Identity
HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
BTF4,RAP74,TF2F1,TFIIF
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2962
MIM: 189968
HGNC: 4652
Ensembl: ENSG00000125651
Variants:
dbSNP: 2962
ClinVar: 2962
TCGA: ENSG00000125651
COSMIC: GTF2F1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000125651 | ENST00000394456 | P35269 |
| ENSG00000125651 | ENST00000593678 | M0QXD6 |
| ENSG00000125651 | ENST00000595047 | M0R0R9 |
| ENSG00000125651 | ENST00000598607 | M0R0Z3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37822142 | 2023 | Leptin prevents aberrant targeting of tau to hippocampal synapses via PI 3 kinase driven inhibition of GSK3β. | 3 |
| 37822142 | 2023 | Leptin prevents aberrant targeting of tau to hippocampal synapses via PI 3 kinase driven inhibition of GSK3β. | 3 |
| 29225078 | 2018 | Regulation of Androgen Receptor Activity by Transient Interactions of Its Transactivation Domain with General Transcription Regulators. | 23 |
| 29225078 | 2018 | Regulation of Androgen Receptor Activity by Transient Interactions of Its Transactivation Domain with General Transcription Regulators. | 23 |
| 22244332 | 2012 | Transcriptional regulation by Pol II(G) involving mediator and competitive interactions of Gdown1 and TFIIF with Pol II. | 44 |
| 22343046 | 2012 | Activator-mediator binding stabilizes RNA polymerase II orientation within the human mediator-RNA polymerase II-TFIIF assembly. | 13 |
| 22244332 | 2012 | Transcriptional regulation by Pol II(G) involving mediator and competitive interactions of Gdown1 and TFIIF with Pol II. | 44 |
| 22343046 | 2012 | Activator-mediator binding stabilizes RNA polymerase II orientation within the human mediator-RNA polymerase II-TFIIF assembly. | 13 |
| 21896726 | 2011 | Transcription factor TFIIF is not required for initiation by RNA polymerase II, but it is essential to stabilize transcription factor TFIIB in early elongation complexes. | 29 |
| 21896726 | 2011 | Transcription factor TFIIF is not required for initiation by RNA polymerase II, but it is essential to stabilize transcription factor TFIIB in early elongation complexes. | 29 |
| 18950845 | 2009 | Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study. | 5 |
| 19215094 | 2009 | NMR structure of a complex formed by the carboxyl-terminal domain of human RAP74 and a phosphorylated peptide from the central domain of the FCP1 phosphatase. | 6 |
| 18950845 | 2009 | Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study. | 5 |
| 19215094 | 2009 | NMR structure of a complex formed by the carboxyl-terminal domain of human RAP74 and a phosphorylated peptide from the central domain of the FCP1 phosphatase. | 6 |
| 17848138 | 2008 | Genomic location of the human RNA polymerase II general machinery: evidence for a role of TFIIF and Rpb7 at both early and late stages of transcription. | 19 |
Citation
Dessen P
GTF2F1 (general transcription factor IIF subunit 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/40777/gtf2f1
