8q24.3)
GRINA (8q24.3) / MRPL14 (6p21.1)GRINA (8q24.3) / MUC6 (11p15.5)GRINA (8q24.3) / SEPW1 (19q13.33)
GRINA (8q24.3) / SNX14 (6q14.3)GRINA 8q24.3 / MUC6 11p15.5

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GRINA   4589
Cards
Entrez_Gene (NCBI)GRINA  2907  glutamate ionotropic receptor NMDA type subunit associated protein 1
AliasesHNRGW; LFG1; NMDARA1; TMBIM3
GeneCards (Weizmann)GRINA
Ensembl hg19 (Hinxton)ENSG00000178719 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000178719 [Gene_View]  chr8:143990058-143993415 [Contig_View]  GRINA [Vega]
ICGC DataPortalENSG00000178719
TCGA cBioPortalGRINA
AceView (NCBI)GRINA
Genatlas (Paris)GRINA
WikiGenes2907
SOURCE (Princeton)GRINA
Genetics Home Reference (NIH)GRINA
Genomic and cartography
GoldenPath hg38 (UCSC)GRINA  -     chr8:143990058-143993415 +  8q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GRINA  -     8q24.3   [Description]    (hg19-Feb_2009)
EnsemblGRINA - 8q24.3 [CytoView hg19]  GRINA - 8q24.3 [CytoView hg38]
Mapping of homologs : NCBIGRINA [Mapview hg19]  GRINA [Mapview hg38]
OMIM138251   
Gene and transcription
Genbank (Entrez)AB097026 AK127640 AK294127 AL157442 BC041788
RefSeq transcript (Entrez)NM_000837 NM_001009184
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GRINA
Cluster EST : UnigeneHs.594634 [ NCBI ]
CGAP (NCI)Hs.594634
Alternative Splicing GalleryENSG00000178719
Gene ExpressionGRINA [ NCBI-GEO ]   GRINA [ EBI - ARRAY_EXPRESS ]   GRINA [ SEEK ]   GRINA [ MEM ]
Gene Expression Viewer (FireBrowse)GRINA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2907
GTEX Portal (Tissue expression)GRINA
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z429   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z429  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z429
Splice isoforms : SwissVarQ7Z429
PhosPhoSitePlusQ7Z429
Domains : Interpro (EBI)Bax_inhibitor_1-related   
Domain families : Pfam (Sanger)Bax1-I (PF01027)   
Domain families : Pfam (NCBI)pfam01027   
Conserved Domain (NCBI)GRINA
DMDM Disease mutations2907
Blocks (Seattle)GRINA
SuperfamilyQ7Z429
Human Protein AtlasENSG00000178719
Peptide AtlasQ7Z429
HPRD15927
IPIIPI00292999   IPI01012551   IPI00979047   IPI00982724   IPI00978438   IPI00979836   IPI00980412   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z429
IntAct (EBI)Q7Z429
FunCoupENSG00000178719
BioGRIDGRINA
STRING (EMBL)GRINA
ZODIACGRINA
Ontologies - Pathways
QuickGOQ7Z429
Ontology : AmiGOendoplasmic reticulum  Golgi apparatus  integral component of membrane  endoplasmic reticulum calcium ion homeostasis  ion channel binding  negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway  
Ontology : EGO-EBIendoplasmic reticulum  Golgi apparatus  integral component of membrane  endoplasmic reticulum calcium ion homeostasis  ion channel binding  negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway  
NDEx NetworkGRINA
Atlas of Cancer Signalling NetworkGRINA
Wikipedia pathwaysGRINA
Orthology - Evolution
OrthoDB2907
GeneTree (enSembl)ENSG00000178719
Phylogenetic Trees/Animal Genes : TreeFamGRINA
HOVERGENQ7Z429
HOGENOMQ7Z429
Homologs : HomoloGeneGRINA
Homology/Alignments : Family Browser (UCSC)GRINA
Gene fusions - Rearrangements
Fusion : MitelmanGRINA/MUC6 [8q24.3/11p15.5]  
Fusion: TCGAGRINA 8q24.3 MUC6 11p15.5 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGRINA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GRINA
dbVarGRINA
ClinVarGRINA
1000_GenomesGRINA 
Exome Variant ServerGRINA
ExAC (Exome Aggregation Consortium)GRINA (select the gene name)
Genetic variants : HAPMAP2907
Genomic Variants (DGV)GRINA [DGVbeta]
DECIPHERGRINA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGRINA 
Mutations
ICGC Data PortalGRINA 
TCGA Data PortalGRINA 
Broad Tumor PortalGRINA
OASIS PortalGRINA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGRINA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGRINA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GRINA
DgiDB (Drug Gene Interaction Database)GRINA
DoCM (Curated mutations)GRINA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GRINA (select a term)
intoGenGRINA
Cancer3DGRINA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM138251   
Orphanet
MedgenGRINA
Genetic Testing Registry GRINA
NextProtQ7Z429 [Medical]
TSGene2907
GENETestsGRINA
Target ValidationGRINA
Huge Navigator GRINA [HugePedia]
snp3D : Map Gene to Disease2907
BioCentury BCIQGRINA
ClinGenGRINA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2907
Chemical/Pharm GKB GenePA28985
Clinical trialGRINA
Miscellaneous
canSAR (ICR)GRINA (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGRINA
EVEXGRINA
GoPubMedGRINA
iHOPGRINA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:36:01 CEST 2017

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