Atlas of Genetics and Cytogenetics in Oncology and Haematology

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GSTO2 (glutathione S-transferase omega 2)

Identity

Other aliasGSTO 2-2
bA127L20.1
HGNC (Hugo) GSTO2
LocusID (NCBI) 119391
Atlas_Id 45899
Location 10q25.1  [Link to chromosome band 10q25]
Location_base_pair Starts at 104268873 and ends at 104299418 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GSTO2 (10q25.1) / GSTO2 (10q25.1)ZFAT (8q24.22) / GSTO2 (10q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GSTO2   23064
Cards
Entrez_Gene (NCBI)GSTO2  119391  glutathione S-transferase omega 2
AliasesGSTO; bA127L20.1
GeneCards (Weizmann)GSTO2
Ensembl hg19 (Hinxton)ENSG00000065621 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000065621 [Gene_View]  ENSG00000065621 [Sequence]  chr10:104268873-104299418 [Contig_View]  GSTO2 [Vega]
ICGC DataPortalENSG00000065621
TCGA cBioPortalGSTO2
AceView (NCBI)GSTO2
Genatlas (Paris)GSTO2
WikiGenes119391
SOURCE (Princeton)GSTO2
Genetics Home Reference (NIH)GSTO2
Genomic and cartography
GoldenPath hg38 (UCSC)GSTO2  -     chr10:104268873-104299418 +  10q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GSTO2  -     10q25.1   [Description]    (hg19-Feb_2009)
GoldenPathGSTO2 - 10q25.1 [CytoView hg19]  GSTO2 - 10q25.1 [CytoView hg38]
ImmunoBaseENSG00000065621
Mapping of homologs : NCBIGSTO2 [Mapview hg19]  GSTO2 [Mapview hg38]
OMIM612314   
Gene and transcription
Genbank (Entrez)AK094412 AK094859 AK097894 AK126230 AK291886
RefSeq transcript (Entrez)NM_001191013 NM_001191014 NM_001191015 NM_183239
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GSTO2
Cluster EST : UnigeneHs.203634 [ NCBI ]
CGAP (NCI)Hs.203634
Alternative Splicing GalleryENSG00000065621
Gene ExpressionGSTO2 [ NCBI-GEO ]   GSTO2 [ EBI - ARRAY_EXPRESS ]   GSTO2 [ SEEK ]   GSTO2 [ MEM ]
Gene Expression Viewer (FireBrowse)GSTO2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)119391
GTEX Portal (Tissue expression)GSTO2
Human Protein AtlasENSG00000065621-GSTO2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H4Y5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H4Y5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H4Y5
Splice isoforms : SwissVarQ9H4Y5
Catalytic activity : Enzyme2.5.1.18|1.8.5.1|1.20.4.2 [ Enzyme-Expasy ]   2.5.1.18|1.8.5.1|1.20.4.22.5.1.18|1.8.5.1|1.20.4.2 [ IntEnz-EBI ]   2.5.1.18|1.8.5.1|1.20.4.2 [ BRENDA ]   2.5.1.18|1.8.5.1|1.20.4.2 [ KEGG ]   
PhosPhoSitePlusQ9H4Y5
Domaine pattern : Prosite (Expaxy)GST_CTER (PS50405)    GST_NTER (PS50404)   
Domains : Interpro (EBI)Glutathione-S-Trfase_C-like    Glutathione-S-Trfase_C_sf    Glutathione_S-Trfase_N    GST_omega    Thioredoxin-like_sf   
Domain families : Pfam (Sanger)GST_N_3 (PF13417)   
Domain families : Pfam (NCBI)pfam13417   
Conserved Domain (NCBI)GSTO2
DMDM Disease mutations119391
Blocks (Seattle)GSTO2
PDB (RSDB)3Q18    3Q19    3QAG   
PDB Europe3Q18    3Q19    3QAG   
PDB (PDBSum)3Q18    3Q19    3QAG   
PDB (IMB)3Q18    3Q19    3QAG   
Structural Biology KnowledgeBase3Q18    3Q19    3QAG   
SCOP (Structural Classification of Proteins)3Q18    3Q19    3QAG   
CATH (Classification of proteins structures)3Q18    3Q19    3QAG   
SuperfamilyQ9H4Y5
Human Protein Atlas [tissue]ENSG00000065621-GSTO2 [tissue]
Peptide AtlasQ9H4Y5
HPRD13614
IPIIPI00007512   IPI00909982   IPI00910837   IPI00908358   IPI00976478   IPI00647624   
