Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GSPT1 (G1 to S phase transition 1)

Identity

Alias (NCBI)551G9.2
ETF3A
GST1
eRF3a
HGNC (Hugo) GSPT1
HGNC Alias symbGST1
ETF3A
eRF3a
HGNC Alias nameeukaryotic release factor 3a
LocusID (NCBI) 2935
Atlas_Id 40762
Location 16p13.13  [Link to chromosome band 16p13]
Location_base_pair Starts at 11868128 and ends at 11915956 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BACH1 (21q21.3) / GSPT1 (16p13.13)GSPT1 (16p13.13) / GSPT1 (16p13.13)GSPT1 (16p13.13) / HPGD (4q34.1)
NSUN3 (3q11.1) / GSPT1 (16p13.13)RBBP5 (1q32.1) / GSPT1 (16p13.13)TXNDC11 (16p13.13) / GSPT1 (16p13.13)
TXNDC11 16p13.13 / GSPT1 16p13.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)GSPT1   4621
Cards
Entrez_Gene (NCBI)GSPT1    G1 to S phase transition 1
Aliases551G9.2; ETF3A; GST1; eRF3a
GeneCards (Weizmann)GSPT1
Ensembl hg19 (Hinxton)ENSG00000103342 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000103342 [Gene_View]  ENSG00000103342 [Sequence]  chr16:11868128-11915956 [Contig_View]  GSPT1 [Vega]
ICGC DataPortalENSG00000103342
TCGA cBioPortalGSPT1
AceView (NCBI)GSPT1
Genatlas (Paris)GSPT1
SOURCE (Princeton)GSPT1
Genetics Home Reference (NIH)GSPT1
Genomic and cartography
GoldenPath hg38 (UCSC)GSPT1  -     chr16:11868128-11915956 -  16p13.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GSPT1  -     16p13.13   [Description]    (hg19-Feb_2009)
GoldenPathGSPT1 - 16p13.13 [CytoView hg19]  GSPT1 - 16p13.13 [CytoView hg38]
ImmunoBaseENSG00000103342
Genome Data Viewer NCBIGSPT1 [Mapview hg19]  
OMIM139259   
Gene and transcription
Genbank (Entrez)AK095367 AK095483 AK096386 AK290382 AK315267
RefSeq transcript (Entrez)NM_001130006 NM_001130007 NM_002094
Consensus coding sequences : CCDS (NCBI)GSPT1
Gene ExpressionGSPT1 [ NCBI-GEO ]   GSPT1 [ EBI - ARRAY_EXPRESS ]   GSPT1 [ SEEK ]   GSPT1 [ MEM ]
Gene Expression Viewer (FireBrowse)GSPT1 [ Firebrowse - Broad ]
GenevisibleExpression of GSPT1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2935
GTEX Portal (Tissue expression)GSPT1
Human Protein AtlasENSG00000103342-GSPT1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP15170   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP15170  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP15170
PhosPhoSitePlusP15170
Domaine pattern : Prosite (Expaxy)G_TR_1 (PS00301)    G_TR_2 (PS51722)   
Domains : Interpro (EBI)EFTu-like_2    G_TR_CS    P-loop_NTPase    T_Tr_GTP-bd_dom    Transl_B-barrel_sf    Transl_elong_EF1A/Init_IF2_C    Transl_elong_EFTu/EF1A_C   
Domain families : Pfam (Sanger)GTP_EFTU (PF00009)    GTP_EFTU_D2 (PF03144)    GTP_EFTU_D3 (PF03143)   
Domain families : Pfam (NCBI)pfam00009    pfam03144    pfam03143   
Conserved Domain (NCBI)GSPT1
PDB (RSDB)3E1Y    3J5Y    3KUI    4D61    5HXB    5LZT   
PDB Europe3E1Y    3J5Y    3KUI    4D61    5HXB    5LZT   
PDB (PDBSum)3E1Y    3J5Y    3KUI    4D61    5HXB    5LZT   
PDB (IMB)3E1Y    3J5Y    3KUI    4D61    5HXB    5LZT   
Structural Biology KnowledgeBase3E1Y    3J5Y    3KUI    4D61    5HXB    5LZT   
SCOP (Structural Classification of Proteins)3E1Y    3J5Y    3KUI    4D61    5HXB    5LZT   
CATH (Classification of proteins structures)3E1Y    3J5Y    3KUI    4D61    5HXB    5LZT   
SuperfamilyP15170
AlphaFold pdb e-kbP15170   
Human Protein Atlas [tissue]ENSG00000103342-GSPT1 [tissue]
HPRD00753
Protein Interaction databases
DIP (DOE-UCLA)P15170
IntAct (EBI)P15170
BioGRIDGSPT1
STRING (EMBL)GSPT1
ZODIACGSPT1
Ontologies - Pathways
QuickGOP15170
Ontology : AmiGOG1/S transition of mitotic cell cycle  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  cytoplasmic translational termination  RNA binding  translation release factor activity  translation release factor activity  GTPase activity  GTPase activity  protein binding  GTP binding  cytosol  translation  regulation of translational termination  protein methylation  translation release factor complex  
Ontology : EGO-EBIG1/S transition of mitotic cell cycle  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  cytoplasmic translational termination  RNA binding  translation release factor activity  translation release factor activity  GTPase activity  GTPase activity  protein binding  GTP binding  cytosol  translation  regulation of translational termination  protein methylation  translation release factor complex  
Pathways : KEGGmRNA surveillance pathway   
NDEx NetworkGSPT1
Atlas of Cancer Signalling NetworkGSPT1
Wikipedia pathwaysGSPT1
Orthology - Evolution
OrthoDB2935
GeneTree (enSembl)ENSG00000103342
Phylogenetic Trees/Animal Genes : TreeFamGSPT1
Homologs : HomoloGeneGSPT1
Homology/Alignments : Family Browser (UCSC)GSPT1
Gene fusions - Rearrangements
Fusion : MitelmanTXNDC11/GSPT1 [16p13.13/16p13.13]  
Fusion : QuiverGSPT1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGSPT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GSPT1
dbVarGSPT1
ClinVarGSPT1
MonarchGSPT1
1000_GenomesGSPT1 
Exome Variant ServerGSPT1
GNOMAD BrowserENSG00000103342
Varsome BrowserGSPT1
ACMGGSPT1 variants
VarityP15170
Genomic Variants (DGV)GSPT1 [DGVbeta]
DECIPHERGSPT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGSPT1 
Mutations
ICGC Data PortalGSPT1 
TCGA Data PortalGSPT1 
Broad Tumor PortalGSPT1
OASIS PortalGSPT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGSPT1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGSPT1
Mutations and Diseases : HGMDGSPT1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGSPT1
DgiDB (Drug Gene Interaction Database)GSPT1
DoCM (Curated mutations)GSPT1
CIViC (Clinical Interpretations of Variants in Cancer)GSPT1
Cancer3DGSPT1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM139259   
Orphanet
DisGeNETGSPT1
MedgenGSPT1
Genetic Testing Registry GSPT1
NextProtP15170 [Medical]
GENETestsGSPT1
Target ValidationGSPT1
Huge Navigator GSPT1 [HugePedia]
ClinGenGSPT1
Clinical trials, drugs, therapy
MyCancerGenomeGSPT1
Protein Interactions : CTDGSPT1
Pharm GKB GenePA29012
PharosP15170
Clinical trialGSPT1
Miscellaneous
canSAR (ICR)GSPT1
HarmonizomeGSPT1
DataMed IndexGSPT1
Probes
Litterature
PubMed90 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGSPT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:11:37 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.