GTF2A2 (general transcription factor IIA subunit 2)

2014-11-01  

Identity

HGNC
GTF2A2
LOCATION
15q22.2
LOCUSID
2958
ALIAS
HsT18745,T18745,TF2A2,TFIIA,TFIIA-12,TFIIA-gamma,TFIIAS
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 2958
MIM: 600519
HGNC: 4647
Ensembl: ENSG00000140307

Variants:

dbSNP: 2958
ClinVar: 2958
TCGA: ENSG00000140307
COSMIC: GTF2A2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000140307ENST00000396060P52657
ENSG00000140307ENST00000396060A0A024R5Z5
ENSG00000140307ENST00000396061P52657
ENSG00000140307ENST00000396061A0A024R5Z5
ENSG00000140307ENST00000396063P52657
ENSG00000140307ENST00000396063A0A024R5Z5
ENSG00000140307ENST00000396064A8MYR4
ENSG00000140307ENST00000484743A0A0B4J1Z5
ENSG00000140307ENST00000559706H0YK39

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Basal transcription factorsKEGGko03022
Basal transcription factorsKEGGhsa03022
Viral carcinogenesisKEGGhsa05203
Viral carcinogenesisKEGGko05203
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
HIV InfectionREACTOMER-HSA-162906
HIV Life CycleREACTOMER-HSA-162587
Late Phase of HIV Life CycleREACTOMER-HSA-162599
Transcription of the HIV genomeREACTOMER-HSA-167172
HIV Transcription InitiationREACTOMER-HSA-167161
RNA Polymerase II HIV Promoter EscapeREACTOMER-HSA-167162
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Pre-transcription EventsREACTOMER-HSA-674695
RNA Polymerase II Transcription Pre-Initiation And Promoter OpeningREACTOMER-HSA-73779
RNA Polymerase II Transcription Initiation And Promoter ClearanceREACTOMER-HSA-76042
RNA Polymerase II Transcription InitiationREACTOMER-HSA-75953
RNA Polymerase II Promoter EscapeREACTOMER-HSA-73776
RNA polymerase II transcribes snRNA genesREACTOMER-HSA-6807505

References

Pubmed IDYearTitleCitations
145709102004Specific interaction with transcription factor IIA and localization of the mammalian TATA-binding protein-like protein (TLP/TRF2/TLF).13
285393592017A transcription factor IIA-binding site differentially regulates RNA polymerase II-mediated transcription in a promoter context-dependent manner.4

Citation

Dessen P

GTF2A2 (general transcription factor IIA subunit 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64084/gtf2a2