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GSAP (gamma-secretase activating protein)

Identity

Alias_namesPION
pigeon homolog (Drosophila)
Alias_symbol (synonym)LOC54103
Other alias
HGNC (Hugo) GSAP
LocusID (NCBI) 54103
Atlas_Id 64070
Location 7q11.23  [Link to chromosome band 7q11]
Location_base_pair Starts at 77310751 and ends at 77416400 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GSAP (7q11.23) / GSAP (7q11.23)GSAP (7q11.23) / STYXL1 (7q11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GSAP   28042
Cards
Entrez_Gene (NCBI)GSAP  54103  gamma-secretase activating protein
AliasesPION
GeneCards (Weizmann)GSAP
Ensembl hg19 (Hinxton)ENSG00000186088 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186088 [Gene_View]  chr7:77310751-77416400 [Contig_View]  GSAP [Vega]
ICGC DataPortalENSG00000186088
TCGA cBioPortalGSAP
AceView (NCBI)GSAP
Genatlas (Paris)GSAP
WikiGenes54103
SOURCE (Princeton)GSAP
Genetics Home Reference (NIH)GSAP
Genomic and cartography
GoldenPath hg38 (UCSC)GSAP  -     chr7:77310751-77416400 -  7q11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GSAP  -     7q11.23   [Description]    (hg19-Feb_2009)
EnsemblGSAP - 7q11.23 [CytoView hg19]  GSAP - 7q11.23 [CytoView hg38]
Mapping of homologs : NCBIGSAP [Mapview hg19]  GSAP [Mapview hg38]
OMIM613552   
Gene and transcription
Genbank (Entrez)AK026696 AK026747 AK027188 AK126364 AL079277
RefSeq transcript (Entrez)NM_001350896 NM_001350897 NM_001350898 NM_001350899 NM_001350900 NM_001350901 NM_017439
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GSAP
Cluster EST : UnigeneHs.186649 [ NCBI ]
CGAP (NCI)Hs.186649
Alternative Splicing GalleryENSG00000186088
Gene ExpressionGSAP [ NCBI-GEO ]   GSAP [ EBI - ARRAY_EXPRESS ]   GSAP [ SEEK ]   GSAP [ MEM ]
Gene Expression Viewer (FireBrowse)GSAP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54103
GTEX Portal (Tissue expression)GSAP
Protein : pattern, domain, 3D structure
UniProt/SwissProtA4D1B5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA4D1B5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA4D1B5
Splice isoforms : SwissVarA4D1B5
PhosPhoSitePlusA4D1B5
Domains : Interpro (EBI)GSAP_C_dom    GSAP_fam   
Domain families : Pfam (Sanger)GSAP-16 (PF14959)   
Domain families : Pfam (NCBI)pfam14959   
Conserved Domain (NCBI)GSAP
DMDM Disease mutations54103
Blocks (Seattle)GSAP
SuperfamilyA4D1B5
Human Protein AtlasENSG00000186088
Peptide AtlasA4D1B5
HPRD18671
IPIIPI00893006   IPI00894268   IPI00871629   IPI01013779   IPI00397540   IPI01014424   IPI00925142   IPI00927171   
Protein Interaction databases
DIP (DOE-UCLA)A4D1B5
IntAct (EBI)A4D1B5
FunCoupENSG00000186088
BioGRIDGSAP
STRING (EMBL)GSAP
ZODIACGSAP
Ontologies - Pathways
QuickGOA4D1B5
Ontology : AmiGObeta-amyloid binding  trans-Golgi network  regulation of proteolysis  positive regulation of beta-amyloid formation  
Ontology : EGO-EBIbeta-amyloid binding  trans-Golgi network  regulation of proteolysis  positive regulation of beta-amyloid formation  
NDEx NetworkGSAP
Atlas of Cancer Signalling NetworkGSAP
Wikipedia pathwaysGSAP
Orthology - Evolution
OrthoDB54103
GeneTree (enSembl)ENSG00000186088
Phylogenetic Trees/Animal Genes : TreeFamGSAP
HOVERGENA4D1B5
HOGENOMA4D1B5
Homologs : HomoloGeneGSAP
Homology/Alignments : Family Browser (UCSC)GSAP
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGSAP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GSAP
dbVarGSAP
ClinVarGSAP
1000_GenomesGSAP 
Exome Variant ServerGSAP
ExAC (Exome Aggregation Consortium)GSAP (select the gene name)
Genetic variants : HAPMAP54103
Genomic Variants (DGV)GSAP [DGVbeta]
DECIPHERGSAP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGSAP 
Mutations
ICGC Data PortalGSAP 
TCGA Data PortalGSAP 
Broad Tumor PortalGSAP
OASIS PortalGSAP [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDGSAP
BioMutasearch GSAP
DgiDB (Drug Gene Interaction Database)GSAP
DoCM (Curated mutations)GSAP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GSAP (select a term)
intoGenGSAP
Cancer3DGSAP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613552   
Orphanet
MedgenGSAP
Genetic Testing Registry GSAP
NextProtA4D1B5 [Medical]
TSGene54103
GENETestsGSAP
Target ValidationGSAP
Huge Navigator GSAP [HugePedia]
snp3D : Map Gene to Disease54103
BioCentury BCIQGSAP
ClinGenGSAP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54103
Chemical/Pharm GKB GenePA164724500
Clinical trialGSAP
Miscellaneous
canSAR (ICR)GSAP (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGSAP
EVEXGSAP
GoPubMedGSAP
iHOPGSAP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:51:35 CEST 2017

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