Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GSTO1 (glutathione S-transferase omega 1)

Identity

Alias_symbol (synonym)GSTTLp28
P28
Other aliasGSTO 1-1
HEL-S-21
SPG-R
HGNC (Hugo) GSTO1
LocusID (NCBI) 9446
Atlas_Id 50314
Location 10q25.1  [Link to chromosome band 10q25]
Location_base_pair Starts at 104254710 and ends at 104267464 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CPD (17q11.2) / GSTO1 (10q25.1)GSTO1 (10q25.1) / PLIN2 (9p22.1)HS3ST3A1 (17p12) / GSTO1 (10q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GSTO1   13312
Cards
Entrez_Gene (NCBI)GSTO1  9446  glutathione S-transferase omega 1
AliasesGSTO; GSTTLp28; HEL-S-21; P28; 
SPG-R
GeneCards (Weizmann)GSTO1
Ensembl hg19 (Hinxton)ENSG00000148834 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148834 [Gene_View]  chr10:104254710-104267464 [Contig_View]  GSTO1 [Vega]
ICGC DataPortalENSG00000148834
TCGA cBioPortalGSTO1
AceView (NCBI)GSTO1
Genatlas (Paris)GSTO1
WikiGenes9446
SOURCE (Princeton)GSTO1
Genetics Home Reference (NIH)GSTO1
Genomic and cartography
GoldenPath hg38 (UCSC)GSTO1  -     chr10:104254710-104267464 +  10q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GSTO1  -     10q25.1   [Description]    (hg19-Feb_2009)
EnsemblGSTO1 - 10q25.1 [CytoView hg19]  GSTO1 - 10q25.1 [CytoView hg38]
Mapping of homologs : NCBIGSTO1 [Mapview hg19]  GSTO1 [Mapview hg38]
OMIM605482   
Gene and transcription
Genbank (Entrez)AF212303 AK313680 BC000127 BX537431 CA431506
RefSeq transcript (Entrez)NM_001191002 NM_001191003 NM_004832
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GSTO1
Cluster EST : UnigeneHs.190028 [ NCBI ]
CGAP (NCI)Hs.190028
Alternative Splicing GalleryENSG00000148834
Gene ExpressionGSTO1 [ NCBI-GEO ]   GSTO1 [ EBI - ARRAY_EXPRESS ]   GSTO1 [ SEEK ]   GSTO1 [ MEM ]
Gene Expression Viewer (FireBrowse)GSTO1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9446
GTEX Portal (Tissue expression)GSTO1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP78417   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP78417  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP78417
Splice isoforms : SwissVarP78417
PhosPhoSitePlusP78417
Domaine pattern : Prosite (Expaxy)GST_CTER (PS50405)    GST_NTER (PS50404)   
Domains : Interpro (EBI)Glutathione-S-Trfase_C-like    Glutathione_S-Trfase_N    GST_C    GST_omega    Thioredoxin-like_fold   
Domain families : Pfam (Sanger)GST_C_3 (PF14497)    GST_N_3 (PF13417)   
Domain families : Pfam (NCBI)pfam14497    pfam13417   
Conserved Domain (NCBI)GSTO1
DMDM Disease mutations9446
Blocks (Seattle)GSTO1
PDB (SRS)1EEM    3LFL    3VLN    4IS0    4YQM    4YQU    4YQV   
PDB (PDBSum)1EEM    3LFL    3VLN    4IS0    4YQM    4YQU    4YQV   
PDB (IMB)1EEM    3LFL    3VLN    4IS0    4YQM    4YQU    4YQV   
PDB (RSDB)1EEM    3LFL    3VLN    4IS0    4YQM    4YQU    4YQV   
Structural Biology KnowledgeBase1EEM    3LFL    3VLN    4IS0    4YQM    4YQU    4YQV   
SCOP (Structural Classification of Proteins)1EEM    3LFL    3VLN    4IS0    4YQM    4YQU    4YQV   
CATH (Classification of proteins structures)1EEM    3LFL    3VLN    4IS0    4YQM    4YQU    4YQV   
SuperfamilyP78417
Human Protein AtlasENSG00000148834
Peptide AtlasP78417
HPRD10401
IPIIPI00019755   IPI00513927   IPI00642936   
Protein Interaction databases
DIP (DOE-UCLA)P78417
IntAct (EBI)P78417
FunCoupENSG00000148834
BioGRIDGSTO1
STRING (EMBL)GSTO1
ZODIACGSTO1
Ontologies - Pathways
QuickGOP78417
