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GRP (gastrin releasing peptide)

Identity

Alias_namesgastrin-releasing peptide
Other aliasBN
GRP-10
preproGRP
proGRP
HGNC (Hugo) GRP
LocusID (NCBI) 2922
Atlas_Id 40758
Location 18q21.32  [Link to chromosome band 18q21]
Location_base_pair Starts at 59220168 and ends at 59230774 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GRP   4605
Cards
Entrez_Gene (NCBI)GRP  2922  gastrin releasing peptide
AliasesBN; GRP-10; preproGRP; proGRP
GeneCards (Weizmann)GRP
Ensembl hg19 (Hinxton)ENSG00000134443 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134443 [Gene_View]  chr18:59220168-59230774 [Contig_View]  GRP [Vega]
ICGC DataPortalENSG00000134443
TCGA cBioPortalGRP
AceView (NCBI)GRP
Genatlas (Paris)GRP
WikiGenes2922
SOURCE (Princeton)GRP
Genetics Home Reference (NIH)GRP
Genomic and cartography
GoldenPath hg38 (UCSC)GRP  -     chr18:59220168-59230774 +  18q21.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GRP  -     18q21.32   [Description]    (hg19-Feb_2009)
EnsemblGRP - 18q21.32 [CytoView hg19]  GRP - 18q21.32 [CytoView hg38]
Mapping of homologs : NCBIGRP [Mapview hg19]  GRP [Mapview hg38]
OMIM137260   
Gene and transcription
Genbank (Entrez)AA989236 AB102889 AK307264 BC004488 BT006803
RefSeq transcript (Entrez)NM_001012512 NM_001012513 NM_002091
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GRP
Cluster EST : UnigeneHs.153444 [ NCBI ]
CGAP (NCI)Hs.153444
Alternative Splicing GalleryENSG00000134443
Gene ExpressionGRP [ NCBI-GEO ]   GRP [ EBI - ARRAY_EXPRESS ]   GRP [ SEEK ]   GRP [ MEM ]
Gene Expression Viewer (FireBrowse)GRP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2922
GTEX Portal (Tissue expression)GRP
Human Protein AtlasENSG00000134443-GRP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07492   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP07492  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP07492
Splice isoforms : SwissVarP07492
PhosPhoSitePlusP07492
Domaine pattern : Prosite (Expaxy)BOMBESIN (PS00257)   
Domains : Interpro (EBI)Bombesin    Gastrin-RP   
Domain families : Pfam (Sanger)Bombesin (PF02044)   
Domain families : Pfam (NCBI)pfam02044   
Conserved Domain (NCBI)GRP
DMDM Disease mutations2922
Blocks (Seattle)GRP
PDB (SRS)2N0B    2N0C    2N0D    2N0E    2N0F    2N0G    2N0H   
PDB (PDBSum)2N0B    2N0C    2N0D    2N0E    2N0F    2N0G    2N0H   
PDB (IMB)2N0B    2N0C    2N0D    2N0E    2N0F    2N0G    2N0H   
PDB (RSDB)2N0B    2N0C    2N0D    2N0E    2N0F    2N0G    2N0H   
Structural Biology KnowledgeBase2N0B    2N0C    2N0D    2N0E    2N0F    2N0G    2N0H   
SCOP (Structural Classification of Proteins)2N0B    2N0C    2N0D    2N0E    2N0F    2N0G    2N0H   
CATH (Classification of proteins structures)2N0B    2N0C    2N0D    2N0E    2N0F    2N0G    2N0H   
SuperfamilyP07492
Human Protein Atlas [tissue]ENSG00000134443-GRP [tissue]
Peptide AtlasP07492
HPRD08845
IPIIPI00011722   IPI00218671   IPI00218672   IPI00974355   IPI00980093   
Protein Interaction databases
DIP (DOE-UCLA)P07492
IntAct (EBI)P07492
FunCoupENSG00000134443
BioGRIDGRP
STRING (EMBL)GRP
ZODIACGRP
Ontologies - Pathways
QuickGOP07492
Ontology : AmiGOreceptor binding  neuropeptide hormone activity  extracellular region  extracellular space  signal transduction  G-protein coupled receptor signaling pathway  neuropeptide signaling pathway  regulation of receptor activity  secretory granule lumen  social behavior  psychomotor behavior  response to external biotic stimulus  positive regulation of peptide hormone secretion  positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway  
Ontology : EGO-EBIreceptor binding  neuropeptide hormone activity  extracellular region  extracellular space  signal transduction  G-protein coupled receptor signaling pathway  neuropeptide signaling pathway  regulation of receptor activity  secretory granule lumen  social behavior  psychomotor behavior  response to external biotic stimulus  positive regulation of peptide hormone secretion  positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkGRP
Atlas of Cancer Signalling NetworkGRP
Wikipedia pathwaysGRP
Orthology - Evolution
OrthoDB2922
GeneTree (enSembl)ENSG00000134443
Phylogenetic Trees/Animal Genes : TreeFamGRP
HOVERGENP07492
HOGENOMP07492
Homologs : HomoloGeneGRP
Homology/Alignments : Family Browser (UCSC)GRP
Gene fusions - Rearrangements
Fusion : QuiverGRP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGRP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GRP
dbVarGRP
ClinVarGRP
1000_GenomesGRP 
Exome Variant ServerGRP
ExAC (Exome Aggregation Consortium)ENSG00000134443
GNOMAD BrowserENSG00000134443
Genetic variants : HAPMAP2922
Genomic Variants (DGV)GRP [DGVbeta]
DECIPHERGRP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGRP 
Mutations
ICGC Data PortalGRP 
TCGA Data PortalGRP 
Broad Tumor PortalGRP
OASIS PortalGRP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGRP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGRP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GRP
DgiDB (Drug Gene Interaction Database)GRP
DoCM (Curated mutations)GRP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GRP (select a term)
intoGenGRP
Cancer3DGRP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM137260   
Orphanet
DisGeNETGRP
MedgenGRP
Genetic Testing Registry GRP
NextProtP07492 [Medical]
TSGene2922
GENETestsGRP
Target ValidationGRP
Huge Navigator GRP [HugePedia]
snp3D : Map Gene to Disease2922
BioCentury BCIQGRP
ClinGenGRP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2922
Chemical/Pharm GKB GenePA28999
Clinical trialGRP
Miscellaneous
canSAR (ICR)GRP (select the gene name)
Probes
Litterature
PubMed71 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGRP
EVEXGRP
GoPubMedGRP
iHOPGRP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Feb 28 13:15:12 CET 2018
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