GSTT2B (glutathione S-transferase theta 2B)

2014-11-01  

Identity

HGNC
LOCATION
22q11.23
LOCUSID
ALIAS
GSTT2P

Other Information

Locus ID:

NCBI: 653689
HGNC: 33437
Ensembl: ENSG00000133433

Variants:

dbSNP: 653689
ClinVar: 653689
TCGA: ENSG00000133433
COSMIC: GSTT2B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000133433ENST00000290765P0CG30
ENSG00000133433ENST00000290765G9J6Q5
ENSG00000133433ENST00000404172Q6ICJ4

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Glutathione metabolismKEGGko00480
Metabolism of xenobiotics by cytochrome P450KEGGko00980
Drug metabolism - cytochrome P450KEGGko00982
Glutathione metabolismKEGGhsa00480
Metabolism of xenobiotics by cytochrome P450KEGGhsa00980
Drug metabolism - cytochrome P450KEGGhsa00982
Chemical carcinogenesisKEGGhsa05204
Chemical carcinogenesisKEGGko05204
MetabolismREACTOMER-HSA-1430728
Biological oxidationsREACTOMER-HSA-211859
Phase II conjugationREACTOMER-HSA-156580
Glutathione conjugationREACTOMER-HSA-156590
Platinum drug resistanceKEGGko01524
Platinum drug resistanceKEGGhsa01524
Fluid shear stress and atherosclerosisKEGGko05418
Fluid shear stress and atherosclerosisKEGGhsa05418

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
226767222012Influence of fetal glutathione S-transferase copy number variants on adverse reproductive outcomes.3
194244242009Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genes.0
222162612011Association of a deletion of GSTT2B with an altered risk of oesophageal squamous cell carcinoma in a South African population: a case-control study.0
262075972016Explorative genetic association study of GSTT2B copy number variant in complex disease risks.0

Citation

Dessen P

GSTT2B (glutathione S-transferase theta 2B)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64079/gstt2b