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GRIP1 (glutamate receptor interacting protein 1)

Identity

Alias (NCBI)FRASRS3
GRIP
HGNC (Hugo) GRIP1
LocusID (NCBI) 23426
Atlas_Id 40754
Location 12q14.3  [Link to chromosome band 12q14]
Location_base_pair Starts at 66347431 and ends at 66679076 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ATF1 (12q13.12) / GRIP1 (12q14.3)FRS2 (12q15) / GRIP1 (12q14.3)GRIP1 (12q14.3) / CASK (Xp11.4)
GRIP1 (12q14.3) / TBL1XR1 (3q26.32)GRIP1 (12q14.3) / TNIP1 (5q33.1)KDM2A (11q13.2) / GRIP1 (12q14.3)
SLC22A23 (6p25.2) / GRIP1 (12q14.3)SOX4 (6p22.3) / GRIP1 (12q14.3)SPTA1 (1q23.1) / GRIP1 (12q14.3)
THAP2 (12q21.1) / GRIP1 (12q14.3)ATF1 12q13.12 / GRIP1 12q14.3FRS2 12q15 / GRIP1 12q14.3
KDM2A 11q13.2 / GRIP1 12q14.3SLC22A23 6p25.2 / GRIP1 12q14.3SPTA1 1q23.1 / GRIP1 12q14.3
THAP2 12q21.1 / GRIP1 12q14.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)GRIP1   18708
Cards
Entrez_Gene (NCBI)GRIP1    glutamate receptor interacting protein 1
AliasesFRASRS3; GRIP
GeneCards (Weizmann)GRIP1
Ensembl hg19 (Hinxton)ENSG00000155974 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000155974 [Gene_View]  ENSG00000155974 [Sequence]  chr12:66347431-66679076 [Contig_View]  GRIP1 [Vega]
ICGC DataPortalENSG00000155974
TCGA cBioPortalGRIP1
AceView (NCBI)GRIP1
Genatlas (Paris)GRIP1
SOURCE (Princeton)GRIP1
Genetics Home Reference (NIH)GRIP1
Genomic and cartography
GoldenPath hg38 (UCSC)GRIP1  -     chr12:66347431-66679076 -  12q14.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GRIP1  -     12q14.3   [Description]    (hg19-Feb_2009)
GoldenPathGRIP1 - 12q14.3 [CytoView hg19]  GRIP1 - 12q14.3 [CytoView hg38]
ImmunoBaseENSG00000155974
Genome Data Viewer NCBIGRIP1 [Mapview hg19]  
OMIM604597   617667   
Gene and transcription
Genbank (Entrez)AI190011 AJ133439 AK095519 AK295565 AK307576
RefSeq transcript (Entrez)NM_001178074 NM_001366722 NM_001366723 NM_001366724 NM_001379345 NM_001379346 NM_001379347 NM_001379348 NM_001379349 NM_001379351 NM_021150
Consensus coding sequences : CCDS (NCBI)GRIP1
Gene ExpressionGRIP1 [ NCBI-GEO ]   GRIP1 [ EBI - ARRAY_EXPRESS ]   GRIP1 [ SEEK ]   GRIP1 [ MEM ]
Gene Expression Viewer (FireBrowse)GRIP1 [ Firebrowse - Broad ]
GenevisibleExpression of GRIP1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23426
GTEX Portal (Tissue expression)GRIP1
Human Protein AtlasENSG00000155974-GRIP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y3R0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y3R0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y3R0
PhosPhoSitePlusQ9Y3R0
Domaine pattern : Prosite (Expaxy)PDZ (PS50106)   
Domains : Interpro (EBI)GRIP1    GRIP1/2    PDZ    PDZ_6    PDZ_sf   
Domain families : Pfam (Sanger)PDZ (PF00595)    PDZ_6 (PF17820)   
Domain families : Pfam (NCBI)pfam00595    pfam17820   
Domain families : Smart (EMBL)PDZ (SM00228)  
Conserved Domain (NCBI)GRIP1
PDB (RSDB)2JIL   
PDB Europe2JIL   
PDB (PDBSum)2JIL   
PDB (IMB)2JIL   
Structural Biology KnowledgeBase2JIL   
SCOP (Structural Classification of Proteins)2JIL   
CATH (Classification of proteins structures)2JIL   
SuperfamilyQ9Y3R0
AlphaFold pdb e-kbQ9Y3R0   
Human Protein Atlas [tissue]ENSG00000155974-GRIP1 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q9Y3R0
IntAct (EBI)Q9Y3R0
BioGRIDGRIP1
STRING (EMBL)GRIP1
ZODIACGRIP1
Ontologies - Pathways
QuickGOQ9Y3R0
