GSDMC (gasdermin C)

2003-12-01  

Identity

HGNC
LOCATION
8q24.21
LOCUSID
ALIAS
MLZE
FUSION GENES

Other Information

Locus ID:

NCBI: 56169
MIM: 608384
HGNC: 7151
Ensembl: ENSG00000147697

Variants:

dbSNP: 56169
ClinVar: 56169
TCGA: ENSG00000147697
COSMIC: GSDMC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147697ENST00000276708Q9BYG8
ENSG00000147697ENST00000619643Q9BYG8

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
190513102009Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium.40
278356992016Gasdermin C Is Upregulated by Inactivation of Transforming Growth Factor β Receptor Type II in the Presence of Mutated Apc, Promoting Colorectal Cancer Proliferation.8
294288152018Gasdermin C is induced by ultraviolet light and contributes to MMP-1 expression via activation of ERK and JNK pathways.1
302265652018Ultraviolet light-induced gasdermin C expression is mediated via TRPV1/calcium/calcineurin/NFATc1 signaling.0

Citation

Dessen P

GSDMC (gasdermin C)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41384/gsdmc