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GRP (gastrin releasing peptide)

Identity

Alias (NCBI)BN
GRP-10
preproGRP
proGRP
HGNC (Hugo) GRP
HGNC Alias namebombesin
 neuromedin C
 prepro-GRP
HGNC Previous namegastrin-releasing peptide
LocusID (NCBI) 2922
Atlas_Id 40758
Location 18q21.32  [Link to chromosome band 18q21]
Location_base_pair Starts at 59220158 and ends at 59230770 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

 

Nomenclature
HGNC (Hugo)GRP   4605
Cards
Entrez_Gene (NCBI)GRP    gastrin releasing peptide
AliasesBN; GRP-10; preproGRP; proGRP
GeneCards (Weizmann)GRP
Ensembl hg19 (Hinxton)ENSG00000134443 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134443 [Gene_View]  ENSG00000134443 [Sequence]  chr18:59220158-59230770 [Contig_View]  GRP [Vega]
ICGC DataPortalENSG00000134443
TCGA cBioPortalGRP
AceView (NCBI)GRP
Genatlas (Paris)GRP
SOURCE (Princeton)GRP
Genetics Home Reference (NIH)GRP
Genomic and cartography
GoldenPath hg38 (UCSC)GRP  -     chr18:59220158-59230770 +  18q21.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GRP  -     18q21.32   [Description]    (hg19-Feb_2009)
GoldenPathGRP - 18q21.32 [CytoView hg19]  GRP - 18q21.32 [CytoView hg38]
ImmunoBaseENSG00000134443
Genome Data Viewer NCBIGRP [Mapview hg19]  
OMIM137260   
Gene and transcription
Genbank (Entrez)AA989236 AB102889 AK307264 BC004488 BT006803
RefSeq transcript (Entrez)NM_001012512 NM_001012513 NM_002091
Consensus coding sequences : CCDS (NCBI)GRP
Gene ExpressionGRP [ NCBI-GEO ]   GRP [ EBI - ARRAY_EXPRESS ]   GRP [ SEEK ]   GRP [ MEM ]
Gene Expression Viewer (FireBrowse)GRP [ Firebrowse - Broad ]
GenevisibleExpression of GRP in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2922
GTEX Portal (Tissue expression)GRP
Human Protein AtlasENSG00000134443-GRP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07492   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP07492  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP07492
PhosPhoSitePlusP07492
Domaine pattern : Prosite (Expaxy)BOMBESIN (PS00257)   
Domains : Interpro (EBI)Bombesin    Gastrin-RP   
Domain families : Pfam (Sanger)Bombesin (PF02044)   
Domain families : Pfam (NCBI)pfam02044   
Conserved Domain (NCBI)GRP
PDB (RSDB)2N0B    2N0C    2N0D    2N0E    2N0F    2N0G    2N0H   
PDB Europe2N0B    2N0C    2N0D    2N0E    2N0F    2N0G    2N0H   
PDB (PDBSum)2N0B    2N0C    2N0D    2N0E    2N0F    2N0G    2N0H   
PDB (IMB)2N0B    2N0C    2N0D    2N0E    2N0F    2N0G    2N0H   
Structural Biology KnowledgeBase2N0B    2N0C    2N0D    2N0E    2N0F    2N0G    2N0H   
SCOP (Structural Classification of Proteins)2N0B    2N0C    2N0D    2N0E    2N0F    2N0G    2N0H   
CATH (Classification of proteins structures)2N0B    2N0C    2N0D    2N0E    2N0F    2N0G    2N0H   
SuperfamilyP07492
AlphaFold pdb e-kbP07492   
Human Protein Atlas [tissue]ENSG00000134443-GRP [tissue]
HPRD08845
Protein Interaction databases
DIP (DOE-UCLA)P07492
IntAct (EBI)P07492
BioGRIDGRP
STRING (EMBL)GRP
ZODIACGRP
Ontologies - Pathways
QuickGOP07492
Ontology : AmiGOsignaling receptor binding  neuropeptide hormone activity  neuropeptide hormone activity  protein binding  extracellular region  extracellular space  extracellular space  signal transduction  neuropeptide signaling pathway  neuropeptide signaling pathway  secretory granule lumen  social behavior  psychomotor behavior  response to external biotic stimulus  positive regulation of peptide hormone secretion  positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway  
Ontology : EGO-EBIsignaling receptor binding  neuropeptide hormone activity  neuropeptide hormone activity  protein binding  extracellular region  extracellular space  extracellular space  signal transduction  neuropeptide signaling pathway  neuropeptide signaling pathway  secretory granule lumen  social behavior  psychomotor behavior  response to external biotic stimulus  positive regulation of peptide hormone secretion  positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway  
NDEx NetworkGRP
Atlas of Cancer Signalling NetworkGRP
Wikipedia pathwaysGRP
Orthology - Evolution
OrthoDB2922
GeneTree (enSembl)ENSG00000134443
Phylogenetic Trees/Animal Genes : TreeFamGRP
Homologs : HomoloGeneGRP
Homology/Alignments : Family Browser (UCSC)GRP
Gene fusions - Rearrangements
Fusion : QuiverGRP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGRP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GRP
dbVarGRP
ClinVarGRP
MonarchGRP
1000_GenomesGRP 
Exome Variant ServerGRP
GNOMAD BrowserENSG00000134443
Varsome BrowserGRP
ACMGGRP variants
VarityP07492
Genomic Variants (DGV)GRP [DGVbeta]
DECIPHERGRP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGRP 
Mutations
ICGC Data PortalGRP 
TCGA Data PortalGRP 
Broad Tumor PortalGRP
OASIS PortalGRP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGRP  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGRP
Mutations and Diseases : HGMDGRP
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGRP
DgiDB (Drug Gene Interaction Database)GRP
DoCM (Curated mutations)GRP
CIViC (Clinical Interpretations of Variants in Cancer)GRP
Cancer3DGRP
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM137260   
Orphanet
DisGeNETGRP
MedgenGRP
Genetic Testing Registry GRP
NextProtP07492 [Medical]
GENETestsGRP
Target ValidationGRP
Huge Navigator GRP [HugePedia]
ClinGenGRP
Clinical trials, drugs, therapy
MyCancerGenomeGRP
Protein Interactions : CTDGRP
Pharm GKB GenePA28999
PharosP07492
Clinical trialGRP
Miscellaneous
canSAR (ICR)GRP
HarmonizomeGRP
ARCHS4GRP
DataMed IndexGRP
Probes
Litterature
PubMed91 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGRP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 12:36:01 CET 2022
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