Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GSX2 (GS homeobox 2)

Identity

Alias_symbol (synonym)Gsh2
Other aliasGSH2
HGNC (Hugo) GSX2
LocusID (NCBI) 170825
Atlas_Id 46301
Location 4q12  [Link to chromosome band 4q12]
Location_base_pair Starts at 54966248 and ends at 54968122 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
SCFD2 (4q12) / GSX2 (4q12)SCFD2 4q12 / GSX2 4q12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  del(4)(q12q12) FIP1L1/PDGFRA


External links

Nomenclature
HGNC (Hugo)GSX2   24959
Cards
Entrez_Gene (NCBI)GSX2  170825  GS homeobox 2
AliasesGSH2
GeneCards (Weizmann)GSX2
Ensembl hg19 (Hinxton)ENSG00000180613 [Gene_View]  chr4:54966248-54968122 [Contig_View]  GSX2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000180613 [Gene_View]  chr4:54966248-54968122 [Contig_View]  GSX2 [Vega]
ICGC DataPortalENSG00000180613
TCGA cBioPortalGSX2
AceView (NCBI)GSX2
Genatlas (Paris)GSX2
WikiGenes170825
SOURCE (Princeton)GSX2
Genetics Home Reference (NIH)GSX2
Genomic and cartography
GoldenPath hg19 (UCSC)GSX2  -     chr4:54966248-54968122 +  4q12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GSX2  -     4q12   [Description]    (hg38-Dec_2013)
EnsemblGSX2 - 4q12 [CytoView hg19]  GSX2 - 4q12 [CytoView hg38]
Mapping of homologs : NCBIGSX2 [Mapview hg19]  GSX2 [Mapview hg38]
OMIM616253   
Gene and transcription
Genbank (Entrez)AB028838 AI360912 BC075089 BC075090 EU446852
RefSeq transcript (Entrez)NM_133267
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_022853 NW_004929319
Consensus coding sequences : CCDS (NCBI)GSX2
Cluster EST : UnigeneHs.371899 [ NCBI ]
CGAP (NCI)Hs.371899
Alternative Splicing GalleryENSG00000180613
Gene ExpressionGSX2 [ NCBI-GEO ]   GSX2 [ EBI - ARRAY_EXPRESS ]   GSX2 [ SEEK ]   GSX2 [ MEM ]
Gene Expression Viewer (FireBrowse)GSX2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)170825
GTEX Portal (Tissue expression)GSX2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BZM3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BZM3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BZM3
Splice isoforms : SwissVarQ9BZM3
PhosPhoSitePlusQ9BZM3
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox_CS    Homeobox_dom    Homeobox_metazoa    Homeodomain-like   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)GSX2
DMDM Disease mutations170825
Blocks (Seattle)GSX2
SuperfamilyQ9BZM3
Human Protein AtlasENSG00000180613
Peptide AtlasQ9BZM3
HPRD13612
IPIIPI00001737   IPI00979845   IPI00967238   
Protein Interaction databases
DIP (DOE-UCLA)Q9BZM3
IntAct (EBI)Q9BZM3
FunCoupENSG00000180613
BioGRIDGSX2
STRING (EMBL)GSX2
ZODIACGSX2
Ontologies - Pathways
QuickGOQ9BZM3
Ontology : AmiGOregulation of respiratory gaseous exchange by neurological system process  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  spinal cord association neuron differentiation  hindbrain morphogenesis  forebrain dorsal/ventral pattern formation  olfactory bulb interneuron differentiation  telencephalon regionalization  regulation of cell migration  sequence-specific DNA binding  positive regulation of Notch signaling pathway  neuron fate specification  positive regulation of oligodendrocyte differentiation  forebrain morphogenesis  subpallium neuron fate commitment  
Ontology : EGO-EBIregulation of respiratory gaseous exchange by neurological system process  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  spinal cord association neuron differentiation  hindbrain morphogenesis  forebrain dorsal/ventral pattern formation  olfactory bulb interneuron differentiation  telencephalon regionalization  regulation of cell migration  sequence-specific DNA binding  positive regulation of Notch signaling pathway  neuron fate specification  positive regulation of oligodendrocyte differentiation  forebrain morphogenesis  subpallium neuron fate commitment  
NDEx NetworkGSX2
Atlas of Cancer Signalling NetworkGSX2
Wikipedia pathwaysGSX2
Orthology - Evolution
OrthoDB170825
GeneTree (enSembl)ENSG00000180613
Phylogenetic Trees/Animal Genes : TreeFamGSX2
HOVERGENQ9BZM3
HOGENOMQ9BZM3
Homologs : HomoloGeneGSX2
Homology/Alignments : Family Browser (UCSC)GSX2
Gene fusions - Rearrangements
Fusion: TCGASCFD2 4q12 GSX2 4q12 GBM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGSX2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GSX2
dbVarGSX2
ClinVarGSX2
1000_GenomesGSX2 
Exome Variant ServerGSX2
ExAC (Exome Aggregation Consortium)GSX2 (select the gene name)
Genetic variants : HAPMAP170825
Genomic Variants (DGV)GSX2 [DGVbeta]
DECIPHER (Syndromes)4:54966248-54968122  ENSG00000180613
CONAN: Copy Number AnalysisGSX2 
Mutations
ICGC Data PortalGSX2 
TCGA Data PortalGSX2 
Broad Tumor PortalGSX2
OASIS PortalGSX2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGSX2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGSX2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GSX2
DgiDB (Drug Gene Interaction Database)GSX2
DoCM (Curated mutations)GSX2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GSX2 (select a term)
intoGenGSX2
Cancer3DGSX2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616253   
Orphanet
MedgenGSX2
Genetic Testing Registry GSX2
NextProtQ9BZM3 [Medical]
TSGene170825
GENETestsGSX2
Huge Navigator GSX2 [HugePedia]
snp3D : Map Gene to Disease170825
BioCentury BCIQGSX2
ClinGenGSX2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD170825
Chemical/Pharm GKB GenePA162390374
Clinical trialGSX2
Miscellaneous
canSAR (ICR)GSX2 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGSX2
EVEXGSX2
GoPubMedGSX2
iHOPGSX2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:03:12 CEST 2017

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