Atlas of Genetics and Cytogenetics in Oncology and Haematology

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GSTM1 (glutathione S-transferase mu 1)

Identity

Other namesGST1
GSTM1-1
GSTM1a-1a
GSTM1b-1b
GTH4
GTM1
H-B
MU
MU-1
HGNC (Hugo) GSTM1
LocusID (NCBI) 2944
Location 1p13.3
Location_base_pair Starts at 110230418 and ends at 110236367 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GSTM1   4632
Cards
Entrez_Gene (NCBI)GSTM1  2944  glutathione S-transferase mu 1
GeneCards (Weizmann)GSTM1
Ensembl (Hinxton)ENSG00000134184 [Gene_View]  chr1:110230418-110236367 [Contig_View]  GSTM1 [Vega]
ICGC DataPortalENSG00000134184
cBioPortalGSTM1
AceView (NCBI)GSTM1
Genatlas (Paris)GSTM1
WikiGenes2944
SOURCE (Princeton)NM_000561 NM_146421
Genomic and cartography
GoldenPath (UCSC)GSTM1  -  1p13.3   chr1:110230418-110236367 +  1p13.3   [Description]    (hg19-Feb_2009)
EnsemblGSTM1 - 1p13.3 [CytoView]
Mapping of homologs : NCBIGSTM1 [Mapview]
OMIM138350   
Gene and transcription
Genbank (Entrez)AY510272 AY532926 AY532927 BC024005 BC036805
RefSeq transcript (Entrez)NM_000561 NM_146421
RefSeq genomic (Entrez)NC_000001 NG_009246 NT_032977 NW_001841066
Consensus coding sequences : CCDS (NCBI)GSTM1
Cluster EST : UnigeneHs.301961 [ NCBI ]
CGAP (NCI)Hs.301961
Alternative Splicing : Fast-db (Paris)GSHG0000779
Alternative Splicing GalleryENSG00000134184
Gene ExpressionGSTM1 [ NCBI-GEO ]     GSTM1 [ SEEK ]   GSTM1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09488 (Uniprot)
NextProtP09488  [Medical]
With graphics : InterProP09488
Splice isoforms : SwissVarP09488 (Swissvar)
Catalytic activity : Enzyme2.5.1.18 [ Enzyme-Expasy ]   2.5.1.182.5.1.18 [ IntEnz-EBI ]   2.5.1.18 [ BRENDA ]   2.5.1.18 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)GST_CTER (PS50405)    GST_NTER (PS50404)   
Domains : Interpro (EBI)Glutathione-S-Trfase_C-like [organisation]   Glutathione_S-Trfase_N [organisation]   GST_C [organisation]   GST_mu [organisation]   Thioredoxin-like_fold [organisation]  
Related proteins : CluSTrP09488
Domain families : Pfam (Sanger)GST_C (PF00043)    GST_N (PF02798)   
Domain families : Pfam (NCBI)pfam00043    pfam02798   
DMDM Disease mutations2944
Blocks (Seattle)P09488
PDB (SRS)1GTU    1XW6    1XWK    1YJ6    2F3M   
PDB (PDBSum)1GTU    1XW6    1XWK    1YJ6    2F3M   
PDB (IMB)1GTU    1XW6    1XWK    1YJ6    2F3M   
PDB (RSDB)1GTU    1XW6    1XWK    1YJ6    2F3M   
Human Protein AtlasENSG00000134184 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP09488
HPRD00707
IPIIPI00218831   IPI00152326   IPI00647885   IPI00640363   
Protein Interaction databases
DIP (DOE-UCLA)P09488
IntAct (EBI)P09488
FunCoupENSG00000134184
BioGRIDGSTM1
InParanoidP09488
Interologous Interaction database P09488
IntegromeDBGSTM1
STRING (EMBL)GSTM1
Ontologies - Pathways
Ontology : AmiGOglutathione transferase activity  cytoplasm  cytosol  glutathione metabolic process  xenobiotic metabolic process  nitrobenzene metabolic process  enzyme binding  xenobiotic catabolic process  protein homodimerization activity  glutathione binding  small molecule metabolic process  cellular detoxification of nitrogen compound  glutathione derivative biosynthetic process  
Ontology : EGO-EBIglutathione transferase activity  cytoplasm  cytosol  glutathione metabolic process  xenobiotic metabolic process  nitrobenzene metabolic process  enzyme binding  xenobiotic catabolic process  protein homodimerization activity  glutathione binding  small molecule metabolic process  cellular detoxification of nitrogen compound  glutathione derivative biosynthetic process  
Pathways : KEGGGlutathione metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Chemical carcinogenesis   
Protein Interaction DatabaseGSTM1
Wikipedia pathwaysGSTM1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GSTM1
snp3D : Map Gene to Disease2944
SNP (GeneSNP Utah)GSTM1
SNP : HGBaseGSTM1
Genetic variants : HAPMAPGSTM1
Exome VariantGSTM1
1000_GenomesGSTM1 
ICGC programENSG00000134184 
Somatic Mutations in Cancer : COSMICGSTM1 
CONAN: Copy Number AnalysisGSTM1 
Mutations and Diseases : HGMDGSTM1
Genomic VariantsGSTM1  GSTM1 [DGVbeta]
dbVarGSTM1
ClinVarGSTM1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM138350   
MedgenGSTM1
GENETestsGSTM1
Disease Genetic AssociationGSTM1
Huge Navigator GSTM1 [HugePedia]  GSTM1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneGSTM1
Homology/Alignments : Family Browser (UCSC)GSTM1
Phylogenetic Trees/Animal Genes : TreeFamGSTM1
Chemical/Protein Interactions : CTD2944
Chemical/Pharm GKB GenePA182
Clinical trialGSTM1
Cancer Resource (Charite)ENSG00000134184
Other databases
Probes
Litterature
PubMed499 Pubmed reference(s) in Entrez
CoreMineGSTM1
iHOPGSTM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jul 11 16:57:59 CEST 2014
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