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GSTK1 (glutathione S-transferase kappa 1)

Identity

Alias_symbol (synonym)GST13
Other aliasGST
GST 13-13
GST13-13
GSTK1-1
hGSTK1
HGNC (Hugo) GSTK1
LocusID (NCBI) 373156
Atlas_Id 53300
Location 7q34  [Link to chromosome band 7q34]
Location_base_pair Starts at 143263429 and ends at 143269129 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GSTK1   16906
Cards
Entrez_Gene (NCBI)GSTK1  373156  glutathione S-transferase kappa 1
AliasesGST; GST; GST13; GST13-13; 
GSTK1-1; hGSTK1
GeneCards (Weizmann)GSTK1
Ensembl hg19 (Hinxton)ENSG00000197448 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197448 [Gene_View]  ENSG00000197448 [Sequence]  chr7:143263429-143269129 [Contig_View]  GSTK1 [Vega]
ICGC DataPortalENSG00000197448
TCGA cBioPortalGSTK1
AceView (NCBI)GSTK1
Genatlas (Paris)GSTK1
WikiGenes373156
SOURCE (Princeton)GSTK1
Genetics Home Reference (NIH)GSTK1
Genomic and cartography
GoldenPath hg38 (UCSC)GSTK1  -     chr7:143263429-143269129 +  7q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GSTK1  -     7q34   [Description]    (hg19-Feb_2009)
EnsemblGSTK1 - 7q34 [CytoView hg19]  GSTK1 - 7q34 [CytoView hg38]
Mapping of homologs : NCBIGSTK1 [Mapview hg19]  GSTK1 [Mapview hg38]
OMIM602321   
Gene and transcription
Genbank (Entrez)AF068287 AF070657 AF087849 AK000640 AK095263
RefSeq transcript (Entrez)NM_001143679 NM_001143680 NM_001143681 NM_015917
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GSTK1
Cluster EST : UnigeneHs.390667 [ NCBI ]
CGAP (NCI)Hs.390667
Alternative Splicing GalleryENSG00000197448
Gene ExpressionGSTK1 [ NCBI-GEO ]   GSTK1 [ EBI - ARRAY_EXPRESS ]   GSTK1 [ SEEK ]   GSTK1 [ MEM ]
Gene Expression Viewer (FireBrowse)GSTK1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)373156
GTEX Portal (Tissue expression)GSTK1
Human Protein AtlasENSG00000197448-GSTK1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2Q3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2Q3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2Q3
Splice isoforms : SwissVarQ9Y2Q3
Catalytic activity : Enzyme2.5.1.18 [ Enzyme-Expasy ]   2.5.1.182.5.1.18 [ IntEnz-EBI ]   2.5.1.18 [ BRENDA ]   2.5.1.18 [ KEGG ]   
PhosPhoSitePlusQ9Y2Q3
Domains : Interpro (EBI)DSBA-like_thioredoxin_dom    HCCAis_GSTk    Thioredoxin-like_sf   
Domain families : Pfam (Sanger)DSBA (PF01323)   
Domain families : Pfam (NCBI)pfam01323   
Conserved Domain (NCBI)GSTK1
DMDM Disease mutations373156
Blocks (Seattle)GSTK1
PDB (SRS)1YZX    3RPN    3RPP   
PDB (PDBSum)1YZX    3RPN    3RPP   
PDB (IMB)1YZX    3RPN    3RPP   
PDB (RSDB)1YZX    3RPN    3RPP   
Structural Biology KnowledgeBase1YZX    3RPN    3RPP   
SCOP (Structural Classification of Proteins)1YZX    3RPN    3RPP   
CATH (Classification of proteins structures)1YZX    3RPN    3RPP   
SuperfamilyQ9Y2Q3
Human Protein Atlas [tissue]ENSG00000197448-GSTK1 [tissue]
Peptide AtlasQ9Y2Q3
IPIIPI00219673   IPI00440703   IPI00917714   IPI00909432   IPI00917331   IPI00917580   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2Q3
IntAct (EBI)Q9Y2Q3
FunCoupENSG00000197448
BioGRIDGSTK1
STRING (EMBL)GSTK1
ZODIACGSTK1
Ontologies - Pathways
QuickGOQ9Y2Q3
Ontology : AmiGOglutathione transferase activity  glutathione transferase activity  glutathione transferase activity  glutathione peroxidase activity  glutathione peroxidase activity  signaling receptor binding  protein binding  intracellular  mitochondrion  mitochondrial matrix  peroxisome  peroxisome  peroxisomal matrix  cytosol  protein targeting to peroxisome  glutathione metabolic process  protein disulfide oxidoreductase activity  membrane  epithelial cell differentiation  oxidation-reduction process  extracellular exosome  cellular oxidant detoxification  glutathione derivative biosynthetic process  
Ontology : EGO-EBIglutathione transferase activity  glutathione transferase activity  glutathione transferase activity  glutathione peroxidase activity  glutathione peroxidase activity  signaling receptor binding  protein binding  intracellular  mitochondrion  mitochondrial matrix  peroxisome  peroxisome  peroxisomal matrix  cytosol  protein targeting to peroxisome  glutathione metabolic process  protein disulfide oxidoreductase activity  membrane  epithelial cell differentiation  oxidation-reduction process  extracellular exosome  cellular oxidant detoxification  glutathione derivative biosynthetic process  
Pathways : KEGGGlutathione metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Peroxisome    Chemical carcinogenesis   
NDEx NetworkGSTK1
Atlas of Cancer Signalling NetworkGSTK1
Wikipedia pathwaysGSTK1
Orthology - Evolution
OrthoDB373156
GeneTree (enSembl)ENSG00000197448
Phylogenetic Trees/Animal Genes : TreeFamGSTK1
HOVERGENQ9Y2Q3
HOGENOMQ9Y2Q3
Homologs : HomoloGeneGSTK1
Homology/Alignments : Family Browser (UCSC)GSTK1
Gene fusions - Rearrangements
Fusion : QuiverGSTK1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGSTK1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GSTK1
dbVarGSTK1
ClinVarGSTK1
1000_GenomesGSTK1 
Exome Variant ServerGSTK1
ExAC (Exome Aggregation Consortium)ENSG00000197448
GNOMAD BrowserENSG00000197448
Varsome BrowserGSTK1
Genetic variants : HAPMAP373156
Genomic Variants (DGV)GSTK1 [DGVbeta]
DECIPHERGSTK1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGSTK1 
Mutations
ICGC Data PortalGSTK1 
TCGA Data PortalGSTK1 
Broad Tumor PortalGSTK1
OASIS PortalGSTK1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGSTK1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGSTK1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch GSTK1
DgiDB (Drug Gene Interaction Database)GSTK1
DoCM (Curated mutations)GSTK1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GSTK1 (select a term)
intoGenGSTK1
Cancer3DGSTK1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602321   
Orphanet
DisGeNETGSTK1
MedgenGSTK1
Genetic Testing Registry GSTK1
NextProtQ9Y2Q3 [Medical]
TSGene373156
GENETestsGSTK1
Target ValidationGSTK1
Huge Navigator GSTK1 [HugePedia]
snp3D : Map Gene to Disease373156
BioCentury BCIQGSTK1
ClinGenGSTK1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD373156
Chemical/Pharm GKB GenePA134948237
Clinical trialGSTK1
Miscellaneous
canSAR (ICR)GSTK1 (select the gene name)
Probes
Litterature
PubMed54 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGSTK1
EVEXGSTK1
GoPubMedGSTK1
iHOPGSTK1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:09:47 CET 2018

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