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GSTT2 (glutathione S-transferase theta 2)

Identity

Other namesGSTT2B
HGNC (Hugo) GSTT2
LocusID (NCBI) 2953
Location 22q11.23
Location_base_pair Starts at 24322314 and ends at 24326106 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GSTT2   4642
Cards
Entrez_Gene (NCBI)GSTT2  2953  glutathione S-transferase theta 2
GeneCards (Weizmann)GSTT2
Ensembl hg19 (Hinxton)ENSG00000099984 [Gene_View]  chr22:24322314-24326106 [Contig_View]  GSTT2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000099984 [Gene_View]  chr22:24322314-24326106 [Contig_View]  GSTT2 [Vega]
ICGC DataPortalENSG00000099984
cBioPortalGSTT2
AceView (NCBI)GSTT2
Genatlas (Paris)GSTT2
WikiGenes2953
SOURCE (Princeton)GSTT2
Genomic and cartography
GoldenPath hg19 (UCSC)GSTT2  -     chr22:24322314-24326106 +  22q11.23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GSTT2  -     22q11.23   [Description]    (hg38-Dec_2013)
EnsemblGSTT2 - 22q11.23 [CytoView hg19]  GSTT2 - 22q11.23 [CytoView hg38]
Mapping of homologs : NCBIGSTT2 [Mapview hg19]  GSTT2 [Mapview hg38]
OMIM600437   
Gene and transcription
Genbank (Entrez)AA682380 AK312043 BC002415 BC146929 BC146940
RefSeq transcript (Entrez)NM_000854
RefSeq genomic (Entrez)NC_000022 NC_018933 NT_011520 NT_187633 NW_004929430
Consensus coding sequences : CCDS (NCBI)GSTT2
Cluster EST : UnigeneHs.654462 [ NCBI ]
CGAP (NCI)Hs.654462
Alternative Splicing : Fast-db (Paris)GSHG0032636
Alternative Splicing GalleryENSG00000099984
Gene ExpressionGSTT2 [ NCBI-GEO ]     GSTT2 [ SEEK ]   GSTT2 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP0CG29 (Uniprot)
NextProtP0CG29  [Medical]
With graphics : InterProP0CG29
Splice isoforms : SwissVarP0CG29 (Swissvar)
Catalytic activity : Enzyme2.5.1.18 [ Enzyme-Expasy ]   2.5.1.182.5.1.18 [ IntEnz-EBI ]   2.5.1.18 [ BRENDA ]   2.5.1.18 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)GST_CTER (PS50405)    GST_NTER (PS50404)   
Domains : Interpro (EBI)Glutathione-S-Trfase_C-like    Glutathione_S-Trfase_N    GST_C    Thioredoxin-like_fold   
Related proteins : CluSTrP0CG29
Domain families : Pfam (Sanger)GST_C (PF00043)    GST_N (PF02798)   
Domain families : Pfam (NCBI)pfam00043    pfam02798   
DMDM Disease mutations2953
Blocks (Seattle)P0CG29
PDB (SRS)4MPF   
PDB (PDBSum)4MPF   
PDB (IMB)4MPF   
PDB (RSDB)4MPF   
Human Protein AtlasENSG00000099984
Peptide AtlasP0CG29
HPRD02701
IPIIPI00419250   IPI00879420   
Protein Interaction databases
DIP (DOE-UCLA)P0CG29
IntAct (EBI)P0CG29
FunCoupENSG00000099984
BioGRIDGSTT2
IntegromeDBGSTT2
STRING (EMBL)GSTT2
Ontologies - Pathways
QuickGOP0CG29
Ontology : AmiGOglutathione transferase activity  cytoplasm  metabolic process  
Ontology : EGO-EBIglutathione transferase activity  cytoplasm  metabolic process  
Pathways : KEGGGlutathione metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Chemical carcinogenesis   
Protein Interaction DatabaseGSTT2
DoCM (Curated mutations)GSTT2
Wikipedia pathwaysGSTT2
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerGSTT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GSTT2
dbVarGSTT2
ClinVarGSTT2
1000_GenomesGSTT2 
Exome Variant ServerGSTT2
SNP (GeneSNP Utah)GSTT2
SNP : HGBaseGSTT2
Genetic variants : HAPMAPGSTT2
Genomic VariantsGSTT2  GSTT2 [DGVbeta]
Mutations
ICGC Data PortalENSG00000099984 
Somatic Mutations in Cancer : COSMICGSTT2 
CONAN: Copy Number AnalysisGSTT2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)22:24322314-24326106
Mutations and Diseases : HGMDGSTT2
OMIM600437   
MedgenGSTT2
NextProtP0CG29 [Medical]
GENETestsGSTT2
Disease Genetic AssociationGSTT2
Huge Navigator GSTT2 [HugePedia]  GSTT2 [HugeCancerGEM]
snp3D : Map Gene to Disease2953
DGIdb (Drug Gene Interaction db)GSTT2
General knowledge
Homologs : HomoloGeneGSTT2
Homology/Alignments : Family Browser (UCSC)GSTT2
Phylogenetic Trees/Animal Genes : TreeFamGSTT2
Chemical/Protein Interactions : CTD2953
Chemical/Pharm GKB GenePA29030
Clinical trialGSTT2
Cancer Resource (Charite)ENSG00000099984
Other databases
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
CoreMineGSTT2
GoPubMedGSTT2
iHOPGSTT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 20 21:54:23 CET 2014

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