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GSTZ1 (glutathione S-transferase zeta 1)

Identity

Alias_namesglutathione transferase zeta 1
Alias_symbol (synonym)GSTZ1-1
MAAI
MAI
Other alias
HGNC (Hugo) GSTZ1
LocusID (NCBI) 2954
Atlas_Id 40776
Location 14q24.3  [Link to chromosome band 14q24]
Location_base_pair Starts at 77320887 and ends at 77331597 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ADAP2 (17q11.2) / GSTZ1 (14q24.3)PCBD2 (5q31.1) / GSTZ1 (14q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GSTZ1   4643
Cards
Entrez_Gene (NCBI)GSTZ1  2954  glutathione S-transferase zeta 1
AliasesGSTZ1-1; MAAI; MAI
GeneCards (Weizmann)GSTZ1
Ensembl hg19 (Hinxton)ENSG00000100577 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100577 [Gene_View]  chr14:77320887-77331597 [Contig_View]  GSTZ1 [Vega]
ICGC DataPortalENSG00000100577
TCGA cBioPortalGSTZ1
AceView (NCBI)GSTZ1
Genatlas (Paris)GSTZ1
WikiGenes2954
SOURCE (Princeton)GSTZ1
Genetics Home Reference (NIH)GSTZ1
Genomic and cartography
GoldenPath hg38 (UCSC)GSTZ1  -     chr14:77320887-77331597 +  14q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GSTZ1  -     14q24.3   [Description]    (hg19-Feb_2009)
EnsemblGSTZ1 - 14q24.3 [CytoView hg19]  GSTZ1 - 14q24.3 [CytoView hg38]
Mapping of homologs : NCBIGSTZ1 [Mapview hg19]  GSTZ1 [Mapview hg38]
OMIM603758   
Gene and transcription
Genbank (Entrez)AB209360 AJ001838 AK094344 AK309054 AK315154
RefSeq transcript (Entrez)NM_001312660 NM_001513 NM_145870 NM_145871
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GSTZ1
Cluster EST : UnigeneHs.655292 [ NCBI ]
CGAP (NCI)Hs.655292
Alternative Splicing GalleryENSG00000100577
Gene ExpressionGSTZ1 [ NCBI-GEO ]   GSTZ1 [ EBI - ARRAY_EXPRESS ]   GSTZ1 [ SEEK ]   GSTZ1 [ MEM ]
Gene Expression Viewer (FireBrowse)GSTZ1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2954
GTEX Portal (Tissue expression)GSTZ1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43708   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43708  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43708
Splice isoforms : SwissVarO43708
Catalytic activity : Enzyme5.2.1.2 [ Enzyme-Expasy ]   5.2.1.25.2.1.2 [ IntEnz-EBI ]   5.2.1.2 [ BRENDA ]   5.2.1.2 [ KEGG ]   
PhosPhoSitePlusO43708
Domaine pattern : Prosite (Expaxy)GST_CTER (PS50405)    GST_NTER (PS50404)   
Domains : Interpro (EBI)Glutathione-S-Trfase_C-like    Glutathione_S-Trfase_N    GST_C    GST_Zeta    GST_Zeta_C    GST_Zeta_N    Thioredoxin-like_fold   
Domain families : Pfam (Sanger)GST_C_3 (PF14497)    GST_N_3 (PF13417)   
Domain families : Pfam (NCBI)pfam14497    pfam13417   
Conserved Domain (NCBI)GSTZ1
DMDM Disease mutations2954
Blocks (Seattle)GSTZ1
PDB (SRS)1FW1   
PDB (PDBSum)1FW1   
PDB (IMB)1FW1   
PDB (RSDB)1FW1   
Structural Biology KnowledgeBase1FW1   
SCOP (Structural Classification of Proteins)1FW1   
CATH (Classification of proteins structures)1FW1   
SuperfamilyO43708
Human Protein AtlasENSG00000100577
Peptide AtlasO43708
HPRD04785
IPIIPI00013809   IPI00472241   IPI00854711   IPI01025397   IPI01025064   IPI01025181   IPI01024832   IPI01026378   IPI01026491   IPI01026517   IPI00556579   IPI00157928   
Protein Interaction databases
DIP (DOE-UCLA)O43708
IntAct (EBI)O43708
FunCoupENSG00000100577
BioGRIDGSTZ1
STRING (EMBL)GSTZ1
ZODIACGSTZ1
Ontologies - Pathways
QuickGOO43708
Ontology : AmiGOglutathione transferase activity  glutathione transferase activity  glutathione peroxidase activity  protein binding  mitochondrion  cytosol  L-phenylalanine catabolic process  L-phenylalanine catabolic process  tyrosine catabolic process  glutathione metabolic process  maleylacetoacetate isomerase activity  maleylacetoacetate isomerase activity  protein homodimerization activity  cellular oxidant detoxification  glutathione derivative biosynthetic process  
Ontology : EGO-EBIglutathione transferase activity  glutathione transferase activity  glutathione peroxidase activity  protein binding  mitochondrion  cytosol  L-phenylalanine catabolic process  L-phenylalanine catabolic process  tyrosine catabolic process  glutathione metabolic process  maleylacetoacetate isomerase activity  maleylacetoacetate isomerase activity  protein homodimerization activity  cellular oxidant detoxification  glutathione derivative biosynthetic process  
Pathways : KEGGTyrosine metabolism   
NDEx NetworkGSTZ1
Atlas of Cancer Signalling NetworkGSTZ1
Wikipedia pathwaysGSTZ1
Orthology - Evolution
OrthoDB2954
GeneTree (enSembl)ENSG00000100577
Phylogenetic Trees/Animal Genes : TreeFamGSTZ1
HOVERGENO43708
HOGENOMO43708
Homologs : HomoloGeneGSTZ1
Homology/Alignments : Family Browser (UCSC)GSTZ1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGSTZ1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GSTZ1
dbVarGSTZ1
ClinVarGSTZ1
1000_GenomesGSTZ1 
Exome Variant ServerGSTZ1
ExAC (Exome Aggregation Consortium)GSTZ1 (select the gene name)
Genetic variants : HAPMAP2954
Genomic Variants (DGV)GSTZ1 [DGVbeta]
DECIPHERGSTZ1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGSTZ1 
Mutations
ICGC Data PortalGSTZ1 
TCGA Data PortalGSTZ1 
Broad Tumor PortalGSTZ1
OASIS PortalGSTZ1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGSTZ1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGSTZ1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GSTZ1
DgiDB (Drug Gene Interaction Database)GSTZ1
DoCM (Curated mutations)GSTZ1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GSTZ1 (select a term)
intoGenGSTZ1
Cancer3DGSTZ1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603758   
Orphanet
MedgenGSTZ1
Genetic Testing Registry GSTZ1
NextProtO43708 [Medical]
TSGene2954
GENETestsGSTZ1
Target ValidationGSTZ1
Huge Navigator GSTZ1 [HugePedia]
snp3D : Map Gene to Disease2954
BioCentury BCIQGSTZ1
ClinGenGSTZ1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2954
Chemical/Pharm GKB GenePA29031
Clinical trialGSTZ1
Miscellaneous
canSAR (ICR)GSTZ1 (select the gene name)
Probes
Litterature
PubMed63 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGSTZ1
EVEXGSTZ1
GoPubMedGSTZ1
iHOPGSTZ1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:10:48 CEST 2017

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