Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GSG2 (germ cell associated 2, haspin)

Identity

Alias_namesgerm cell associated 2 (haspin)
Alias_symbol (synonym)haspin
Other aliasHASPIN
HGNC (Hugo) GSG2
LocusID (NCBI) 83903
Atlas_Id 43302
Location 17p13.2  [Link to chromosome band 17p13]
Location_base_pair Starts at 3627197 and ends at 3629992 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GSG2   19682
Cards
Entrez_Gene (NCBI)GSG2  83903  germ cell associated 2, haspin
AliasesHASPIN
GeneCards (Weizmann)GSG2
Ensembl hg19 (Hinxton)ENSG00000177602 [Gene_View]  chr17:3627197-3629992 [Contig_View]  GSG2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000177602 [Gene_View]  chr17:3627197-3629992 [Contig_View]  GSG2 [Vega]
ICGC DataPortalENSG00000177602
TCGA cBioPortalGSG2
AceView (NCBI)GSG2
Genatlas (Paris)GSG2
WikiGenes83903
SOURCE (Princeton)GSG2
Genetics Home Reference (NIH)GSG2
Genomic and cartography
GoldenPath hg19 (UCSC)GSG2  -     chr17:3627197-3629992 +  17p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GSG2  -     17p13.2   [Description]    (hg38-Dec_2013)
EnsemblGSG2 - 17p13.2 [CytoView hg19]  GSG2 - 17p13.2 [CytoView hg38]
Mapping of homologs : NCBIGSG2 [Mapview hg19]  GSG2 [Mapview hg38]
OMIM609240   
Gene and transcription
Genbank (Entrez)AB039834 AF289865 AK056691 AK292715 AK310546
RefSeq transcript (Entrez)NM_031965
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010718 NW_004929405
Consensus coding sequences : CCDS (NCBI)GSG2
Cluster EST : UnigeneHs.534059 [ NCBI ]
CGAP (NCI)Hs.534059
Alternative Splicing GalleryENSG00000177602
Gene ExpressionGSG2 [ NCBI-GEO ]   GSG2 [ EBI - ARRAY_EXPRESS ]   GSG2 [ SEEK ]   GSG2 [ MEM ]
Gene Expression Viewer (FireBrowse)GSG2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83903
GTEX Portal (Tissue expression)GSG2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TF76   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TF76  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TF76
Splice isoforms : SwissVarQ8TF76
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.12.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   
PhosPhoSitePlusQ8TF76
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)   
Domains : Interpro (EBI)DUF3635    Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS   
Domain families : Pfam (Sanger)DUF3635 (PF12330)    Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam12330    pfam00069   
Conserved Domain (NCBI)GSG2
DMDM Disease mutations83903
Blocks (Seattle)GSG2
PDB (SRS)2VUW    2WB8    3DLZ    3E7V    3F2N    3FMD    3IQ7    4OUC    4QTC   
PDB (PDBSum)2VUW    2WB8    3DLZ    3E7V    3F2N    3FMD    3IQ7    4OUC    4QTC   
PDB (IMB)2VUW    2WB8    3DLZ    3E7V    3F2N    3FMD    3IQ7    4OUC    4QTC   
PDB (RSDB)2VUW    2WB8    3DLZ    3E7V    3F2N    3FMD    3IQ7    4OUC    4QTC   
Structural Biology KnowledgeBase2VUW    2WB8    3DLZ    3E7V    3F2N    3FMD    3IQ7    4OUC    4QTC   
SCOP (Structural Classification of Proteins)2VUW    2WB8    3DLZ    3E7V    3F2N    3FMD    3IQ7    4OUC    4QTC   
CATH (Classification of proteins structures)2VUW    2WB8    3DLZ    3E7V    3F2N    3FMD    3IQ7    4OUC    4QTC   
SuperfamilyQ8TF76
Human Protein AtlasENSG00000177602
Peptide AtlasQ8TF76
HPRD17083
IPIIPI00397836   IPI00401554   
Protein Interaction databases
DIP (DOE-UCLA)Q8TF76
IntAct (EBI)Q8TF76
FunCoupENSG00000177602
BioGRIDGSG2
STRING (EMBL)GSG2
ZODIACGSG2
Ontologies - Pathways
QuickGOQ8TF76
Ontology : AmiGOprotein kinase activity  protein binding  ATP binding  nucleus  chromosome  cytoplasm  centrosome  spindle  protein phosphorylation  mitotic sister chromatid cohesion  intracellular signal transduction  protein localization to chromosome, centromeric region  histone kinase activity (H3-T3 specific)  regulation of spindle checkpoint  histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore  
Ontology : EGO-EBIprotein kinase activity  protein binding  ATP binding  nucleus  chromosome  cytoplasm  centrosome  spindle  protein phosphorylation  mitotic sister chromatid cohesion  intracellular signal transduction  protein localization to chromosome, centromeric region  histone kinase activity (H3-T3 specific)  regulation of spindle checkpoint  histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore  
NDEx NetworkGSG2
Atlas of Cancer Signalling NetworkGSG2
Wikipedia pathwaysGSG2
Orthology - Evolution
OrthoDB83903
GeneTree (enSembl)ENSG00000177602
Phylogenetic Trees/Animal Genes : TreeFamGSG2
HOVERGENQ8TF76
HOGENOMQ8TF76
Homologs : HomoloGeneGSG2
Homology/Alignments : Family Browser (UCSC)GSG2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGSG2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GSG2
dbVarGSG2
ClinVarGSG2
1000_GenomesGSG2 
Exome Variant ServerGSG2
ExAC (Exome Aggregation Consortium)GSG2 (select the gene name)
Genetic variants : HAPMAP83903
Genomic Variants (DGV)GSG2 [DGVbeta]
DECIPHER (Syndromes)17:3627197-3629992  ENSG00000177602
CONAN: Copy Number AnalysisGSG2 
Mutations
ICGC Data PortalGSG2 
TCGA Data PortalGSG2 
Broad Tumor PortalGSG2
OASIS PortalGSG2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGSG2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGSG2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GSG2
DgiDB (Drug Gene Interaction Database)GSG2
DoCM (Curated mutations)GSG2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GSG2 (select a term)
intoGenGSG2
Cancer3DGSG2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609240   
Orphanet
MedgenGSG2
Genetic Testing Registry GSG2
NextProtQ8TF76 [Medical]
TSGene83903
GENETestsGSG2
Huge Navigator GSG2 [HugePedia]
snp3D : Map Gene to Disease83903
BioCentury BCIQGSG2
ClinGenGSG2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD83903
Chemical/Pharm GKB GenePA134909705
Clinical trialGSG2
Miscellaneous
canSAR (ICR)GSG2 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGSG2
EVEXGSG2
GoPubMedGSG2
iHOPGSG2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:08:17 CET 2017

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