Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GTF2E1 (general transcription factor IIE subunit 1)

Identity

Alias_namesgeneral transcription factor IIE, polypeptide 1 (alpha subunit, 56kD)
general transcription factor IIE, polypeptide 1, alpha 56kDa
Alias_symbol (synonym)TFIIE-A
FE
Other aliasTF2E1
HGNC (Hugo) GTF2E1
LocusID (NCBI) 2960
Atlas_Id 50013
Location 3q13.33  [Link to chromosome band 3q13]
Location_base_pair Starts at 120461558 and ends at 120501916 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DSG2 (18q12.1) / GTF2E1 (3q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GTF2E1   4650
Cards
Entrez_Gene (NCBI)GTF2E1  2960  general transcription factor IIE subunit 1
AliasesFE; TF2E1; TFIIE-A
GeneCards (Weizmann)GTF2E1
Ensembl hg19 (Hinxton)ENSG00000153767 [Gene_View]  chr3:120461558-120501916 [Contig_View]  GTF2E1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000153767 [Gene_View]  chr3:120461558-120501916 [Contig_View]  GTF2E1 [Vega]
ICGC DataPortalENSG00000153767
TCGA cBioPortalGTF2E1
AceView (NCBI)GTF2E1
Genatlas (Paris)GTF2E1
WikiGenes2960
SOURCE (Princeton)GTF2E1
Genetics Home Reference (NIH)GTF2E1
Genomic and cartography
GoldenPath hg19 (UCSC)GTF2E1  -     chr3:120461558-120501916 +  3q13.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GTF2E1  -     3q13.33   [Description]    (hg38-Dec_2013)
EnsemblGTF2E1 - 3q13.33 [CytoView hg19]  GTF2E1 - 3q13.33 [CytoView hg38]
Mapping of homologs : NCBIGTF2E1 [Mapview hg19]  GTF2E1 [Mapview hg38]
OMIM189962   
Gene and transcription
Genbank (Entrez)AK223401 BC005917 BC156224 BC156997 DA498425
RefSeq transcript (Entrez)NM_005513
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_005612 NW_004929311
Consensus coding sequences : CCDS (NCBI)GTF2E1
Cluster EST : UnigeneHs.445272 [ NCBI ]
CGAP (NCI)Hs.445272
Alternative Splicing GalleryENSG00000153767
Gene ExpressionGTF2E1 [ NCBI-GEO ]   GTF2E1 [ EBI - ARRAY_EXPRESS ]   GTF2E1 [ SEEK ]   GTF2E1 [ MEM ]
Gene Expression Viewer (FireBrowse)GTF2E1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2960
GTEX Portal (Tissue expression)GTF2E1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP29083   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP29083  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP29083
Splice isoforms : SwissVarP29083
PhosPhoSitePlusP29083
Domaine pattern : Prosite (Expaxy)HTH_TFE_IIE (PS51344)   
Domains : Interpro (EBI)TFIIE/TFIIEa_HTH    TFIIE_asu    TFIIE_asu_C    TFIIEa/SarR/Rpc3_HTH_dom    Znf_RING/FYVE/PHD    Znf_TFIIB   
Domain families : Pfam (Sanger)TF_Zn_Ribbon (PF08271)    TFIIE-A_C (PF11521)    TFIIE_alpha (PF02002)   
Domain families : Pfam (NCBI)pfam08271    pfam11521    pfam02002   
Domain families : Smart (EMBL)TFIIE (SM00531)  
Conserved Domain (NCBI)GTF2E1
DMDM Disease mutations2960
Blocks (Seattle)GTF2E1
PDB (SRS)1VD4    2JTX    2RNQ    2RNR   
PDB (PDBSum)1VD4    2JTX    2RNQ    2RNR   
PDB (IMB)1VD4    2JTX    2RNQ    2RNR   
PDB (RSDB)1VD4    2JTX    2RNQ    2RNR   
Structural Biology KnowledgeBase1VD4    2JTX    2RNQ    2RNR   
SCOP (Structural Classification of Proteins)1VD4    2JTX    2RNQ    2RNR   
CATH (Classification of proteins structures)1VD4    2JTX    2RNQ    2RNR   
SuperfamilyP29083
Human Protein AtlasENSG00000153767
Peptide AtlasP29083
HPRD01799
IPIIPI00019977   IPI00945436   IPI00945276   IPI00946947   
Protein Interaction databases
DIP (DOE-UCLA)P29083
IntAct (EBI)P29083
FunCoupENSG00000153767
BioGRIDGTF2E1
STRING (EMBL)GTF2E1
ZODIACGTF2E1
Ontologies - Pathways
QuickGOP29083
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  cytoplasm  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  viral process  snRNA transcription from RNA polymerase II promoter  sequence-specific DNA binding  metal ion binding  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  cytoplasm  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  viral process  snRNA transcription from RNA polymerase II promoter  sequence-specific DNA binding  metal ion binding  
Pathways : KEGGBasal transcription factors    Epstein-Barr virus infection    Viral carcinogenesis   
NDEx NetworkGTF2E1
Atlas of Cancer Signalling NetworkGTF2E1
Wikipedia pathwaysGTF2E1
Orthology - Evolution
OrthoDB2960
GeneTree (enSembl)ENSG00000153767
Phylogenetic Trees/Animal Genes : TreeFamGTF2E1
HOVERGENP29083
HOGENOMP29083
Homologs : HomoloGeneGTF2E1
Homology/Alignments : Family Browser (UCSC)GTF2E1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGTF2E1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GTF2E1
dbVarGTF2E1
ClinVarGTF2E1
1000_GenomesGTF2E1 
Exome Variant ServerGTF2E1
ExAC (Exome Aggregation Consortium)GTF2E1 (select the gene name)
Genetic variants : HAPMAP2960
Genomic Variants (DGV)GTF2E1 [DGVbeta]
DECIPHER (Syndromes)3:120461558-120501916  ENSG00000153767
CONAN: Copy Number AnalysisGTF2E1 
Mutations
ICGC Data PortalGTF2E1 
TCGA Data PortalGTF2E1 
Broad Tumor PortalGTF2E1
OASIS PortalGTF2E1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGTF2E1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGTF2E1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GTF2E1
DgiDB (Drug Gene Interaction Database)GTF2E1
DoCM (Curated mutations)GTF2E1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GTF2E1 (select a term)
intoGenGTF2E1
Cancer3DGTF2E1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM189962   
Orphanet
MedgenGTF2E1
Genetic Testing Registry GTF2E1
NextProtP29083 [Medical]
TSGene2960
GENETestsGTF2E1
Huge Navigator GTF2E1 [HugePedia]
snp3D : Map Gene to Disease2960
BioCentury BCIQGTF2E1
ClinGenGTF2E1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2960
Chemical/Pharm GKB GenePA29036
Clinical trialGTF2E1
Miscellaneous
canSAR (ICR)GTF2E1 (select the gene name)
Probes
Litterature
PubMed57 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGTF2E1
EVEXGTF2E1
GoPubMedGTF2E1
iHOPGTF2E1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:03:13 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.