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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret jlhuret@AtlasGeneticsOncology.org
Donations are also welcome
If each casual visitor gives 3 Euros or Dollars, the Atlas is saved in a week !
If each professional gives 100 Euros or Dollars once a year (now), the Atlas is saved in 2 weeks !
Don't let the Atlas imminent demise
Note: we send fiscal receipts for donations equal or above 50 Euros or Dollars

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GSTM1 (glutathione S-transferase mu 1)

Identity

Other namesGST1
GSTM1-1
GSTM1a-1a
GSTM1b-1b
GTH4
GTM1
H-B
MU
MU-1
HGNC (Hugo) GSTM1
LocusID (NCBI) 2944
Location 1p13.3
Location_base_pair Starts at 110230418 and ends at 110236367 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GSTM1   4632
Cards
Entrez_Gene (NCBI)GSTM1  2944  glutathione S-transferase mu 1
GeneCards (Weizmann)GSTM1
Ensembl hg19 (Hinxton)ENSG00000134184 [Gene_View]  chr1:110230418-110236367 [Contig_View]  GSTM1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000134184 [Gene_View]  chr1:110230418-110236367 [Contig_View]  GSTM1 [Vega]
ICGC DataPortalENSG00000134184
cBioPortalGSTM1
AceView (NCBI)GSTM1
Genatlas (Paris)GSTM1
WikiGenes2944
SOURCE (Princeton)GSTM1
Genomic and cartography
GoldenPath hg19 (UCSC)GSTM1  -     chr1:110230418-110236367 +  1p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GSTM1  -     1p13.3   [Description]    (hg38-Dec_2013)
EnsemblGSTM1 - 1p13.3 [CytoView hg19]  GSTM1 - 1p13.3 [CytoView hg38]
Mapping of homologs : NCBIGSTM1 [Mapview hg19]  GSTM1 [Mapview hg38]
OMIM138350   
Gene and transcription
Genbank (Entrez)AY510272 AY532926 AY532927 BC024005 BC036805
RefSeq transcript (Entrez)NM_000561 NM_146421
RefSeq genomic (Entrez)NC_000001 NG_009246 NT_032977
Consensus coding sequences : CCDS (NCBI)GSTM1
Cluster EST : UnigeneHs.301961 [ NCBI ]
CGAP (NCI)Hs.301961
Alternative Splicing : Fast-db (Paris)GSHG0000779
Alternative Splicing GalleryENSG00000134184
Gene ExpressionGSTM1 [ NCBI-GEO ]     GSTM1 [ SEEK ]   GSTM1 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09488 (Uniprot)
NextProtP09488  [Medical]
With graphics : InterProP09488
Splice isoforms : SwissVarP09488 (Swissvar)
Catalytic activity : Enzyme2.5.1.18 [ Enzyme-Expasy ]   2.5.1.182.5.1.18 [ IntEnz-EBI ]   2.5.1.18 [ BRENDA ]   2.5.1.18 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)GST_CTER (PS50405)    GST_NTER (PS50404)   
Domains : Interpro (EBI)Glutathione-S-Trfase_C-like    Glutathione_S-Trfase_N    GST_C    GST_mu    Thioredoxin-like_fold   
Related proteins : CluSTrP09488
Domain families : Pfam (Sanger)GST_C (PF00043)    GST_N (PF02798)   
Domain families : Pfam (NCBI)pfam00043    pfam02798   
DMDM Disease mutations2944
Blocks (Seattle)P09488
PDB (SRS)1GTU    1XW6    1XWK    1YJ6    2F3M   
PDB (PDBSum)1GTU    1XW6    1XWK    1YJ6    2F3M   
PDB (IMB)1GTU    1XW6    1XWK    1YJ6    2F3M   
PDB (RSDB)1GTU    1XW6    1XWK    1YJ6    2F3M   
Human Protein AtlasENSG00000134184
Peptide AtlasP09488
HPRD00707
IPIIPI00218831   IPI00152326   IPI00647885   IPI00640363   
Protein Interaction databases
DIP (DOE-UCLA)P09488
IntAct (EBI)P09488
FunCoupENSG00000134184
BioGRIDGSTM1
IntegromeDBGSTM1
STRING (EMBL)GSTM1
Ontologies - Pathways
QuickGOP09488
Ontology : AmiGOglutathione transferase activity  cytoplasm  cytosol  glutathione metabolic process  xenobiotic metabolic process  nitrobenzene metabolic process  enzyme binding  xenobiotic catabolic process  protein homodimerization activity  glutathione binding  small molecule metabolic process  cellular detoxification of nitrogen compound  glutathione derivative biosynthetic process  
Ontology : EGO-EBIglutathione transferase activity  cytoplasm  cytosol  glutathione metabolic process  xenobiotic metabolic process  nitrobenzene metabolic process  enzyme binding  xenobiotic catabolic process  protein homodimerization activity  glutathione binding  small molecule metabolic process  cellular detoxification of nitrogen compound  glutathione derivative biosynthetic process  
Pathways : KEGGGlutathione metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Chemical carcinogenesis   
Protein Interaction DatabaseGSTM1
DoCM (Curated mutations)GSTM1
Wikipedia pathwaysGSTM1
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerGSTM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GSTM1
dbVarGSTM1
ClinVarGSTM1
1000_GenomesGSTM1 
Exome Variant ServerGSTM1
SNP (GeneSNP Utah)GSTM1
SNP : HGBaseGSTM1
Genetic variants : HAPMAPGSTM1
Genomic Variants (DGV)GSTM1 [DGVbeta]
Mutations
ICGC Data PortalENSG00000134184 
Somatic Mutations in Cancer : COSMICGSTM1 
CONAN: Copy Number AnalysisGSTM1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Pharmacogenomics of Infectious Diseases (PGx_IfD )
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:110230418-110236367
Mutations and Diseases : HGMDGSTM1
OMIM138350   
MedgenGSTM1
NextProtP09488 [Medical]
GENETestsGSTM1
Disease Genetic AssociationGSTM1
Huge Navigator GSTM1 [HugePedia]  GSTM1 [HugeCancerGEM]
snp3D : Map Gene to Disease2944
DGIdb (Drug Gene Interaction db)GSTM1
General knowledge
Homologs : HomoloGeneGSTM1
Homology/Alignments : Family Browser (UCSC)GSTM1
Phylogenetic Trees/Animal Genes : TreeFamGSTM1
Chemical/Protein Interactions : CTD2944
Chemical/Pharm GKB GenePA182
Clinical trialGSTM1
Cancer Resource (Charite)ENSG00000134184
Other databases
Probes
Litterature
PubMed499 Pubmed reference(s) in Entrez
CoreMineGSTM1
GoPubMedGSTM1
iHOPGSTM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Mar 28 15:33:14 CET 2015

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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.