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GTF2E2 (general transcription factor IIE subunit 2)

Identity

Alias_namesgeneral transcription factor IIE, polypeptide 2 (beta subunit, 34kD)
general transcription factor IIE, polypeptide 2, beta 34kDa
Alias_symbol (synonym)TFIIE-B
FE
TF2E2
Other aliasTTD6
HGNC (Hugo) GTF2E2
LocusID (NCBI) 2961
Atlas_Id 55936
Location 8p12  [Link to chromosome band 8p12]
Location_base_pair Starts at 30584426 and ends at 30657618 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GTF2E2 (8p12) / ACE (17q23.3)GTF2E2 (8p12) / FBXO16 (8p21.1)GTF2E2 (8p12) / GSR (8p12)
GTF2E2 (8p12) / GTF2E2 (8p12)GTF2E2 (8p12) / NARS2 (11q14.1)GTF2E2 (8p12) / RBPMS (8p12)
RNASEK-C17orf49 (17p13.1) / GTF2E2 (8p12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GTF2E2   4651
Cards
Entrez_Gene (NCBI)GTF2E2  2961  general transcription factor IIE subunit 2
AliasesFE; TF2E2; TFIIE-B; TTD6
GeneCards (Weizmann)GTF2E2
Ensembl hg19 (Hinxton)ENSG00000197265 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197265 [Gene_View]  chr8:30584426-30657618 [Contig_View]  GTF2E2 [Vega]
ICGC DataPortalENSG00000197265
TCGA cBioPortalGTF2E2
AceView (NCBI)GTF2E2
Genatlas (Paris)GTF2E2
WikiGenes2961
SOURCE (Princeton)GTF2E2
Genetics Home Reference (NIH)GTF2E2
Genomic and cartography
GoldenPath hg38 (UCSC)GTF2E2  -     chr8:30584426-30657618 -  8p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GTF2E2  -     8p12   [Description]    (hg19-Feb_2009)
EnsemblGTF2E2 - 8p12 [CytoView hg19]  GTF2E2 - 8p12 [CytoView hg38]
Mapping of homologs : NCBIGTF2E2 [Mapview hg19]  GTF2E2 [Mapview hg38]
OMIM189964   616943   
Gene and transcription
Genbank (Entrez)AA483281 BC001775 BC030572 BX421791 S67861
RefSeq transcript (Entrez)NM_001348353 NM_002095
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GTF2E2
Cluster EST : UnigeneHs.77100 [ NCBI ]
CGAP (NCI)Hs.77100
Alternative Splicing GalleryENSG00000197265
Gene ExpressionGTF2E2 [ NCBI-GEO ]   GTF2E2 [ EBI - ARRAY_EXPRESS ]   GTF2E2 [ SEEK ]   GTF2E2 [ MEM ]
Gene Expression Viewer (FireBrowse)GTF2E2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2961
GTEX Portal (Tissue expression)GTF2E2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP29084   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP29084  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP29084
Splice isoforms : SwissVarP29084
PhosPhoSitePlusP29084
Domaine pattern : Prosite (Expaxy)TFIIE_BETA_C (PS51351)   
Domains : Interpro (EBI)TFIIE-bsu    TFIIE_bsu_DNA-bd    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)TFIIE_beta (PF02186)   
Domain families : Pfam (NCBI)pfam02186   
Conserved Domain (NCBI)GTF2E2
DMDM Disease mutations2961
Blocks (Seattle)GTF2E2
PDB (SRS)1D8J    1D8K    5GPY    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD   
PDB (PDBSum)1D8J    1D8K    5GPY    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD   
PDB (IMB)1D8J    1D8K    5GPY    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD   
PDB (RSDB)1D8J    1D8K    5GPY    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD   
Structural Biology KnowledgeBase1D8J    1D8K    5GPY    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD   
SCOP (Structural Classification of Proteins)1D8J    1D8K    5GPY    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD   
CATH (Classification of proteins structures)1D8J    1D8K    5GPY    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD   
SuperfamilyP29084
Human Protein AtlasENSG00000197265
Peptide AtlasP29084
HPRD01800
IPIIPI00019981   IPI00974324   IPI01016053   IPI00984666   
Protein Interaction databases
DIP (DOE-UCLA)P29084
IntAct (EBI)P29084
FunCoupENSG00000197265
BioGRIDGTF2E2
STRING (EMBL)GTF2E2
ZODIACGTF2E2
Ontologies - Pathways
QuickGOP29084
Ontology : AmiGODNA binding  RNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  transcription factor TFIID complex  transcription factor TFIIE complex  cytosol  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  nuclear speck  snRNA transcription from RNA polymerase II promoter  
Ontology : EGO-EBIDNA binding  RNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  transcription factor TFIID complex  transcription factor TFIIE complex  cytosol  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  nuclear speck  snRNA transcription from RNA polymerase II promoter  
Pathways : KEGGBasal transcription factors    Epstein-Barr virus infection    Viral carcinogenesis   
NDEx NetworkGTF2E2
Atlas of Cancer Signalling NetworkGTF2E2
Wikipedia pathwaysGTF2E2
Orthology - Evolution
OrthoDB2961
GeneTree (enSembl)ENSG00000197265
Phylogenetic Trees/Animal Genes : TreeFamGTF2E2
HOVERGENP29084
HOGENOMP29084
Homologs : HomoloGeneGTF2E2
Homology/Alignments : Family Browser (UCSC)GTF2E2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGTF2E2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GTF2E2
dbVarGTF2E2
ClinVarGTF2E2
1000_GenomesGTF2E2 
Exome Variant ServerGTF2E2
ExAC (Exome Aggregation Consortium)GTF2E2 (select the gene name)
Genetic variants : HAPMAP2961
Genomic Variants (DGV)GTF2E2 [DGVbeta]
DECIPHERGTF2E2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGTF2E2 
Mutations
ICGC Data PortalGTF2E2 
TCGA Data PortalGTF2E2 
Broad Tumor PortalGTF2E2
OASIS PortalGTF2E2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGTF2E2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGTF2E2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GTF2E2
DgiDB (Drug Gene Interaction Database)GTF2E2
DoCM (Curated mutations)GTF2E2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GTF2E2 (select a term)
intoGenGTF2E2
Cancer3DGTF2E2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM189964    616943   
Orphanet10319   
MedgenGTF2E2
Genetic Testing Registry GTF2E2
NextProtP29084 [Medical]
TSGene2961
GENETestsGTF2E2
Target ValidationGTF2E2
Huge Navigator GTF2E2 [HugePedia]
snp3D : Map Gene to Disease2961
BioCentury BCIQGTF2E2
ClinGenGTF2E2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2961
Chemical/Pharm GKB GenePA29037
Clinical trialGTF2E2
Miscellaneous
canSAR (ICR)GTF2E2 (select the gene name)
Probes
Litterature
PubMed57 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGTF2E2
EVEXGTF2E2
GoPubMedGTF2E2
iHOPGTF2E2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:10:49 CEST 2017

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