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GRK7 (G protein-coupled receptor kinase 7)

Identity

Alias_namesGPRK7
Other alias
HGNC (Hugo) GRK7
LocusID (NCBI) 131890
Atlas_Id 64049
Location 3q23  [Link to chromosome band 3q23]
Location_base_pair Starts at 141778201 and ends at 141817050 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GRK7   17031
Cards
Entrez_Gene (NCBI)GRK7  131890  G protein-coupled receptor kinase 7
AliasesGPRK7
GeneCards (Weizmann)GRK7
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr3:141778201-141817050 [Contig_View]  GRK7 [Vega]
TCGA cBioPortalGRK7
AceView (NCBI)GRK7
Genatlas (Paris)GRK7
WikiGenes131890
SOURCE (Princeton)GRK7
Genetics Home Reference (NIH)GRK7
Genomic and cartography
GoldenPath hg38 (UCSC)GRK7  -     chr3:141778201-141817050 +  3q23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GRK7  -     3q23   [Description]    (hg19-Feb_2009)
EnsemblGRK7 - 3q23 [CytoView hg19]  GRK7 - 3q23 [CytoView hg38]
Mapping of homologs : NCBIGRK7 [Mapview hg19]  GRK7 [Mapview hg38]
OMIM606987   
Gene and transcription
Genbank (Entrez)AF282269 AF439409 BC148327 BC152977 DQ426875
RefSeq transcript (Entrez)NM_139209
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GRK7
Cluster EST : UnigeneHs.680654 [ NCBI ]
CGAP (NCI)Hs.680654
Gene ExpressionGRK7 [ NCBI-GEO ]   GRK7 [ EBI - ARRAY_EXPRESS ]   GRK7 [ SEEK ]   GRK7 [ MEM ]
Gene Expression Viewer (FireBrowse)GRK7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)131890
GTEX Portal (Tissue expression)GRK7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WTQ7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WTQ7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WTQ7
Splice isoforms : SwissVarQ8WTQ7
PhosPhoSitePlusQ8WTQ7
Domaine pattern : Prosite (Expaxy)AGC_KINASE_CTER (PS51285)    PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)    RGS (PS50132)   
Domains : Interpro (EBI)AGC-kinase_C    GPCR_kinase    Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    RGS    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)    RGS (PF00615)   
Domain families : Pfam (NCBI)pfam00069    pfam00615   
Domain families : Smart (EMBL)RGS (SM00315)  S_TK_X (SM00133)  S_TKc (SM00220)  
Conserved Domain (NCBI)GRK7
DMDM Disease mutations131890
Blocks (Seattle)GRK7
SuperfamilyQ8WTQ7
Peptide AtlasQ8WTQ7
HPRD07378
IPIIPI00102804   
Protein Interaction databases
DIP (DOE-UCLA)Q8WTQ7
IntAct (EBI)Q8WTQ7
BioGRIDGRK7
STRING (EMBL)GRK7
ZODIACGRK7
Ontologies - Pathways
QuickGOQ8WTQ7
Ontology : AmiGOG-protein coupled receptor kinase activity  ATP binding  signal transduction  visual perception  regulation of rhodopsin mediated signaling pathway  protein autophosphorylation  rhodopsin kinase activity  rhodopsin kinase activity  photoreceptor disc membrane  
Ontology : EGO-EBIG-protein coupled receptor kinase activity  ATP binding  signal transduction  visual perception  regulation of rhodopsin mediated signaling pathway  protein autophosphorylation  rhodopsin kinase activity  rhodopsin kinase activity  photoreceptor disc membrane  
Pathways : KEGGChemokine signaling pathway    Endocytosis    Phototransduction   
NDEx NetworkGRK7
Atlas of Cancer Signalling NetworkGRK7
Wikipedia pathwaysGRK7
Orthology - Evolution
OrthoDB131890
Phylogenetic Trees/Animal Genes : TreeFamGRK7
HOVERGENQ8WTQ7
HOGENOMQ8WTQ7
Homologs : HomoloGeneGRK7
Homology/Alignments : Family Browser (UCSC)GRK7
Gene fusions - Rearrangements
Tumor Fusion PortalGRK7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGRK7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GRK7
dbVarGRK7
ClinVarGRK7
1000_GenomesGRK7 
Exome Variant ServerGRK7
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP131890
Genomic Variants (DGV)GRK7 [DGVbeta]
DECIPHERGRK7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGRK7 
Mutations
ICGC Data PortalGRK7 
TCGA Data PortalGRK7 
Broad Tumor PortalGRK7
OASIS PortalGRK7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGRK7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGRK7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GRK7
DgiDB (Drug Gene Interaction Database)GRK7
DoCM (Curated mutations)GRK7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GRK7 (select a term)
intoGenGRK7
Cancer3DGRK7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606987   
Orphanet
DisGeNETGRK7
MedgenGRK7
Genetic Testing Registry GRK7
NextProtQ8WTQ7 [Medical]
TSGene131890
GENETestsGRK7
Target ValidationGRK7
Huge Navigator GRK7 [HugePedia]
snp3D : Map Gene to Disease131890
BioCentury BCIQGRK7
ClinGenGRK7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD131890
Chemical/Pharm GKB GenePA38433
Clinical trialGRK7
Miscellaneous
canSAR (ICR)GRK7 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGRK7
EVEXGRK7
GoPubMedGRK7
iHOPGRK7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:07:34 CET 2017

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