Ontology : AmiGOglutathione transferase activity  glutathione transferase activity  protein binding  cytoplasm  cytosol  regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum  regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion  positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion  oxidoreductase activity  L-ascorbic acid metabolic process  methylation  xenobiotic catabolic process  glutathione dehydrogenase (ascorbate) activity  methylarsonate reductase activity  oxidation-reduction process  negative regulation of ryanodine-sensitive calcium-release channel activity  positive regulation of ryanodine-sensitive calcium-release channel activity  extracellular exosome  cellular response to arsenic-containing substance  cellular oxidant detoxification  glutathione derivative biosynthetic process  
Ontology : EGO-EBIglutathione transferase activity  glutathione transferase activity  protein binding  cytoplasm  cytosol  regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum  regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion  positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion  oxidoreductase activity  L-ascorbic acid metabolic process  methylation  xenobiotic catabolic process  glutathione dehydrogenase (ascorbate) activity  methylarsonate reductase activity  oxidation-reduction process  negative regulation of ryanodine-sensitive calcium-release channel activity  positive regulation of ryanodine-sensitive calcium-release channel activity  extracellular exosome  cellular response to arsenic-containing substance  cellular oxidant detoxification  glutathione derivative biosynthetic process  
Pathways : KEGGGlutathione metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Chemical carcinogenesis   
NDEx NetworkGSTO1
Atlas of Cancer Signalling NetworkGSTO1
Wikipedia pathwaysGSTO1
Orthology - Evolution
OrthoDB9446
GeneTree (enSembl)ENSG00000148834
Phylogenetic Trees/Animal Genes : TreeFamGSTO1
HOVERGENP78417
HOGENOMP78417
Homologs : HomoloGeneGSTO1
Homology/Alignments : Family Browser (UCSC)GSTO1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGSTO1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GSTO1
dbVarGSTO1
ClinVarGSTO1
1000_GenomesGSTO1 
Exome Variant ServerGSTO1
ExAC (Exome Aggregation Consortium)GSTO1 (select the gene name)
Genetic variants : HAPMAP9446
Genomic Variants (DGV)GSTO1 [DGVbeta]
DECIPHERGSTO1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGSTO1 
Mutations
ICGC Data PortalGSTO1 
TCGA Data PortalGSTO1 
Broad Tumor PortalGSTO1
OASIS PortalGSTO1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGSTO1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGSTO1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GSTO1
DgiDB (Drug Gene Interaction Database)GSTO1
DoCM (Curated mutations)GSTO1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GSTO1 (select a term)
intoGenGSTO1
Cancer3DGSTO1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605482   
Orphanet
MedgenGSTO1
Genetic Testing Registry GSTO1
NextProtP78417 [Medical]
TSGene9446
GENETestsGSTO1
Target ValidationGSTO1
Huge Navigator GSTO1 [HugePedia]
snp3D : Map Gene to Disease9446
BioCentury BCIQGSTO1
ClinGenGSTO1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9446
Chemical/Pharm GKB GenePA133787054
Clinical trialGSTO1
Miscellaneous
canSAR (ICR)GSTO1 (select the gene name)
Probes
Litterature
PubMed109 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGSTO1
EVEXGSTO1
GoPubMedGSTO1
iHOPGSTO1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:54:52 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.