Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GRXCR2 (glutaredoxin and cysteine rich domain containing 2)

Identity

Alias_namesglutaredoxin, cysteine rich 2
Alias_symbol (synonym)DFNB101
Other alias
HGNC (Hugo) GRXCR2
LocusID (NCBI) 643226
Atlas_Id 64064
Location 5q32  [Link to chromosome band 5q32]
Location_base_pair Starts at 145859733 and ends at 145872968 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GRXCR2   33862
Cards
Entrez_Gene (NCBI)GRXCR2  643226  glutaredoxin and cysteine rich domain containing 2
AliasesDFNB101
GeneCards (Weizmann)GRXCR2
Ensembl hg19 (Hinxton)ENSG00000204928 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204928 [Gene_View]  chr5:145859733-145872968 [Contig_View]  GRXCR2 [Vega]
ICGC DataPortalENSG00000204928
TCGA cBioPortalGRXCR2
AceView (NCBI)GRXCR2
Genatlas (Paris)GRXCR2
WikiGenes643226
SOURCE (Princeton)GRXCR2
Genetics Home Reference (NIH)GRXCR2
Genomic and cartography
GoldenPath hg38 (UCSC)GRXCR2  -     chr5:145859733-145872968 -  5q32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GRXCR2  -     5q32   [Description]    (hg19-Feb_2009)
EnsemblGRXCR2 - 5q32 [CytoView hg19]  GRXCR2 - 5q32 [CytoView hg38]
Mapping of homologs : NCBIGRXCR2 [Mapview hg19]  GRXCR2 [Mapview hg38]
OMIM615762   615837   
Gene and transcription
Genbank (Entrez)DN831963
RefSeq transcript (Entrez)NM_001080516
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GRXCR2
Cluster EST : UnigeneHs.570895 [ NCBI ]
CGAP (NCI)Hs.570895
Alternative Splicing GalleryENSG00000204928
Gene ExpressionGRXCR2 [ NCBI-GEO ]   GRXCR2 [ EBI - ARRAY_EXPRESS ]   GRXCR2 [ SEEK ]   GRXCR2 [ MEM ]
Gene Expression Viewer (FireBrowse)GRXCR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)643226
GTEX Portal (Tissue expression)GRXCR2
Human Protein AtlasENSG00000204928-GRXCR2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA6NFK2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA6NFK2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA6NFK2
Splice isoforms : SwissVarA6NFK2
PhosPhoSitePlusA6NFK2
Domains : Interpro (EBI)GRXCR2    HSP_DnaJ_Cys-rich_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)GRXCR2
DMDM Disease mutations643226
Blocks (Seattle)GRXCR2
SuperfamilyA6NFK2
Human Protein Atlas [tissue]ENSG00000204928-GRXCR2 [tissue]
Peptide AtlasA6NFK2
IPIIPI00740470   
Protein Interaction databases
DIP (DOE-UCLA)A6NFK2
IntAct (EBI)A6NFK2
FunCoupENSG00000204928
BioGRIDGRXCR2
STRING (EMBL)GRXCR2
ZODIACGRXCR2
Ontologies - Pathways
QuickGOA6NFK2
Ontology : AmiGOmicrovillus  sensory perception of sound  heat shock protein binding  stereocilium  unfolded protein binding  
Ontology : EGO-EBImicrovillus  sensory perception of sound  heat shock protein binding  stereocilium  unfolded protein binding  
NDEx NetworkGRXCR2
Atlas of Cancer Signalling NetworkGRXCR2
Wikipedia pathwaysGRXCR2
Orthology - Evolution
OrthoDB643226
GeneTree (enSembl)ENSG00000204928
Phylogenetic Trees/Animal Genes : TreeFamGRXCR2
HOVERGENA6NFK2
HOGENOMA6NFK2
Homologs : HomoloGeneGRXCR2
Homology/Alignments : Family Browser (UCSC)GRXCR2
Gene fusions - Rearrangements
Tumor Fusion PortalGRXCR2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGRXCR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GRXCR2
dbVarGRXCR2
ClinVarGRXCR2
1000_GenomesGRXCR2 
Exome Variant ServerGRXCR2
ExAC (Exome Aggregation Consortium)ENSG00000204928
GNOMAD BrowserENSG00000204928
Genetic variants : HAPMAP643226
Genomic Variants (DGV)GRXCR2 [DGVbeta]
DECIPHERGRXCR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGRXCR2 
Mutations
ICGC Data PortalGRXCR2 
TCGA Data PortalGRXCR2 
Broad Tumor PortalGRXCR2
OASIS PortalGRXCR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGRXCR2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGRXCR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GRXCR2
DgiDB (Drug Gene Interaction Database)GRXCR2
DoCM (Curated mutations)GRXCR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GRXCR2 (select a term)
intoGenGRXCR2
Cancer3DGRXCR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615762    615837   
Orphanet12047   
DisGeNETGRXCR2
MedgenGRXCR2
Genetic Testing Registry GRXCR2
NextProtA6NFK2 [Medical]
TSGene643226
GENETestsGRXCR2
Target ValidationGRXCR2
Huge Navigator GRXCR2 [HugePedia]
snp3D : Map Gene to Disease643226
BioCentury BCIQGRXCR2
ClinGenGRXCR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD643226
Chemical/Pharm GKB GenePA164720311
Clinical trialGRXCR2
Miscellaneous
canSAR (ICR)GRXCR2 (select the gene name)
Probes
Litterature
PubMed2 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGRXCR2
EVEXGRXCR2
GoPubMedGRXCR2
iHOPGRXCR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:11:46 CET 2017

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