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GSTA3 (glutathione S-transferase alpha 3)

Identity

Alias_namesglutathione S-transferase A3
Other aliasGSTA3-3
GTA3
HGNC (Hugo) GSTA3
LocusID (NCBI) 2940
Atlas_Id 40766
Location 6p12.2  [Link to chromosome band 6p12]
Location_base_pair Starts at 52896641 and ends at 52909698 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GSTA3   4628
Cards
Entrez_Gene (NCBI)GSTA3  2940  glutathione S-transferase alpha 3
AliasesGSTA3-3; GTA3
GeneCards (Weizmann)GSTA3
Ensembl hg19 (Hinxton)ENSG00000174156 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174156 [Gene_View]  ENSG00000174156 [Sequence]  chr6:52896641-52909698 [Contig_View]  GSTA3 [Vega]
ICGC DataPortalENSG00000174156
TCGA cBioPortalGSTA3
AceView (NCBI)GSTA3
Genatlas (Paris)GSTA3
WikiGenes2940
SOURCE (Princeton)GSTA3
Genetics Home Reference (NIH)GSTA3
Genomic and cartography
GoldenPath hg38 (UCSC)GSTA3  -     chr6:52896641-52909698 -  6p12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GSTA3  -     6p12.2   [Description]    (hg19-Feb_2009)
EnsemblGSTA3 - 6p12.2 [CytoView hg19]  GSTA3 - 6p12.2 [CytoView hg38]
Mapping of homologs : NCBIGSTA3 [Mapview hg19]  GSTA3 [Mapview hg38]
OMIM605449   
Gene and transcription
Genbank (Entrez)AA846513 AF020919 AF508266 AI199811 BC020619
RefSeq transcript (Entrez)NM_000847 NM_001363542
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GSTA3
Cluster EST : UnigeneHs.102484 [ NCBI ]
CGAP (NCI)Hs.102484
Alternative Splicing GalleryENSG00000174156
Gene ExpressionGSTA3 [ NCBI-GEO ]   GSTA3 [ EBI - ARRAY_EXPRESS ]   GSTA3 [ SEEK ]   GSTA3 [ MEM ]
Gene Expression Viewer (FireBrowse)GSTA3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2940
GTEX Portal (Tissue expression)GSTA3
Human Protein AtlasENSG00000174156-GSTA3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16772   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16772  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16772
Splice isoforms : SwissVarQ16772
Catalytic activity : Enzyme2.5.1.18 [ Enzyme-Expasy ]   2.5.1.182.5.1.18 [ IntEnz-EBI ]   2.5.1.18 [ BRENDA ]   2.5.1.18 [ KEGG ]   
PhosPhoSitePlusQ16772
Domaine pattern : Prosite (Expaxy)GST_CTER (PS50405)    GST_NTER (PS50404)   
Domains : Interpro (EBI)Glutathione-S-Trfase_C-like    Glutathione-S-Trfase_C_sf    Glutathione_S-Trfase_N    GST_alpha    GST_C    Thioredoxin-like_sf   
Domain families : Pfam (Sanger)GST_C_3 (PF14497)    GST_N (PF02798)   
Domain families : Pfam (NCBI)pfam14497    pfam02798   
Conserved Domain (NCBI)GSTA3
DMDM Disease mutations2940
Blocks (Seattle)GSTA3
PDB (SRS)1TDI    2VCV   
PDB (PDBSum)1TDI    2VCV   
PDB (IMB)1TDI    2VCV   
PDB (RSDB)1TDI    2VCV   
Structural Biology KnowledgeBase1TDI    2VCV   
SCOP (Structural Classification of Proteins)1TDI    2VCV   
CATH (Classification of proteins structures)1TDI    2VCV   
SuperfamilyQ16772
Human Protein Atlas [tissue]ENSG00000174156-GSTA3 [tissue]
Peptide AtlasQ16772
HPRD07290
IPIIPI00003929   IPI00645674   IPI00644207   
Protein Interaction databases
DIP (DOE-UCLA)Q16772
IntAct (EBI)Q16772
FunCoupENSG00000174156
BioGRIDGSTA3
STRING (EMBL)GSTA3
ZODIACGSTA3
Ontologies - Pathways
QuickGOQ16772
Ontology : AmiGOglutathione transferase activity  glutathione transferase activity  cytosol  cytosol  glutathione metabolic process  extracellular exosome  glutathione derivative biosynthetic process  
Ontology : EGO-EBIglutathione transferase activity  glutathione transferase activity  cytosol  cytosol  glutathione metabolic process  extracellular exosome  glutathione derivative biosynthetic process  
Pathways : KEGGGlutathione metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Chemical carcinogenesis   
NDEx NetworkGSTA3
Atlas of Cancer Signalling NetworkGSTA3
Wikipedia pathwaysGSTA3
Orthology - Evolution
OrthoDB2940
GeneTree (enSembl)ENSG00000174156
Phylogenetic Trees/Animal Genes : TreeFamGSTA3
HOVERGENQ16772
HOGENOMQ16772
Homologs : HomoloGeneGSTA3
Homology/Alignments : Family Browser (UCSC)GSTA3
Gene fusions - Rearrangements
Fusion : QuiverGSTA3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGSTA3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GSTA3
dbVarGSTA3
ClinVarGSTA3
1000_GenomesGSTA3 
Exome Variant ServerGSTA3
ExAC (Exome Aggregation Consortium)ENSG00000174156
GNOMAD BrowserENSG00000174156
Varsome BrowserGSTA3
Genetic variants : HAPMAP2940
Genomic Variants (DGV)GSTA3 [DGVbeta]
DECIPHERGSTA3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGSTA3 
Mutations
ICGC Data PortalGSTA3 
TCGA Data PortalGSTA3 
Broad Tumor PortalGSTA3
OASIS PortalGSTA3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGSTA3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGSTA3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GSTA3
DgiDB (Drug Gene Interaction Database)GSTA3
DoCM (Curated mutations)GSTA3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GSTA3 (select a term)
intoGenGSTA3
Cancer3DGSTA3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605449   
Orphanet
DisGeNETGSTA3
MedgenGSTA3
Genetic Testing Registry GSTA3
NextProtQ16772 [Medical]
TSGene2940
GENETestsGSTA3
Target ValidationGSTA3
Huge Navigator GSTA3 [HugePedia]
snp3D : Map Gene to Disease2940
BioCentury BCIQGSTA3
ClinGenGSTA3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2940
Chemical/Pharm GKB GenePA29018
Clinical trialGSTA3
Miscellaneous
canSAR (ICR)GSTA3 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGSTA3
EVEXGSTA3
GoPubMedGSTA3
iHOPGSTA3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:09:46 CET 2018

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