Ontology : AmiGOprotein binding  endoplasmic reticulum membrane  cytosol  plasma membrane  plasma membrane  beta-catenin binding  protein C-terminus binding  postsynaptic density  dendrite development  signaling receptor complex adaptor activity  dendrite  cytoplasmic vesicle  glucocorticoid receptor binding  glucocorticoid receptor binding  intracellular signal transduction  neuron projection  perikaryon  membrane raft  postsynaptic membrane  neurotransmitter receptor transport, endosome to postsynaptic membrane  glutamatergic synapse  vesicle-mediated transport in synapse  positive regulation of neuron projection arborization  
Ontology : EGO-EBIprotein binding  endoplasmic reticulum membrane  cytosol  plasma membrane  plasma membrane  beta-catenin binding  protein C-terminus binding  postsynaptic density  dendrite development  signaling receptor complex adaptor activity  dendrite  cytoplasmic vesicle  glucocorticoid receptor binding  glucocorticoid receptor binding  intracellular signal transduction  neuron projection  perikaryon  membrane raft  postsynaptic membrane  neurotransmitter receptor transport, endosome to postsynaptic membrane  glutamatergic synapse  vesicle-mediated transport in synapse  positive regulation of neuron projection arborization  
Pathways : BIOCARTARole of ERBB2 in Signal Transduction and Oncology [Genes]    CARM1 and Regulation of the Estrogen Receptor [Genes]   
NDEx NetworkGRIP1
Atlas of Cancer Signalling NetworkGRIP1
Wikipedia pathwaysGRIP1
Orthology - Evolution
OrthoDB23426
GeneTree (enSembl)ENSG00000155974
Phylogenetic Trees/Animal Genes : TreeFamGRIP1
Homologs : HomoloGeneGRIP1
Homology/Alignments : Family Browser (UCSC)GRIP1
Gene fusions - Rearrangements
Fusion : MitelmanATF1/GRIP1 [12q13.12/12q14.3]  
Fusion : MitelmanFRS2/GRIP1 [12q15/12q14.3]  
Fusion : MitelmanGRIP1/TNIP1 [12q14.3/5q33.1]  
Fusion : MitelmanKDM2A/GRIP1 [11q13.2/12q14.3]  
Fusion : MitelmanSLC22A23/GRIP1 [6p25.2/12q14.3]  
Fusion : MitelmanSPTA1/GRIP1 [1q23.1/12q14.3]  
Fusion : MitelmanTHAP2/GRIP1 [12q21.1/12q14.3]  
Fusion : QuiverGRIP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGRIP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GRIP1
dbVarGRIP1
ClinVarGRIP1
MonarchGRIP1
1000_GenomesGRIP1 
Exome Variant ServerGRIP1
GNOMAD BrowserENSG00000155974
Varsome BrowserGRIP1
ACMGGRIP1 variants
VarityQ9Y3R0
Genomic Variants (DGV)GRIP1 [DGVbeta]
DECIPHERGRIP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGRIP1 
Mutations
ICGC Data PortalGRIP1 
TCGA Data PortalGRIP1 
Broad Tumor PortalGRIP1
OASIS PortalGRIP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGRIP1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGRIP1
Mutations and Diseases : HGMDGRIP1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGRIP1
DgiDB (Drug Gene Interaction Database)GRIP1
DoCM (Curated mutations)GRIP1
CIViC (Clinical Interpretations of Variants in Cancer)GRIP1
Cancer3DGRIP1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604597    617667   
Orphanet1046   
DisGeNETGRIP1
MedgenGRIP1
Genetic Testing Registry GRIP1
NextProtQ9Y3R0 [Medical]
GENETestsGRIP1
Target ValidationGRIP1
Huge Navigator GRIP1 [HugePedia]
ClinGenGRIP1 (curated)
Clinical trials, drugs, therapy
MyCancerGenomeGRIP1
Protein Interactions : CTDGRIP1
Pharm GKB GenePA38652
PharosQ9Y3R0
Clinical trialGRIP1
Miscellaneous
canSAR (ICR)GRIP1
HarmonizomeGRIP1
DataMed IndexGRIP1
Probes
Litterature
PubMed76 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGRIP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:11:32 CEST 2021

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