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GSTA3 (glutathione S-transferase alpha 3)

Identity

Other namesGSTA3-3
GTA3
HGNC (Hugo) GSTA3
LocusID (NCBI) 2940
Location 6p12.2
Location_base_pair Starts at 52761439 and ends at 52774496 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GSTA3   4628
Entrez_Gene (NCBI)GSTA3  2940  glutathione S-transferase alpha 3
Cards
GeneCards (Weizmann)GSTA3
Ensembl (Hinxton)ENSG00000174156 [Gene_View]  chr6:52761439-52774496 [Contig_View]  GSTA3 [Vega]
AceView (NCBI)GSTA3
Genatlas (Paris)GSTA3
SOURCE (Stanford)NM_000847
Genomic and cartography
GoldenPath (UCSC)GSTA3  -  6p12.2   chr6:52761439-52774496 -  6p12.2   [Description]    (hg19-Feb_2009)
EnsemblGSTA3 - 6p12.2 [CytoView]
Mapping of homologs : NCBIGSTA3 [Mapview]
OMIM605449   
Gene and transcription
Genbank (Entrez)AA846513 AF020919 AF508266 AI199811 BC020619
RefSeq transcript (SRS)NM_000847
RefSeq transcript (Entrez)NM_000847
RefSeq genomic (SRS)AC_000138 NC_000006 NC_018917 NT_007592 NW_001838981 NW_004078026
RefSeq genomic (Entrez)AC_000138 NC_000006 NC_018917 NT_007592 NW_001838981 NW_004078026
Consensus coding sequences : CCDS (NCBI)GSTA3
Cluster EST : UnigeneHs.102484 [ SRS ] Hs.102484 [ NCBI ]
CGAP (NCI)Hs.102484
Alternative Splicing : Fast-db (Paris)GSHG0026682
Alternative Splicing GalleryENSG00000174156
Gene ExpressionGSTA3 [ NCBI-GEO ]   GSTA3 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16772 (SRS) Q16772 (Uniprot)
NextProtQ16772
With graphics : InterProQ16772
Splice isoforms : SwissVarQ16772(Swissvar)
Domaine pattern : Prosite (SRS)GST_CTER (PS50405)    GST_NTER (PS50404)   
Domaine pattern : Prosite (Expaxy)GST_CTER (PS50405)    GST_NTER (PS50404)   
Domains : Interpro (SRS)Glutathione-S-Trfase_C-like    Glutathione_S-Trfase_N    Glutathione_S_Trfase/Cl_chnl_C    GST_alpha    GST_C    Thioredoxin-like_fold   
Domains : Interpro (EBI)Glutathione-S-Trfase_C-like    Glutathione_S-Trfase_N    Glutathione_S_Trfase/Cl_chnl_C    GST_alpha    GST_C    Thioredoxin-like_fold   
Related proteins : CluSTrQ16772
Domain families : Pfam (SRS)GST_C (PF00043)    GST_N (PF02798)   
Domain families : Pfam (Sanger)GST_C (PF00043)    GST_N (PF02798)   
Domain families : Pfam (NCBI)pfam00043    pfam02798   
DMDM2940
Blocks (Seattle)Q16772
PDB (SRS)1TDI    2VCV   
PDB (PDBSum)1TDI    2VCV   
PDB (IMB)1TDI    2VCV   
PDB (RSDB)1TDI    2VCV   
Human Protein AtlasENSG00000174156
HPRD07290
IPIIPI00003929   IPI00645674   IPI00644207   
Protein Interaction databases
DIP (DOE-UCLA)Q16772
IntAct (EBI)Q16772
FunCoupENSG00000174156
REACTOMEGSTA3
Protein Interaction Database2940
BioGRIDGSTA3
InParanoidQ16772
Interologous Interaction database Q16772
IntegromeDBGSTA3
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GSTA3
SNP (GeneSNP Utah)GSTA3
SNP : HGBaseGSTA3
Genetic variants : HAPMAPGSTA3
Somatic Mutations in Cancer : COSMICGSTA3 
CONAN: Copy Number AnalysisGSTA3 
Mutations and Diseases : HGMDGSTA3
OMIM605449   
GENETests605449   
Disease Genetic AssociationGSTA3
Huge Navigator GSTA3 [HugePedia]  GSTA3 [HugeCancerGEM]
Genomic VariantsGSTA3  GSTA3 [DGVbeta]
snp3D : Map Gene to Disease2940
General knowledge
Homologs : HomoloGeneGSTA3
Homology/Alignments : Family Browser (UCSC)GSTA3
Phylogenetic Trees/Animal Genes : TreeFamGSTA3
Catalytic activity : Enzyme2.5.1.18 [ Enzyme-Expasy ]   2.5.1.18 [ Enzyme-SRS ]   2.5.1.18 [ IntEnz-EBI ]   2.5.1.18 [ BRENDA ]   2.5.1.18 [ KEGG ]   
Chemical/Protein Interactions : CTD2940
Chemical/Pharm GKB GenePA29018
Clinical trialGSTA3
Cancer Resource (Charite)ENSG00000174156
Ontology : AmiGOglutathione transferase activity  cytosol  glutathione metabolic process  xenobiotic metabolic process  small molecule metabolic process  
Ontology : EGO-EBIglutathione transferase activity  cytosol  glutathione metabolic process  xenobiotic metabolic process  small molecule metabolic process  
Pathways : KEGGGlutathione metabolismMetabolism of xenobiotics by cytochrome P450
Other databases
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
PubGeneGSTA3
iHOPGSTA3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:41:12 CEST 2013
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