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GSTA5 (glutathione S-transferase alpha 5)

Identity

Alias_namesglutathione S-transferase A5
Other alias-
HGNC (Hugo) GSTA5
LocusID (NCBI) 221357
Atlas_Id 64076
Location 6p12.2  [Link to chromosome band 6p12]
Location_base_pair Starts at 52831743 and ends at 52846095 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GSTA5   19662
Cards
Entrez_Gene (NCBI)GSTA5  221357  glutathione S-transferase alpha 5
Aliases
GeneCards (Weizmann)GSTA5
Ensembl hg19 (Hinxton)ENSG00000182793 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000182793 [Gene_View]  ENSG00000182793 [Sequence]  chr6:52831743-52846095 [Contig_View]  GSTA5 [Vega]
ICGC DataPortalENSG00000182793
TCGA cBioPortalGSTA5
AceView (NCBI)GSTA5
Genatlas (Paris)GSTA5
WikiGenes221357
SOURCE (Princeton)GSTA5
Genetics Home Reference (NIH)GSTA5
Genomic and cartography
GoldenPath hg38 (UCSC)GSTA5  -     chr6:52831743-52846095 -  6p12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GSTA5  -     6p12.2   [Description]    (hg19-Feb_2009)
EnsemblGSTA5 - 6p12.2 [CytoView hg19]  GSTA5 - 6p12.2 [CytoView hg38]
Mapping of homologs : NCBIGSTA5 [Mapview hg19]  GSTA5 [Mapview hg38]
OMIM607605   
Gene and transcription
Genbank (Entrez)BC146332 BC148816
RefSeq transcript (Entrez)NM_153699
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GSTA5
Cluster EST : UnigeneHs.646984 [ NCBI ]
CGAP (NCI)Hs.646984
Alternative Splicing GalleryENSG00000182793
Gene ExpressionGSTA5 [ NCBI-GEO ]   GSTA5 [ EBI - ARRAY_EXPRESS ]   GSTA5 [ SEEK ]   GSTA5 [ MEM ]
Gene Expression Viewer (FireBrowse)GSTA5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)221357
GTEX Portal (Tissue expression)GSTA5
Human Protein AtlasENSG00000182793-GSTA5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7RTV2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7RTV2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7RTV2
Splice isoforms : SwissVarQ7RTV2
Catalytic activity : Enzyme2.5.1.18 [ Enzyme-Expasy ]   2.5.1.182.5.1.18 [ IntEnz-EBI ]   2.5.1.18 [ BRENDA ]   2.5.1.18 [ KEGG ]   
PhosPhoSitePlusQ7RTV2
Domaine pattern : Prosite (Expaxy)GST_CTER (PS50405)    GST_NTER (PS50404)   
Domains : Interpro (EBI)Glutathione-S-Trfase_C-like    Glutathione_S-Trfase_N    GST_alpha    GST_C    Thioredoxin-like_fold   
Domain families : Pfam (Sanger)GST_C_3 (PF14497)    GST_N (PF02798)   
Domain families : Pfam (NCBI)pfam14497    pfam02798   
Conserved Domain (NCBI)GSTA5
DMDM Disease mutations221357
Blocks (Seattle)GSTA5
SuperfamilyQ7RTV2
Human Protein Atlas [tissue]ENSG00000182793-GSTA5 [tissue]
Peptide AtlasQ7RTV2
HPRD09620
IPIIPI00170604   
Protein Interaction databases
DIP (DOE-UCLA)Q7RTV2
IntAct (EBI)Q7RTV2
FunCoupENSG00000182793
BioGRIDGSTA5
STRING (EMBL)GSTA5
ZODIACGSTA5
Ontologies - Pathways
QuickGOQ7RTV2
Ontology : AmiGOglutathione transferase activity  cytosol  glutathione metabolic process  extracellular exosome  
Ontology : EGO-EBIglutathione transferase activity  cytosol  glutathione metabolic process  extracellular exosome  
Pathways : KEGGGlutathione metabolism    Metabolism of xenobiotics by cytochrome P450   
NDEx NetworkGSTA5
Atlas of Cancer Signalling NetworkGSTA5
Wikipedia pathwaysGSTA5
Orthology - Evolution
OrthoDB221357
GeneTree (enSembl)ENSG00000182793
Phylogenetic Trees/Animal Genes : TreeFamGSTA5
HOVERGENQ7RTV2
HOGENOMQ7RTV2
Homologs : HomoloGeneGSTA5
Homology/Alignments : Family Browser (UCSC)GSTA5
Gene fusions - Rearrangements
Fusion : QuiverGSTA5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGSTA5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GSTA5
dbVarGSTA5
ClinVarGSTA5
1000_GenomesGSTA5 
Exome Variant ServerGSTA5
ExAC (Exome Aggregation Consortium)ENSG00000182793
GNOMAD BrowserENSG00000182793
Varsome BrowserGSTA5
Genetic variants : HAPMAP221357
Genomic Variants (DGV)GSTA5 [DGVbeta]
DECIPHERGSTA5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGSTA5 
Mutations
ICGC Data PortalGSTA5 
TCGA Data PortalGSTA5 
Broad Tumor PortalGSTA5
OASIS PortalGSTA5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGSTA5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGSTA5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GSTA5
DgiDB (Drug Gene Interaction Database)GSTA5
DoCM (Curated mutations)GSTA5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GSTA5 (select a term)
intoGenGSTA5
Cancer3DGSTA5(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607605   
Orphanet
DisGeNETGSTA5
MedgenGSTA5
Genetic Testing Registry GSTA5
NextProtQ7RTV2 [Medical]
TSGene221357
GENETestsGSTA5
Target ValidationGSTA5
Huge Navigator GSTA5 [HugePedia]
snp3D : Map Gene to Disease221357
BioCentury BCIQGSTA5
ClinGenGSTA5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD221357
Chemical/Pharm GKB GenePA134962856
Clinical trialGSTA5
Miscellaneous
canSAR (ICR)GSTA5 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGSTA5
EVEXGSTA5
GoPubMedGSTA5
iHOPGSTA5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 13:48:11 CEST 2018

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