Protein Interaction databases
DIP (DOE-UCLA)Q9H4Y5
IntAct (EBI)Q9H4Y5
FunCoupENSG00000065621
BioGRIDGSTO2
STRING (EMBL)GSTO2
ZODIACGSTO2
Ontologies - Pathways
QuickGOQ9H4Y5
Ontology : AmiGOglutathione transferase activity  protein binding  cytosol  xenobiotic metabolic process  oxidoreductase activity  L-ascorbic acid metabolic process  L-ascorbic acid metabolic process  identical protein binding  glutathione dehydrogenase (ascorbate) activity  glutathione dehydrogenase (ascorbate) activity  methylarsonate reductase activity  oxidation-reduction process  oxidation-reduction process  extracellular exosome  cellular response to arsenic-containing substance  cellular oxidant detoxification  glutathione derivative biosynthetic process  
Ontology : EGO-EBIglutathione transferase activity  protein binding  cytosol  xenobiotic metabolic process  oxidoreductase activity  L-ascorbic acid metabolic process  L-ascorbic acid metabolic process  identical protein binding  glutathione dehydrogenase (ascorbate) activity  glutathione dehydrogenase (ascorbate) activity  methylarsonate reductase activity  oxidation-reduction process  oxidation-reduction process  extracellular exosome  cellular response to arsenic-containing substance  cellular oxidant detoxification  glutathione derivative biosynthetic process  
Pathways : KEGGGlutathione metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Chemical carcinogenesis   
NDEx NetworkGSTO2
Atlas of Cancer Signalling NetworkGSTO2
Wikipedia pathwaysGSTO2
Orthology - Evolution
OrthoDB119391
GeneTree (enSembl)ENSG00000065621
Phylogenetic Trees/Animal Genes : TreeFamGSTO2
HOGENOMQ9H4Y5
Homologs : HomoloGeneGSTO2
Homology/Alignments : Family Browser (UCSC)GSTO2
Gene fusions - Rearrangements
Fusion : QuiverGSTO2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGSTO2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GSTO2
dbVarGSTO2
ClinVarGSTO2
1000_GenomesGSTO2 
Exome Variant ServerGSTO2
ExAC (Exome Aggregation Consortium)ENSG00000065621
GNOMAD BrowserENSG00000065621
Varsome BrowserGSTO2
Genetic variants : HAPMAP119391
Genomic Variants (DGV)GSTO2 [DGVbeta]
DECIPHERGSTO2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGSTO2 
Mutations
ICGC Data PortalGSTO2 
TCGA Data PortalGSTO2 
Broad Tumor PortalGSTO2
OASIS PortalGSTO2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGSTO2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGSTO2
Mutations and Diseases : HGMDGSTO2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GSTO2
DgiDB (Drug Gene Interaction Database)GSTO2
DoCM (Curated mutations)GSTO2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GSTO2 (select a term)
intoGenGSTO2
Cancer3DGSTO2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612314   
Orphanet
DisGeNETGSTO2
MedgenGSTO2
Genetic Testing Registry GSTO2
NextProtQ9H4Y5 [Medical]
TSGene119391
GENETestsGSTO2
Target ValidationGSTO2
Huge Navigator GSTO2 [HugePedia]
snp3D : Map Gene to Disease119391
BioCentury BCIQGSTO2
ClinGenGSTO2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD119391
Chemical/Pharm GKB GenePA133787053
Clinical trialGSTO2
Miscellaneous
canSAR (ICR)GSTO2 (select the gene name)
DataMed IndexGSTO2
Probes
Litterature
PubMed78 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGSTO2
EVEXGSTO2
GoPubMedGSTO2
iHOPGSTO2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:45:52 CET 2019
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